May 2011
Transient myeloproliferative disorder and hepatic failure in a newborn with Down syndrome
Approximately 10% of Down syndrome (DS) newborn develops transient leukemia (TL) also known as transient myeloproliferative disorder (TMD). Rarely, hepatic fibrosis (HF) and severe hepatic dysfunction have been reported in a patient with TL/TMD. Platelet-derived growth factor (PDGF) in combination with TGF-β1 is responsible for HF in such patients. Not only fibrosis of liver, diffuse fibrosis of other organ such as...
May 2011
Non articular synovial sarcoma of the back, a hairy nevus: An uncommon association!
Giant hairy nevus is an uncommon malformation often associated with cutaneous malignancies. Synovial sarcomas are soft tissue sarcomas that occur in the lower limb. We present our case of synovial sarcoma of the posterior trunk, its association with a hairy nevus and review literature. Key words: Synovial sarcoma, back, chromosomal translocation, hairy nevus.
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