African Journal of
Biotechnology

  • Abbreviation: Afr. J. Biotechnol.
  • Language: English
  • ISSN: 1684-5315
  • DOI: 10.5897/AJB
  • Start Year: 2002
  • Published Articles: 12480

Full Length Research Paper

The anti-tick properties of the root extracts of Senna italica subsp. arachoides

  Magano S. R.1*, Thembo K. M.2, Ndlovu S. M.3 and Makhubela N. F. H.3      
  1Department of Biology, University of Limpopo, South Africa. 2Medical Research Council, Cape Town, South Africa. 3Department of Chemistry, University of Limpopo, South Africa.  
Email: [email protected]

  •  Accepted: 15 November 2007
  •  Published: 19 February 2008

Abstract

 

This study examined the anti-tick properties of the root extracts of Senna italicasubsp. arachoides against adults of Hyalomma marginatum rufipes. Of the hexane, chloroform, dichloromethane, ethyl acetate and methanol extracts tested, only ethyl acetate extracts proved to be potent against adults of H. marginatumrufipes. The acaricidal activity of the ethyl acetate root extract of S. italica subsp.arachoides increased significantly (P < 0.05) with concentration when tested against H. marginatum rufipes. The potency of the extract persisted to the second day. The LC50 of the ethyl acetate root extract of S. italica subsp. arachoides in 24 h was 8.66% (w/v) while in 48 h was 3.59% (w/v). Chemical characterization of the extracts revealed 1,2-benzenedicarboxylic acid, dibutyl ester, 1,8-dihydroxy-3-methylanthraquinone, 1,2-benzenedicarboxylic acid, bis(2-ethylhexyl) ester, hexadecanoic acid, 9-hexadecanoic acid as components.

 

Key words: Senna italica subsp. arachoides, Hyalomma marginatum rufipes, contact toxicity, root extract.

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This article is published under the terms of the Creative Commons Attribution License 4.0

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