June 2011
Landmarks in the field of diabetes
Many advances have occurred in field of diabetes in the past 25 years which have changed our practice of diabetes management. Changes like human insulin, insulin delivering devices, insulin pumps and glucometer along with DPP-IVinhibitors that have placebo like tolerability have revolutionized the treatment of diabetes. Studies like DCCT (Diabetes Control and Complications Trial), UKPDS (United Kingdom Prospective...
May 2011
Oxidative stress and not endothelial nitric oxide synthase gene polymorphism involved in diabetic nephropathy
Diabetic Nephropathy (DN) poses a major health problem. There is strong evidence for a potential role of the eNOS gene. The aim of this case control study was to investigate the possible role of genetic variants of the endothelial Nitric Oxide Synthase (eNOS) gene and oxidative stress in the pathogenesis of nephropathy in patients with diabetes mellitus. The study included 124 diabetic patients; 68 of these patients had...
