June 2012

Toxicological evaluation of oregano oil

The present study evaluated the mutagenic and toxicological potential of a proprietary organic oregano/olive oil mix sold under the trade name Oreganano™. The test article was investigated for its potential to induce gene mutations according to the plate incorporation and preincubation test by Salmonella typhimurium strains TA98, 100, 1535 and 1537 and tester strain Escherichia coli WP2uvrA at...

Author(s): Palma Ann Marone, Mark Bauter, Hana Hofman-Huether, Roland J. Gahler and Simon Wood,

June 2012

Glucose-6-phosphate dehydrogenase: The balance between energy production and genetic material repair in cyanogenic toxicity response

The adult neurons are entirely dependent on aerobic metabolism involving the glycolytic pathway. The primary transport mechanism of glucose have been found to be dependent of exchange with glutamate, while the glutamate thus released is converted into glutamine by the surrounding astrocytes. In the metabolism of the glucose taken up by the neurons, glucose-6-phosphate dehydrogenase converts the glucose-6-phosphate into...

Author(s): Ogundele O. M. and Caxton-Martins E. A.,