July 2018

The amelorative effect of L-arginin and omega-3 fatty acid against sodium valproate induced hepatotoxicity

Sodium valproate (VPA) used in epilepsy and has hepatotoxic effect in mammals. This work is to assess the role of L-arginin and omega-3 fatty acid against VPA oxidative stress on liver. This study was carried out on 70 rats divided into 7 groups each of 10 rats treated orally once daily 6days/ week; Group I (control), Group II ( L-arginin): each rat was received 300 mg/kg L-arginin, Group III (omega-3): each rat...

Author(s): Dalia M. Amin, Marwa T. Abaza, Walaa M. Sarhaan, Amany I. Ahmed, Amr A. Moustafa