November 2014

Evaluation of wound healing potential of different leaf extracts of Pupalia lappacea

The wound healing process is a complex and dynamic process of restoring cellular structures and tissue layers upon damage. Pupallia lappacea (L.) Juss is an annual or perennial herb of the family Amaranthaceae widespread in the tropics and sub-tropical regions and used in folklore medicine for treatment of boils, chronic wounds and skin infections. The study aims to determine the antioxidant and in vivo wound healing...

Author(s): John Antwi Apenteng, Christian Agyare, Francis Adu, Patrick George Ayande and Yaw Duah Boakye

November 2014

Saponins as immunoadjuvant agent: A review

Saponins are triterpene or steroid glycosides widely distributed in the plant and animal kingdom and include a large of number of biologically active coumpounds. Most of them have surface-active and cholesterol-binding properties. They have been shown to exhibit many biological and pharmacological activities as antiphlogistic, antiallergic, cytotoxic, antitumor and antitumor-promoting, antiviral, antihepatotoxic,...

Author(s): Antony de Paula Barbosa

November 2014

Formulation and in vitro assessment of sustained release matrix tablets of atenolol containing Kollidon SR and carnauba wax

The goal of this study was to evaluate the possibility of using Kollidon SR and carnauba wax in sustained release matrix tablets of atenolol obtained by direct compression. The compatibility between atenolol and excipients (microcrystalline cellulose, colloidal silicon dioxide, magnesium stearate, Kollidon SR, and carnauba wax) was demonstrated by differential scanning calorimetry. 100 mg atenolol tablets were prepared...

Author(s): Bianca Ramos Pezzini, Amanda Daniela Grossl, Amanda Muraro, Melissa Zétola, Giovana Carolina Bazzo and Luciano Soares

November 2014

Effect of ginger rhizome extract on lymphocytopenic guinea pig with azathioprine

The objectives of this study were to investigate quantitative alterations in leukocytes and immunosuppressive effects of ginger rhizome associated with oral administration of Azathioprine (AZA) on guinea pig model. This study was carried out at the Al Jouf University during the period from March to April 2013. A total of twelve guinea pigs randomly divided into three groups (four guinea pigs each) were used in this...

Author(s): Hassan A. Almarshad