October 2018

In vivo antitumor effect of the aqueous extract of Punica granatum in the sarcoma 180 murine model

Punica granatum, specifically the fruit, has a long ethno medical history and is a phytochemical reservoir of great medicinal value. The phytochemistry and pharmacological actions of all P. granatum components suggest a wide range of clinical applications. The aim of the present study is to investigate the anticancer potential of aqueous extract of P. granatum (AEPG) in experimental models. The chemical composition of...

Author(s): Talita Santos Bastos, Danilo Barauna Nascimento da Costa, Rafael Barreto Vieira Valois, Sara Maria Thomazzi, Marismar Fernandes do Nascimento, Grace Anne Azevedo Dória, Ricardo Guimarães Amaral, Silvana Vieira Floresta Gomes, Isabel Bezerra Lima-Verde, Cláudia Andréa Lima Cardoso, Francine Ferreira Padilha, Margarete Zanardo Gomes, Juliana Cordeiro Cardoso, Adriana Andrade Carvalho andRicardo Luiz Cavalcanti de Albuquerque-Júnior,   

October 2018

Effects of methanolic calyx extract of Hibiscus sabdariffa on body weight, blood cholesterol and liver marker enzymes in Wistar rats

Eighty male albino rats were used to investigate the effects of methanolic calyx extract of Hibiscus sabdariffa on body weight, blood cholesterol and liver enzymes markers. Twenty-eight days oral administration of 100, 200, 400 and 800 mg/kg body weight of the extract showed a significant (p<0.05) time-dependent decrease in the body weights of all the treated groups when compared with the control, with 100 mg/kg...

Author(s): Emmanuel I. Nnamonu, Vincent C. Ejere, Edmund C. Mbegbu, Chiemekam S. Ezechukwu and Anthony O. Ejim  

October 2018

Knowledge of medicinal plants used by residents in two peripheral districts of Boa Vista, Roraima, Northern Brazilian Amazon: Phytotherapy as a new strategy in collective health

The aim of the study was to describe local knowledge about the use of medicinal plants cited by study participants, as well as to examine how phytotherapy serves as an important strategy of integrative and complementary practice in coping with health problems. The research is characterized as an exploratory study of the descriptive type. Non-probabilistic snowball sampling generated a sample of one hundred and ten...

Author(s): Kristiane Alves Araújo, Ires Paula de Andrade Miranda, Calvino Camargo and Maxim Repetto