September 2018

Acute skin irritation, acute and sub-acute oral toxicity studies of Rosmarinus officinalis essential oils in mice and rabbit

In Ankober, Northern Ethiopia, Rosmarinus officinalis has been commonly used for flavoring foods as a condiment; moreover, the plant has also been widely used for different medicinal purposes. The current study was undertaken to provide data on acute and subacute toxicity in mice as well as skin irritation of R. officinalis essential oil in rabbit. Acute dermal and oral toxicity tests were conducted using limited dose...

Author(s): Berhan Mengiste, Kassahun Dires, Ermias Lulekal,  Mahlet Arayaselassie, Tizazu Zenebe, Gezu Feleke, Eyasu Makonnen and Awol Mekonnen  

September 2018

Healing effect of the microemulsion enriched with hydroalcoholic extract of Abarema cochliacarpa (Gomes) Barneby & J. W. Grimes (Fabaceae)

Abarema cochliocarpa is an endemic plant of Brazil and has been traditionally used as a popular medicine to treat various diseases and mostly as a healing agent. The aim of this study was to evaluate the healing effect of the microemulsion containing hydrometanic fraction of the inner bark (HMF) of the plant, as well as its antioxidant, antitumor and cytotoxic potential. The cytotoxicity of HMF was assessed by the...

Author(s): Antônio Santos Dias, Clívia Rolemberg Andrade, André Luiz Lima Meneses Santos, Sabrina Zelice de Moraes, Jymmys Lopes dos Santos, Silvan Silva de Araújo, Andrea Yu Kwan Villar Shan, Jamylle Nunes de Souza Ferro, Marcelo Cavalcante Duarte, Emiliano de Oliveira Barreto, Anderson Carlos Marçal, Ricardo Luiz Cavalcante Albuquerque Júnior, Antonio Euzebio Goulart Santana, Brancilene Santos de Araújo  and Charles dos Santos Estevam