October 2009
The key to medicinal plants research revolves around the detection, isolation, and characterization of antioxidants as therapeutic agents
October 2009
Toxicopathological effects of Guiera senegalensis extracts in Wistar albino rats
Toxicity of methanolic and water extracts of the plant Guiera sengalensis has been tested on rats. The methanolic extract was injected intramuscularly while the water extract was given orally. Rats receiving 1000 and 500 mg/kg/day of the methanolic extract died within one week. The 250 mg/kg/day dose resulted in enlargement of the liver and kidneys, although body weights of the treated rats were not...
October 2009
Isolation of potential antibacterial and antioxidant compounds from Acalypha indica and Ocimum basilicum
In recent years multiple drug resistance has been developed in many microbes due to indiscriminate use of existing antimicrobial drugs in the treatment of infectious diseases. This paves the way for reconsidering traditional medicine; hence a study was carried out to explore the antimicrobial activities of the acetone and ethanol extract of Acalypha indica and Ocimum basilicum againstEscherichia...
October 2009
Antioxidant and antimicrobial activity of seed from plants of the Mississippi river basin
Seeds of native and naturalized plants currently found in the Mississippi River Basin of the United States were evaluated as potential new sources of antimicrobial and antioxidant activity. Methanol extracts of seeds were tested for antioxidant levels using the 2,2-diphenyl-1-picrylhydrazyl (DPPH) antioxidant assay and for antimicrobial activity using a disk diffusion assay againstStaphylococcus aureus, Pseudomonas...
October 2009
Hemidesmus indicus R. Br. root extracts reduce Salmonella typhimurium - induced inflammation in rat intestine by repressing its type three secretory proteins
Emergence of multidrug resistant bacterial strains urged the investigation for alternative medicines. The present study was designed to evaluate the mode of action of the crude methanolic extract of Hemidesmus indicus root againstSalmonella typhimurium both in vivo and in vitro. Pounded root was soaked in methanol for 7 days in room temperature with three solvent changes. The extract was pooled together,...
October 2009
Antigonadal effect induced by hydro-methanolic extract of leaf of Aegle mermelos in male rat: Effect of hCG co-administration
Antigonadal activity of hydro-methanolic (40:60) extract of leaf of Aegle marmelos was noted here by using male albino rat as model animal. This evaluation was performed by sperm count, sperm viability, sperm motility, plasma testosterone level; androgenic key enzyme activities in testis which were decreased significantly after the leaf extract treatment in respect to control. The levels of thiobarbituric acid...
October 2009
Assessment of the DPPH and α-glucosidase inhibitory potential of gambier and qualitative identification of major bioactive compound
Gambir (Uncaria gambir) and other plants belonging to the genus Uncaria have been used in traditional medicine in southeastern Asia, Africa and South America, and they have been studied widely over the past century. Gambier, the dried leaf extract from gambir is known to have antioxidant properties and some studies have attributed it to the presence of tannins and condensed tannins. The objective of this study...
October 2009
Evaluation of haematological and serum electrolyte changes in Wistar rats administered with ethanolic extract of whole fruit of Lagenaria breviflora Robert
The effect of the ethanolic extract of the whole fruit of Lagenaria breviflora Robert was evaluated on haematological indices and serum electrolyte levels of Wistar rats. 25 adult rats were randomly but equally divided into 5 groups. The rats in group A (Control) were administered with 0.9% Physiological Saline, while rats in groups B to E were administered with the extract of 1000, 2000, 4000 and 8000 mg...
October 2009
Ethnobotanical survey and preliminary evaluation of medicinal plants with antidiarrhoea properties in Sokoto state, Nigeria
Ethnobotanical survey of medicinal plants use in Sokoto state of Nigeria for the treatment of diarrhoeal disorders was conducted. The plants documented were identified botanically and ranked based on informant frequency of citation. Ten top rank plants were then selected and screened for acute toxicity, phytochemical constituents and antidiarrhoea properties. A fixed single dose (3000 mg/kg b.wt.) of aqueous extract of...
