May 2018

Dapsone in topical niosomes for treatment of acne vulgaris

Acne vulgaris is a common inflammatory skin disorder. It affects the pilosebaceous units followed by an overgrowth by Propionibacterium acne bacteria. Dapsone is a sulfone antibiotic with an anti-inflammatory effect, which is considered to be accountable for its effectiveness in the treatment of acne vulgaris. The present study aims to prepare and evaluate the effectiveness of dapsone niosomes for topical application...

Author(s): Hatem Al Sabaa, Fatma M. Mady, Amal K. Hussein, Hossam M. Abdel-Wahab and Maha H. Ragaie

May 2018

Safety and toxicity of aqueous leaf extracts of Camellia sinensis, Parquetina nigrescens and Telfairia occidentalis in mice

Plant extracts as potential phytotherapeutic products are supposed to be safe. However, adverse and untoward fatal effects have been reported.  Study aimed to evaluate the safety and toxicity of aqueous extracts of Camellia sinensis, Parquetina nigrescens and Telfairia occidentalis leaves. The extracts were subjected to brine shrimp lethality bioassay and toxicities by Lorke’s method. Mice were given oral...

Author(s): Olatunbosun Luqman Olayinka, Eltahir Awad Gasim Khalil, Atunwa S. A., Abdullaahi A. A., Salawu M. K., Ogunwale K. A. T., Olalere F. D., Lawal S. A., Abdulrafiu Majeed, Olutunde O. A., Afolabi O. O. and Nafiu A. B.