September 2017

Investigation of antihypertensive effect of Nigerian varieties of Solanum lycopersicon on rats

Hypertension remains a global challenge even in the 21st century with attendant increase in mortality rate. The quest for alternative management medications suffixed this investigation using three varieties. Thirty male hypertension induced wistar rats divided into 6 groups of 5 rats each were used. Group A served as the normal control group and was administered 0.9% normal saline as placebo. Group B, C and D were fed...

Author(s): Celestine O. Ani, Daniel C. Nwachukwu, Ene B. Chidiebere, Adugba A. Oko and Oguno C. Afam  Egharevba E. Jovita

September 2017

Administration of gentamicin-induced hematobiochemical and renal morphological alterations in Swiss albino mice

Gentamicin is widely used as an effective antibiotic. A study was conducted to investigate the effects of intramuscular administration of gentamicin on 20, 5 to 6 weeks male Swiss albino mice weighing 25 to 30 g. The mice were divided into 4 groups: Group A (kept as control); groups B, C and D (treated with gentamicin intramuscularly daily at the dose rate of 5 mg/kg for 7 days, 5 mg/kg for 30 days, and 10 mg/kg for 30...

Author(s): Nure Jannat, Nasrin Sultana and M. Rafiqul Islam