Journal of Medicinal Plants Research
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Article Number - 75DA4CE41227


Vol.7(39), pp. 2885-2897 , October 2013
DOI: 10.5897/JMPR11.1657
ISSN: 1996-0875



Review

Rediscovering the medicinal properties of Datura sp.: A review


Neeraj O. Maheshwari, Ayesha Khan* and Balu A. Chopade




Institute of Bioinformatics and Biotechnology, University of Pune, Pune 411007, Maharashtra, India.


Email: sabari.dutta@gmail.com






 Accepted: 10 February 2012  Published: 17 October 2013

Copyright © 2013 Author(s) retain the copyright of this article.
This article is published under the terms of the Creative Commons Attribution License 4.0


Datura is known as a medicinal plant and plant hallucinogen all over the world. Datura has a very special place in Ayurveda since all parts of the plant namely leaves, flowers, seeds, roots, have been used for a wide range of medication such as treatment of leprosy, rabies, insanity, etc. The extract of Datura, however, is a potent poison and its indiscriminate use may lead to delirium and acute poisoning that may lead to death. The active constituents in Datura include scopolamine, atropine, hyoscyamine, withanolides (lactones) and other tropanes. Recently, withanolide compounds have shown significant antitumor, cytotoxic, anti-inflammatory, antibacterial, hepatoprotective, sedative, cytostatic and immunosuppressive activity. The present review includes phytochemical investigations and biological activities of various Datura species wherein several novel compounds have been isolated, characterized and screened for their biological activities.

 

Key words: Datura, chemical constituents, alkaloids, biological activities, therapeutic usage.


APA (2013). Rediscovering the medicinal properties of Datura sp.: A review. Journal of Medicinal Plants Research, 7(39), 2885-2897.
Chicago Neeraj O. Maheshwari, Ayesha Khan and Balu A. Chopade. "Rediscovering the medicinal properties of Datura sp.: A review." Journal of Medicinal Plants Research 7, no. 39 (2013): 2885-2897.
MLA Neeraj O. Maheshwari, Ayesha Khan and Balu A. Chopade. "Rediscovering the medicinal properties of Datura sp.: A review." Journal of Medicinal Plants Research 7.39 (2013): 2885-2897.
   
DOI 10.5897/JMPR11.1657
URL http://www.academicjournals.org/journal/JMPR/article-abstract/75DA4CE41227

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