November 2010

Tissue specificity in breast cancer: A mini review

  Cell proliferation by estrogen in the absence of BRCA1 protein may lead to a high mutation rate, thereby increasing the risk of acquiring cancer causing mutations (Scully and Livingston, 2000). The breast tissue is the target for estrogen and other hormones that are shown to endow antiapoptotic survival function upon cells sometimes in a non-autonomous manner. BRCA1 regulates DNA repair and apoptosis. In the...

Author(s): Preetha J. Shetty, Bhavani Vedicherlla, Yog R Ahuja and Qurratulain Hasan,

November 2010

Genotoxic effects of low 2.45 GHz microwave radiation exposures on Sprague Dawley rats

  This paper investigates the genotoxic effects of 2.45 GHz microwave (MW) radiation exposure at low specific absorption rates (SAR). 200 Sprague Dawley rats were exposed to SAR values between 0.48 and 4.30 W.kg-1 and the DNA of different tissues extracted, precipitated and quantified. Induced deoxyribonucleic acid (DNA) damages were assessed using the methods of DNA Direct Amplification of Length...

Author(s): M. A. Aweda, M. R. Usikalu, J. H. Wan, N. Ding and J. Y. Zhu