October 2009
Antioxidant and antimicrobial activities of extracts from tubers and leaves of Colchicum balansae Planchon
In this study, we examined the antioxidant and antimicrobial properties ofColchicum balansae Planchon (CB). The solvent extracts were prepared from CB tubers and leaves. In addition, free radical scavenging activities were also determined. Result of this study show that leaves extracts of CB exhibited higher antioxidant activity than tuber extracts with all types of solvent. The highest...
October 2009
Antiviral activity of Avicennia marina against herpes simplex virus type 1 and vaccine strain of poliovirus (An in vitro study)
Avicenniaceae family is a member of true mangrove plants which has one genus, 11 species and several subspecies. Avicennia marina is the most current species among these plants in Iranian mangrove forest. Regarding to the presence of many active biological constituents in this plant and their applications in traditional and alternative medicine, the in vitro antiviral activity of ...
October 2009
The postprandial effect of apple juice intake on some of the biochemical risk factors of atherosclerosis in male rabbit
Recent studies showed that high-fat meal may acutely impair endothelium-dependent vasodilation. In this study, we have investigated acute effects of apple juice intake on some of the biochemical atherosclerosis risk factors in high cholesterol fed rabbits. Rabbits were assigned to 4 groups: no cholesterol, a diet containing 1% cholesterol, a diet containing 1% cholesterol with 5 ml apple juice, a diet containing 1%...
October 2009
Anxiolytic and sedative effects of essential oil from Casimiroa pringlei on Wistar rats
The genus Casimiroa (Rutaceae) is native from Mexico and Central America,and Casimiroa pringlei (S. Watson) Engl. has been employed since prehispanic times in infusions and macerations to induce sleep and as an anxiolytic. Considering the folk use of C. pringlei, the purpose of the study was to evaluate the behavioral effects of essential oil from C. pringlei (EOCp) on an animal model....
October 2009
Anti-cancer and anti-oxidant activity of some Egyptian medicinal plants
Natural products from plants are rich sources of chemical diversity and most of the pharmacologically active principles currently used as drugs, including anticancer agents are plants products. Egypt, a semi- arid region has abundant plants resources, which are traditionally used for various disorders. The aim of the present study was to evaluate some Egyptian flora as anticancer agents. The materials used were leaves...
October 2009
Antifertility effects of ethanolic seed extract of Abrus precatorius L. on sperm production and DNA integrity in adult male mice
Abrus prectaorius L. is one of the folk medicinal plants widely used as an antifertility agent in various places of Pakistan. The aim of the present study was to investigate the antifertility activity of A. prectaorius seed extract intraperitoneally administered on sperm production and DNA integrity of spermatozoa in adult male albino mice of BALB/c strain. The daily sperm production was measured by...
October 2009
Effect of dietary supplementation with Nigella sativa L. on serum lipid profile, lipid peroxidation and antioxidant defense system in hyperlipidemic rabbits
The seeds of Nigella sativa L. (black seed) have been used as a natural remedy to treat many diseases, including hyperlipidemia in some folk medicine. Therefore, the aim of the present study was to examine the hypolipidemic and antioxidant effects of dietary black seed in hyperlipidemic rabbits. Twenty four New Zealand male rabbits were fed a 0.5% cholesterol diet for 1 month and then were randomly assigned to...
October 2009
Antisecretory and antiulcerogenic activities of the stem bark extract of Melaleuca bracteata and isolation of principles
In the present study, we have examined the effects of an ethyl acetate extract ofMelaleuca bracteata on gastric acid secretion and indomethacin-induced ulceration. The plant is popularly known for its ornamental use in South Africa. Gastric acid secretion was studied using modified method of continuous acid secretion while gastric ulcers were produced in albino rats by oral administration of indomethacin. Results...
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