International Journal of
Medicine and Medical Sciences

  • Abbreviation: Int. J. Med. Med. Sci.
  • Language: English
  • ISSN: 2006-9723
  • DOI: 10.5897/IJMMS
  • Start Year: 2009
  • Published Articles: 535

Full Length Research Paper

Isolation and characterization of a new chalcone from the leaves of Heteropyxis natalensis

Adesanwo, J. K.
  • Adesanwo, J. K.
  • Chemistry Department, Obafemi Awolowo University, Ile-Ife Osun State, Nigeria
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Shode, F. O.
  • Shode, F. O.
  • School of Chemistry, Westville Campus, University of KwaZulu-Natal, P/Bag X54001, Durban, South Africa.
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Aiyelaagbe, O.
  • Aiyelaagbe, O.
  • Chemistry Department University of Ibadan, Nigeria.
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Oyede, R. T.
  • Oyede, R. T.
  • School of Chemistry, Westville Campus, University of KwaZulu-Natal, P/Bag X54001, Durban, South Africa.
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Baijnath, H.
  • Baijnath, H.
  • School of Conservation and Biological Sciences, Westville Campus, University of KwaZulu-Natal, P/Bag X54001, Durban, South Africa.
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  •  Accepted: 16 January 2009
  •  Published: 28 February 2009

Abstract

Chromatographic analysis of the defatted dichloromethane extract of the leaves ofHeteropyxis natalensis afforded the isolation of (E)-1-(2’,4’-dihydroxy, 5’-methoxy, 3’-methylphenyl)-3-phenylprop-2-en-1-one (R1 = Me; R2 = OH; R3 = OMe; R4 = H) a  chalcone. The structure of this compound was established by its spectroscopic data-1D, 2D-NMR, EIMS and HR-EIMS.

Key words: Chalcones, Heteropyxis natalensis, heteropyxidaceae, flavone

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