January 2015

Analgesic activity of Ruta graveolens L. (Rue) extracts

The knowledge of pharmacological activity is mainly derived from the use that the population makes of plants. Rue (Ruta graveolens L.) is popularly used with a degree of mysticism due to its anti-inflammatory, healing, sedative and antispasmodic characteristics. In an attempt to confirm the well-known analgesic effects, the present study evaluated Rue extracts in animal models. Two organic extracts were produced and...

Author(s): Micael R. Cunha, Tahira S. Melo, Fátima M. M. Magri and Jan C. Delorenzi

January 2015

Semantic validation of subtitles and analysis of understanding of pictograms taken from the United States Pharmacopeia Dispensing Information (USP-DI)

The aim of this study was to validate pictogram subtitles and analyze the understanding of pictograms taken from the United States Pharmacopeia Dispensing Information (USP-DI). The subtitles of 25 pictograms from the USP-DI were translated and retro-translated, and the generated subtitles were compared by two committees of judges to evaluate semantic and cultural equivalence. Semantic validity was analyzed by submitting...

Author(s): Izadora M. da C. Barros, Thaciana dos S. Alcântara, Anne Caroline O. dos Santos, Felipe P. Paixão, Germana G. de Araújo and Divaldo P. de Lyra Junior

January 2015

Extraction of resveratrol and emondin from Polygonum cuspidatum by supercritical CO2 with different solubilizers

In order to improve the extraction yields of resveratrol and emondin obtained by supercritical CO2 extraction (SCE), different solubilizers were added in the supercritical CO2 extraction process. Resveratrol and emondin were extracted from Polygonum cuspidatum by SCE with different solubilizers, including bis(2-ethylhexyl) sodium sulfosuccinate (AOT), povidone k-90 (PVP k-90), Poloxamer 188 and Tween 80, at extraction...

Author(s): Shuai He, Yong Shi, Shouyao Zhang, Zhongyi Zhang