Journal of
General and Molecular Virology

  • Abbreviation: J. Gen. Mol. Virol.
  • Language: English
  • ISSN: 2141-6648
  • DOI: 10.5897/JGMV
  • Start Year: 2009
  • Published Articles: 37

Full Length Research Paper

The first isolation of chikungunya virus from non-human primates in Malaysia

Y. Apandi1*, W. A. Nazni2, Z. A. Noor Azleen2, I. Vythilingam3, M. Y. Noorazian3, A. H. Azahari2, S. Zainah1 and H. L. Lee2
  1Virology Unit, Institute for Medical Research, Kuala Lumpur, Malaysia. 2Medical Entomology Unit, Institute for Medical Research, Kuala Lumpur, Malaysia. 3Parasitology Unit, Institute for Medical Research, Kuala Lumpur, Malaysia.
Email: [email protected]

  •  Accepted: 17 September 2009
  •  Published: 30 October 2009

Abstract

 

Chikungunya is a mosquito borne disease caused by chikungunya virus (CHIKV). The virus is transmitted to human by Aedes genus mosquitoes. Transmission cycles of CHIKV can be man - mosquito - man (urban cycle) or animal - mosquito - man (sylvatic cycle). Sylvatic transmission cycle of CHIKV has been described in Africa and may play a role in re-emergence of CHIKV infection. In Malaysia, CHIKV- neutralizing antibodies have been detected among wild monkeys in mid 1960s but so far CHIKV has never been isolated in monkeys.

 

Key words: Chikungunya virus, sylvatic cycle, non human primates, CHIKV genotypes.