December 2009

Anti-diabetic and some haematological effects of ethylacetate and n-butanol fractions of Ganoderma lucidum aqueous extract in alloxan - induced diabetic Wistar rats

Diabetes mellitus has become a major public health concern, especially in the developing countries. The current orthodox treatment modalities for diabetes mellitus have many drawbacks including undesirable side-effects and the high cost of long-term treatment. The aim of this study is to determine the anti-diabetic and some haematological effects of Ethylacetate and n-Butanol fractions of Ganoderma...

Author(s): A. Mohammed, A. B. Adelaiye, A. G. Bakari and M. A. Mabrouk

December 2009

Anti-hyperglycaemic, lipid lowering and anti-oxidant properties of [6]-gingerol in db/db mice

In the present study, we investigated the blood glucose lowering, lipid lowering and antioxidant effect of [6]-gingerol in type 2 diabetic db/db mice. Treatment of db/db mice with [6]-gingerol (100 mg/kg bw) for 12 days significantly (p<0.05) lowered fasting blood glucose and improved the glucose tolerance in db/db mice. Oral administration of [6]-gingerol also significantly (p < 0.05) decreased plasma...

Author(s): Amar Bahadur Singh, Akanksha, Nilendra Singh, Rakesh Maurya and Arvind Kumar Srivastava