March 2015

Karyotype analysis of obtained tetraploid in medicinal plant (Platycodon grandiflorus)

Platycodon grandiflorus is an important medicinal plant in China. Induction of polyploidy was successfully attempted in this medicinal plant using 0.05% colchicine semi-solid under 72 h by apical shoot tip treatment of young seedlings, and then 50% mutant plants were obtained. It was testified by the chromosome number in mitosis and its karyotype analysis for diploid control and obtained mutants. The results showed that...

Author(s): Fuhong Yang, Lingjiao Li, Erhua Rong, Yongbo He, Xiaoming Zhao and Yuxiang Wu  

March 2015

Comparison of allopathic and herbal medicine for the treatment of Entamoeba histolytica: A double blind clinical trial

This parallel, randomized, double blind clinical trial was designed to compare allopathic drugs [a combination of metronidazole + diloxanide furoate (MDF)] with Endemali (herbal product) for therapeutic cure rate and side effects in order to find out the most suitable drug for this killer disease. This double blind randomized clinical trial was conducted in two areas of Karachi, Pakistan after approval from ethical...

Author(s): Muhammad Irfanullah Siddiqui, and Khan Usmanghani  

March 2015

Phytochemical, antioxidant and cytotoxic analysis of Brazilian cerrado plants: Preliminary evidence of their antitumor activity

The aim of this study was to analyze the antitumor activity of Anacardium humile A. St.-Hil., Brosimum gaudichaudii Trécul and Tabebuia avellanedae Lorentz ex Griseb species, which are distributed in the Cerrado region of Brazil. Qualitative and quantitative analyses were also conducted on the bark and leaf extracts and antioxidant and cytotoxic activities were studied. The results showed that the bark and leaf...

Author(s): Thiago Antônio de Sousa Araújo⊃,⊃, Tadeu José da Silva Peixoto Sobrinho⊃, Jaciana dos Santos Aguiar⊃, Ana Carolina Oliveira da Silva⊃, Felipe Uchôa Brito⊃, Teresinha Gonçalves da Silva⊃, Elba Lucia Cavalcanti de Amorim⊃ and Maria Cristina da Silva Pranchevicius,  

March 2015

Podophyllotoxin content in rhizome and root samples of Podophyllum hexandrum Royle populations from Indian Himalayan region

The podophyllotoxin content in rhizome and root samples of Podophyllum hexandrum Royle (with leaf morphological variants, that is, 1, 2 and 3L), an endangered perennial herb and a source of highly valued aryltetralin lignan, collected from 17 different populations (2800 to 3600 m asl) spread across Uttarakhand State of Indian Central Himalaya were analyzed by high performance liquid chromatography (HPLC).  In...

Author(s): Hemant Pandey, Anil Kumar, Lok Man S. Palni, and Shyamal K. Nandi  

March 2015

Alkaloid constitution of Nerium oleander using gas chromatography-mass spectroscopy (GC-MS)

Oleander is an evergreen shrub or small tree from 5 to 25-ft tall containing gummy sticky sap in the dogbane family Apocynaceae. In this study, the alkaloid compounds of Nerium oleander (NO) have been evaluated. The chemical compositions of the leaf ethanol extract of N. oleander were investigated using gas chromatography-mass specroscopy (GC-MS). GC-MS analysis of N. oleander alkaloid leaf ethanol extract revealed the...

Author(s): Imad Hadi Hameed, Huda Jasim, Muhanned Abdulhasan Kareem and Ameera Omran Hussein