September 2010

Lead toxicity and some subsets of motor skill: Comparative evaluation of adult and prenatally exposed rats

Research has shown that even low levels of lead (Pb) exposure are dangerous. Thus, Pb exposure/toxicity continues to be a leading environmental health issue for children and women of childbearing age. A variety of toxic effects caused by Pb exposure during gestation and early childhood have been reported in both human and animal studies.  Adult Wistar rats of both sexes were used for this study. They were housed in...

Author(s): P. D. Shallie, A. K. Adefule, H. B. Akpan, O. O. Olubiyi, P. B. Fakunle and E. N. Adejumo

September 2010

Efficacy of oxcarbazepine add-on therapy on intractable seizures in Children

Almost 50 million people in the world, a third of whom children, suffer from epilepsy. Up to 30% of them develop refractory epilepsy. In this group, there is a need for more efficacious antiepileptic drugs. This study was undertaken to evaluate the efficacy and safety of oxcarbazepine a new antiepileptic drug, as an adjunction therapy in children with refractory epilepsy. From February, 2004 until September 2006, 30...

Author(s): Azita Tavassoli, Mohamad Ghofrani, Mohsen Rouzrokh and Eznollah Azargashb