African Journal of
Pharmacy and Pharmacology

  • Abbreviation: Afr. J. Pharm. Pharmacol.
  • Language: English
  • ISSN: 1996-0816
  • DOI: 10.5897/AJPP
  • Start Year: 2007
  • Published Articles: 2277

Table of Content: February 2009; 3(2)

February 2009

Pharmacognostical standardization of Commiphora berryi (Arn) Engl and phytochemical studies on its crude extracts

Commiphora genus of Burseraceae family comprises of more than 175 species. Among them many species have been reported with diverse medicinal potential.Commiphora berryi (Arn) Engl is a member of this genus and has been reported to have potential use in folklore medicine to treat various ailments such as ulcer, infection, loss of appetite etc. To supplement the necessary information for the systematic identification...

Author(s): Palanisamy Selvamani, Dhrubo Jyoti Sen and Jayanta Kumar Gupta

February 2009

Quantitative structure activity relationship studies for new antimicrobial N2- substituted phenazines

The increased availability of iminophenazines with polar substitute in the N2- side chain (notably B826 with a (3-diethylaminopropyl) imino substituent) in the spleen of mice following oral administration prompted an investigation of a possible correlation between the partition coefficient (log P) values and electronic properties expressed by s* with the concentration of the iminophenazines in the spleen of...

Author(s): M. S. Khairi Fahelelbom and  Moawia Al-Tabakha

February 2009

Pharmaceutical potentials of the oils of some popular insects consumed in southern Nigeria

Macrotermes bellicosus (MB), Imbrasia belina larva (IBL), Oryctes rhinoceroslarva (OR) and Rhynchophorus pheonicis (RP) larva oils were extracted, and the oils were physically and chemically characterized. The lipid content recorded for the insects were 31.46 ± 0.57%, 15.16 ± 0.18%, 14.87 ± 0.33% and 23.30 ± 0.33% (wet weight) for MB, IBL, OR and RP respectively....

Author(s): K. E  Ekpo, A. O Onigbinde and I. O Asia

February 2009

Antimicrobial activity and phytochemical screening of stem bark extracts from Jatropha curcas (Linn)

The in vitro antimicrobial activity of crude ethanolic, methanolic and water extracts of the stem bark of Jatropha curcas were investigated. The extracts exhibited antimicrobial activities with zones of inhibition ranging from 5 to 12, 8 to 20 and 0 to 8 mm for ethanol, methanol and water extracts respectively. The minimum inhibitory concentration (MIC) of the ethanol extract was between 0.5 and 6.25...

Author(s): O. O. Igbinosa, E. O. Igbinosa and O. A. Aiyegoro

February 2009

Anticonvulsant activity of Morinda tinctoria-Roxb

Anticonvulsant activity for Morinda tinctoria was evaluated in albino mice of either sex at 3 different dose levels (200, 400 and 600 mg/kg ip) by MES and chemical methods. The extract showed significant (p<0.001)  against both MES ( maximal electroshock) and chemical methods.   Key words: Morinda tinctoria, anticonvulsant, PTZ, MES.

Author(s): P. Thirupathy Kumaresan and A. Saravanan

February 2009

Contact toxicity of some fixed plant oils and stabilized natural pyrethrum extracts against adult maize weevils (Sitophilus zeamais Motschulsky)

The contact toxicity of some selected fixed plant oils and stabilized natural pyrethrum (Chrysanthemum cinerariaefolium) blends against adult maize weevils (Sitophilus zeamais) were investigated. Natural pyrethrum extract was stabilized against ultraviolet (UV) light by blending with fixed oils extracted from Azadirachta indica A. Juss (neem tree), Thevetia peruviana (yellow oleander)...

Author(s):  H. N. Wanyika, P. G. Kareru, J. M. Keriko, A. N. Gachanja, G. M. Kenjiand N. J. Mukiira