In vitro techniques are a method for in vitro propagation and possible conservation of plants. It is the only way of propagating new varieties generated via genetic engineering and gene editing. But the problem of phenolic exudates is one of the factors that limited the easy way of generating plantlets from the mother plants. This paper reviews the different factors that limit in vitro propagation, and pointed out how phenols are produced and their added value from different literature. It also discussed the factors that trigger the production and oxidation of phenolics and their effect on somatic regeneration and in vitro conservation. Finally, our review article shows some strategies reported for reducing phenolic oxidation and wishing enhanced in vitro regeneration and conservation of plants. Different pieces of literature have been assessed and the data on different crops outlined. The overall thoughts and strategies for reducing the problem of phenol oxidation are discussed and presented as the way forward.

Keywords: Phenol, phenolic oxidation, Somatic embryogenesis, tissue culture,