December 2008

Anti-inflammatory and anti-nociceptive effects of the methanolic extract of the stem bark of Ficus vallis-choudae delile (Moraceae)

The methanolic stem bark extract of Ficus vallis-choudae was investigated for anti-inflammatory and anti-nociceptive activity. The anti-inflammatory effects were investigated using rat paw edema model, while the analgesic effects were studied using acetic acid induced writhing in mice. The results obtained revealed that the methanolic stem bark extract of F. vallis – choudae  in doses...

Author(s): A. Lawan, U. A. Katsayal and A. H. Yaro

December 2008

Stability-indicating high performance liquid chromatographic determination of atorvastatin calcium in pharmaceutical dosage form

A simple, selective, precise and stability-indicating high-performance liquid chromatographic (HPLC) method of analysis of Atorvastatin Calcium in pharmaceutical dosage form was developed and validated. The chromatographic conditions comprised of a reversed-phase C18 column (250 x 4.6 mm), 5 µ with a mobile phase consisting of a mixture of Methanol: Acetonitrile: Phosphate Buffer solution in the ratio...

Author(s): Zahid Zaheer, M. N. Farooqui, A. A. Mangle A. G. Nikalje

December 2008

Antibacterial activity of leaf essential oils of Eucalyptus globulus and Eucalyptus camaldulensis

The antibacterial activities of essential oils from leaves of two Eucalyptus species (globulusand camaldulensis) was determined against Staphylococcus aureus Gram (+) andEscherichia coli Gram (-) bacteria. The inhibiting activity was evaluated by three methods: aromatogramme, microatmosphere and germs in suspension. Results   demonstrated of the leaf essential oils...

Author(s): Bachir Raho Ghalem and Benali Mohamed

December 2008

Comparison of the physical and chemical changes of magistral suspension with anesthesin and aethenamine after date of expiration

This study reports the differences in physical and chemical stability of suspension with dissolved and non dissolved main active compound. In the first case it is methenamine and the other one is anesthesin. At the same time we analyzed two fresh and two 18-months old formulations of both magistral preparations. Anesthesin suspensions did not show any significant physical or chemical changes in 18 months except changes...

Author(s): Rade Injac