Journal of
Medicinal Plants Research

  • Abbreviation: J. Med. Plants Res.
  • Language: English
  • ISSN: 1996-0875
  • DOI: 10.5897/JMPR
  • Start Year: 2007
  • Published Articles: 3831

Full Length Research Paper

A double blind, placebo-controlled, crossover study on the effect of MS14, an herbal-marine drug, on quality of life in patients with multiple sclerosis

Mohsen Naseri1*, Amrollah Ahmadi2, Kourosh Gharegozli3, Masoud Nabavi4, Soghrat Faghihzadeh5, Nevoid Ashtarian6, Fariba Montazami6, Hossein Rezaeizadeh7
1Shahed Medicinal Plants Research Center, Head of Department of Traditional Iranian Medicine, Shahed University, P. O. Box: 13185-1678, Tehran, Iran. 2Traditional Iranian Medicine Research Center, Shahed University, P. O. Box: 13185-1678, Tehran, Iran. 3Department of Neurology, Shahid Beheshti University of Medical Science, P. O. Box 13185 - 1678, Tehran, Iran. 4Deparment of Neurology, Faculty of Medicine, Shahed University, P. O. Box: 13185-1678, Tehran, Iran. 5Deparment of Biostatistics, Faculty of Medicine, Tarbiat Modarres University, P. O. Box: 13185-1678, Tehran, Iran. 6Loghman Hospital, Shahid Beheshti University of Medical Science, P. O. Box 13185 -1678, Tehran, Iran. 7Student's Scientific Research Center, Medical Sciences/University of Tehran, P. O. Box: 13185-1678, Tehran, Iran.
Email: [email protected]

  •  Accepted: 31 March 2009
  •  Published: 30 April 2009

Abstract

Current research into new drugs is focused on agents that will change multiple sclerosis process. MS14 is an herbal-marine product, based on anecdotal evidences in traditional Iranian medicine (TIM). The objective of this study was to assess the safety and efficacy of MS14 in volunteer patients. This study was a randomized placebo-controlled, double blind, crossover clinical trial in patients who had not responded to common MS drug regimens. Common toxicity criteria and quality of life (QOL) questionnaire were assessed. No significant changes were observed in vital signs, biochemical, hematological, liver and kidney function tests. Moreover, the improvement of patients' mobility (lower limb) was significant, comparison before treatment and placebo group (p-value: 0.048). These results suggest the potential benefits of MS14 on QOL in patients and attenuating and remodeling of multiple sclerosis disease and although the results confirm the safety and relative efficacy of MS14.

 

Key words: Multiple sclerosis, MS14, Iranian traditional medicine.

Copyright © 2024 Author(s) retain the copyright of this article.

This article is published under the terms of the Creative Commons Attribution License 4.0

Back to Vol. 3 No. 4
Back to articles
  • Articles on Google by:
SUBSCRIBE TO RSS
SUBMIT MANUSCRIPT
CONFERENCES