April 2018

A systematic review: Application of in silico models for antimalarial drug discovery

Malaria remains the global public health problem due to the reemergence of drug resistance. There is an urgent need for development of new antimalarial candidates which are effective against resistant malaria parasite. This systematic review evaluates the published research studies that applied in silico modeling during the discovery process of antimalarial drugs. Literature searches were conducted using PubMed, EBSCO,...

Author(s): Anurak Cheoymang and Kesara Na-Bangchang,

April 2018

In vitro anti-inflammatory activity of Vangueria infausta: An edible wild fruit from Zimbabwe

This study set out to investigate the anti-inflammatory activity of Vangueria infausta, an edible wild fruit from Zimbabwe. The importance lies in the fact that this plant species could be developed as a low cost and effective therapeutic agent, with little or no side effects from natural sources. The fruit pulp of V. infausta was subjected to cold ethanol extraction to get crude extract. Flavonoids were isolated by...

Author(s): Luke Gwatidzo, Leo Chowe, Cexton Musekiwa and Netai Mukaratirwa-Muchanyereyi