Abstract

An attempt had been made to investigate the seroepidemiology of Helicobacter pylori infection with influencing factors affecting the new entrants and final year medical students. The study was based on the analysis of primary data taken from new entrants and final year MBBS students of Sylhet MAG Osmani Medical College, Bangladesh. To detect H. pylori IgG among first year and final year medical students, we compared the seroprevalence of H. pylori lgG between two groups and found influencing factors affecting the seroprevalence and any association between them. In this study, 80 students from each group were studied. Relevant variables were taken in a pre-designed questionnaire. H. pylori lgG was detected by using ELISA method. The study showed that in first year 41 (50%) and in final year 47 (about 59%) students were H. pylori lgG positive respectively. Numerically final year students were more affected by H. pylori than new entrants. The study revealed that in first year, positive seroprevalence of H. pylori significantly differed with only travel history of students. On the other hand, in final year, positive seroprevalence of H. pylori significantly differ with gender of students. Further study needed to be carried out for large scale population to make general inference about seroepidemiology of H. pylori.

Key words: Helicobacter pylori, seroprevalence, seroepidemiology.