October 2020
Anticonvulsant activities of friedelan-3-one and n-dotriacontane both isolated from Harungana madagascariensis Lam (Hypericaceae) seeds extracts
Chemical investigation of the crude methanol/methylene chloride (1:1) extract of the seeds of Harungana madagascariensis resulted in the isolation of two known compounds namely n-dotriacontane and friedelan-3-one. The structures of the isolated compounds were determined on the basis of 1D NMR spectroscopy and comparison with literature data. The crude extract and the two compounds were evaluated for their anticonvulsant...
October 2020
Hypoglycaemic effects of Salvia officinalis extracts on alloxan-induced diabetic Swiss albino mice
Diabetes mellitus is the fourth killer disease globally. The available management strategies are quite expensive and sometimes unsafe. This necessitates the need for bio-active drugs from medicinal plants. Although Salvia officinalis (sage) is used in herbal medicine, the scientific validation for anti-diabetic effects of various extracts has been elusive. The present study aimed to determine and compare the...
October 2020
Eerdun Wurile protects neuron and promotes neurite outgrowth through regulation of apoptotic gene expression in PC-12 cells
Eerdun Wurile (EW) is one of the most widely used traditional Mongolian medicines for stroke recovery. Previous studies revealed that EW regulates brain gene expression in a rat model of middle cerebral artery occlusion (MCAO). However, the fraction of active components and the specific genes regulated by such fractions have not been elucidated clearly. The study shows that the extracts of EW regulate the expression of...
October 2020
Larvicide and repellent activity of Hypenia irregularis (Benth.) Harley in the alternative control of mosquito Aedes aegypti
Dengue is an emerging epidemic disease and among those transmitted by the Aedes aegypti mosquito, it is the one with the highest number of cases and cases with death. With the wide dissemination of the beneficial effects of medicinal plants and the use in agriculture as a pesticide, studies on the prospection of plants with toxic activity have been increasing, highlighting extracts and essential oils. The objective of...
October 2020
Future molecular medicine from white frangipani (Plumeria alba L.): A review
White frangipani (Plumeria alba L.) is tropical and subtropical plants, have been familiar used in many traditional medication as well as aromatherapy, especially for the flower part. Scientific study, but was not so many, reporting some pharmacological and toxicological effects of this plant which lead to more depth study at molecular level. This review describes the pharmacological and toxicological effect of the...
October 2020
Evaluation of antioxidant and protective effect against genotoxic damage of two extracts of chaya leaves (Cnidoscolus aconitifolius)
Stress, excessive consumption of processed foods, pollutants and many other factors of today's life have caused oxidative stress in our body and damage to genetic material in our cells, leading to diseases such as diabetes, hypertension, cancer, metabolic syndrome, among others. Medicine has returned to take up traditional remedies mainly in plants. Chaya (Cnidoscolus aconitifolius) has been studied in this regard,...
October 2020
Antibacterial activities of ethyl acetate and methanol leaf extracts of Psidium guajava and Carica papaya on bacterial pathogens isolated from manual toothbrushes
Toothbrush has become a potential source of infection, owing to contamination by various pathogens as a result of poor oral hygiene awareness and practices. This study investigated the antibacterial activities of ethyl acetate and methanol leaf-extracts of Psidium guajava (guava) and Carica papaya (paw-paw) on bacteria pathogens isolated from toothbrushes. A total of 100 manual used toothbrushes of different brands were...
October 2020
Optimization by mixture design of the antimicrobial activities of five selected essential oils
The individual antimicrobial activities of essential oils have been reported by many authors. However, there is little information about the effects of their mixtures in order to maximize their effect and reduce the growing resistance of pathogens to existing medicines. So, the aim of this work is to optimize the antibacterial and antifungal activities of essential oils from Plectranthus glandulosus, Ocimum gratissimum,...
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