November 2011

The molecular aspects of oral mucocutaneous diseases: A review

  Most of the mucocutaneous diseases are confined to the stratified squamous epithelium and thus may involve skin, oral and other mucosae like the nasal, ocular, genital mucosa. Some patients present with oral lesions only whereas in others there may be involvement of skin and other mucous membranes. An understanding of the basic molecular aspects of these disorders is essential for proper diagnosis. Once a...

Author(s): S. Sangeetha and Dhayanand John Victor

November 2011

The Genetic variants of IL1RAPL2 gene associated with non-specific mental retardation in Chinese children

  The present study investigated the association between the genetic variants of IL1RAPL2 gene and Non-syndromic mental retardation (NSMR) in the children of QinBa region of China. Five common SNPs (rs5962434, rs5916817, rs3764765, and rs5962298 and rs9887672) of IL1RAPL2 were chosen and examined their individual genotype frequencies using the conventional polymerase chain reaction single strand conformation...

Author(s): Zhang Kejin, He Bo, Gong Pingyuan, Gao Xiaocai, Zheng Zijian, Huang Shaoping and Zhang Fuchang,