Journal of
Medicinal Plants Research

  • Abbreviation: J. Med. Plants Res.
  • Language: English
  • ISSN: 1996-0875
  • DOI: 10.5897/JMPR
  • Start Year: 2007
  • Published Articles: 3831

Full Length Research Paper

Antibacterial and antioxidant activity of the extracts of Waltheria indica Linn. collected from Capricorn District, Limpopo Province, South Africa

Mongalo N. I.1*, Opoku A. R.2 and Zobolo A. M.1
1Department of Botany, University of Zululand, Private Bag X 1001, Kwadlangezwa 3886.South Africa. 2Department of Biochemistry and Microbiology, University of Zululand, Private Bag X 1001, Kwadlangezwa 3886, Republic of South Africa.
Email: [email protected]

  •  Accepted: 20 April 2012
  •  Published: 10 November 2012

Abstract

Waltheria indica L., a member of Sterculiaceae family, is widely used traditionally to treat a variety of infections in humans. Roots of W. indica were collected from William Show farm, Blouberg Area-Limpopo Province, South Africa. Water, ethanol, methanol and acetone extracts were tested for antibacterial activity. Zones of inhibition ranged from 8.9 ± 0.79 to 20.2 ± 0.57 and were dose dependent. Methanol extract exhibited lowest of 0.52 mg/ml against Bacillus cereus. Ethanol extract exhibited lowest minimum bactericidal concentrations against B. cereus at 0.65 mg/ml. Methanol extract was also tested for antioxidant activity using 2, 2-diphenyl-1-picryhydrazyl (DPPH) radical scavenging assay and exhibited 75.45 ± 2.76 at a concentration of 0.75 mg/100 ml. DPPH inhibition was also found to be dose dependent. These biological activities observed in the selected extracts validate ethnomedicinal use of W. indica.

 

Key words: Waltheria indica L, antibacterial, antioxidant, ethnomedicine

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This article is published under the terms of the Creative Commons Attribution License 4.0

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