May 2016

Development of Pharmacy Education in Kenya Universities to date

The purpose of this paper was to examine the development of pharmacy education in Kenya since independence. Websites of the Pharmacy and Poison Board of Kenya and the Commission for University Education as well as those of the universities offering pharmacy education were used to obtain information such as the framework for establishment of programmes in higher institutions, curriculum, regulation of pharmacy practice...

Author(s): Ikoni J. Ogaji, Titus M. Kahiga Onesmus W. Gachuno and Julius W. Mwangi

May 2016

Biotransformation of coumarins by Cunninghamella elegans

Microbial biotransformation of coumarin (I) was undertaken using a battery of twenty five microorganisms. Among them, the fungus Cunninghamella elegans NRRL 1392 was the sole microbe that efficiently metabolized coumarin (I) into umbelliferone (II), 3, 4-dihydrocoumarin (V) and transcinnamic acid (VI). Umbelliferone was also biotransformed into 6, 7-dihydroxycoumarin (aesculetin, VII) and p-coumaric acid (VIII). On the...

Author(s): Ghadai A. Attia, Kamillia A. Abou-El-Seoud and Abdel-Rahim S. Ibrahim

May 2016

Study of the self-association of amoxicillin, thiamine and the hetero-association with biologically active compound chlorgenic acid

The self-association of amoxicillin (AMX) and its hetero-association with biologically active compound, chlorogenic acid (CGA) were investigated at room temperature (295°K). The dimerization constant of amoxicillin and thiamine (THIA) analyzed using the dimer model at the wavelength of 278 and 256 nm were found to be  and , respectively. The hetero-association constant of amoxicillin and chlorogenic acid...

Author(s): Ataklti Abraha, Alemu Kebede and Abebe Belay

May 2016

Thirst perception in mild to moderate hypertensive Nigerians treated with aqueous extract of Hibiscus sabdariffa L.

Aqueous extract of Hibiscus sabdariffa L. is widely consumed in Nigeria as a local beverage used to quench thirst and also because of its antihypertensive action. The present study investigated the effect of consumption of aqueous extract of H. sabdariffa on thirst perception (TP) in mild to moderate hypertensive Nigerians. Fifty mild to moderate hypertensive patients attending medical out-patients clinic of Enugu State...

Author(s): Nwachukwu Daniel C., Aneke Eddy I., Nwachukwu Nkiru Z., Azubike Nkiru, Obika Leonard F.O.