March 2012
Determination of effective praziquantel dose in different mouse strains: BALB/c and Swiss mice in treatment of Schistosoma mansoni
Schistosomiasis is a parasitic disease, second to malaria, affecting human’s tropics and sub-tropics. The disease condition varies in severity depending on parasite species and strain, organ system infected, geographical region, genetic constitution of the individual and nutritional status. The drug praziquantel has been the choice of drug for the treatment of schistosomisias; however, the effective dose, 450...
March 2012
Job’s syndrome: A rare presentation of pulmonary Koch’s with multiple splenic abscess
Job’s syndrome is an immunodeficiency disorder with defect in leukocyte chemotaxis in some patients. It is also called hyper IgE recurrent infection syndrome. Major manifestations are pruritic dermatitis, recurrent Staphylococcal pneumonias, mucocutaneous candidiasis, restrictive lung disease, scoliosis with other various features. A 20 year old boy who was presented to us with heart failure, abdominal pain and...