Journal of
Medicinal Plants Research

  • Abbreviation: J. Med. Plants Res.
  • Language: English
  • ISSN: 1996-0875
  • DOI: 10.5897/JMPR
  • Start Year: 2007
  • Published Articles: 3833

Full Length Research Paper

In vitro biological screening and evaluation of free radical scavenging activities of medicinal plants from the Brazilian Cerrado

Maria Carolina S. Marques1, Lidilhone Hamerski1, Fernanda R. Garcez1, Caroline Tieppo1, Mariela Vasconcelos2, Eduardo Caio Torres-Santos2, Marilene Chang3 and Walmir Silva Garcez1*    
1Centro de Ciências Exatas e Tecnologia, Universidade Federal de Mato Grosso do Sul, Av. Senador Filinto Muller 1555, Campo Grande, MS, 79074-460, Brazil. 2Laboratório de Bioquímica de Tripanossomatídeos, Instituto Oswaldo Cruz, Rio de Janeiro, RJ, Brazil. 3Centro de Ciências Biológicas e da Saúde, Universidade Federal de Mato Grosso do Sul, Campo Grande, MS, Brazil.      
Email: [email protected]

  •  Accepted: 26 March 2013
  •  Published: 17 April 2013

Abstract

A total of 23 extracts derived from 14 medicinal plant species from Brazilian savanna (“Cerrado”), selected by ethnopharmacological information, was screened for leishmanicidal, antibacterial, antifungal and radical scavenging activities and toxicity to brine shrimp (Artemia salina) larvae. Crude extracts from 9 of these species showed potent activity in one or more of these assays.

 

Key words: Antileishmanial, antibacterial activity, antifungal activity, Artemia salina, diphenylpicrylhydrazyl (DPPH), Cerrado.

 

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This article is published under the terms of the Creative Commons Attribution License 4.0

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