Journal of
Pharmacognosy and Phytotherapy

  • Abbreviation: J. Pharmacognosy Phytother.
  • Language: English
  • ISSN: 2141-2502
  • DOI: 10.5897/JPP
  • Start Year: 2009

JPP Articles in press

Article in Press

In vitro anticancer screening of Colombian plants from Piper genus (Piperaceae)

Historically, knowledge of ethnobotany, which has revealed different phytochemical and pharmacological compounds from traditional plants, have formed the basis for new anticancer drug discovery. The use of some Piper species in traditional medicine against cancer, suggest that genus Piper is a promising source of new compounds with anticancer activity. A total of 28 ethanolic extracts were obtained from 16 different Piper...

Author(s):Diego R. Muñoz, Adrián G. Sandoval, Wilman A. Delgado, Gonzalo H. Arboleda, Luis E. Cuca

Article in Press

MICROSCOPICAL, PHYTOCHEMICAL STUDIES AND ANTI-INFLAMMATORY ACTIVITY OF METHANOL EXTRACT OF Sabiceabrevipes, WERNHAM (RUBIACEAE)

Objectives: This study covers the microscopic studies, the phytochemical screening, acute toxicity evaluation and anti-inflammatory activity of the methanol extract of the leaves of Sabiceabrevipes. This plant has not been studied extensively; even when such studies were done; the focus was on the root rather than the leaf, which is easier to harvest and more abundant. Method: Free hand sections were used for anatomical...

Author(s):Michel Kenne Tchimene, Sunday Patrick Gaza Anze, Christopher Obodike Ezugwu and Maurice Mmaduakolam Iwu

Article in Press

ANTI-INFLAMMATORY PROPERTY OF THE METHANOL LEAF EXTRACT OF PARINARI KERSTINGII (ENGL) IN RATS

The Anti-inflammatory effect of the extract of Parinari kerstingii leaves was investigated using egg albumin-induced rat paw oedema, leukocyte mobilization, and acetic acid-induced vascular permeability assay methods. Heat and hypotonicity-induced heamolysis of human red blood cell membrane were also used to assess its membrane stabilizing effect and to determine its inhibitory property on phospholipase A2 activity. Acute...

Author(s):OduNwamaka Maureen,Tchimene Kenne Michel, Ogugua Victor Nwadiogu, ObongaWilfred, Sunday Patrick Gaza Anze and Nwanguma Bennett Chima

Article in Press

Comparative Proximate Composition and Hypoglycemic Properties of Three Medicinal Plants (Verononiaamygdalina, AzadirachtaindicaandMoringaoleifera).

The present study sought to investigate proximate composition in relation to the short and long term hypoglycemic effects of ethanol/water extracts of Verononiaamygdalina, AzadirachtaindicaandMoringaoleifera on hyperglycemic rats. Hyperglycemia was induced by single intra-peritoneal injection of 0.1 mol/L alloxan monohydrate in citrate buffer (pH = 4.5); dosage = 140 mg/kg; b/w.Hyperglycemic rats received separate dose of...

Author(s):Chikezie P.C and Ojiko O.A

Article in Press

Anti-inflammatory and antioxidant activity of Ixora coccinea stems

Background and objective: Ixora coccinea has mentioned in Ayurveda as Paranti and traditionally stems used in inflammatory diseases like sprains, eczema, contusions and boils. Present study deals with assessment of anti-inflammatory and antioxidant activity of extracts of I. coccinea stem. Methodology: Anti-inflammatory activity was accessed by in vivo carrageenan-induced paw edema in rat and in vitro human red blood...

Author(s):Ajaykumar Rikhabchand Surana and Rajendra Dayaram Wagh

Article in Press

Clinopodium nubigenum (Kunth) Kuntze essential oil: Chemical composition, antioxidant activity, and antimicrobial test against respiratory pathogens

The essential oil of leaves and flowers of Clinopodium nubigenum (Kunth.) Kuntze (Lamiaceae) collected in the province of Pichincha-Ecuador was steam distilled and analyzed by GC/MS to determine its chemical composition. The majority of the compounds identified were carvacrol acetate (42.1%), carvacrol (20.6%), pulegone (6.3%) and thymol (5.5%). Antioxidant activity was assessed by the assays of DPPH (IC50: 1.8 μl / ml),...

Author(s):Paco Fernando Noriega, Tatiana de Los Ángeles Mosquera, Edison Antonio Osorio, Pablo Guerra and Andrea Fonseca

Article in Press

EVALUATION OF TEA AND COFFEE PRODUCTS COMMERCIALIZED IN EGYPT

Tea and coffee have been consumed for hundreds of years for their flavour and stimulating properties. Nowadays, caffeine is receiving an increasing interest in food and pharmaceutical industries due to its central nervous system CNS stimulating properties, peripheral vasoconstriction, relaxation of the smooth muscle and myocardial stimulation. Caffeine constitutes an average of 4% of tea leaf and 1.5% of coffee bean. The...

Author(s):Hattem Mohamed Mekky

Article in Press

PHYTOCHEMICAL SCREENING AND FRACTIONATION OF Momordica charantia Linn. TO SHOW ANTIDIABETIC ACTIVITY.

Diabetes mellitus is a metabolic disorder in the endocrine system. This dreadful disease is found in all parts of the world and is becoming a serious threat to mankind health. There are lots of chemical agents available to control and to treat diabetic patients, but total recovery from diabetes has not been reported up to this date. Alternative to these synthetic agents, plants provide a potential source of hypoglycemic...

Author(s):Maninder Kaur

Article in Press

GC-MS Phytochemical Profiling and Anti-hypercholesterolemia Potentials of Cnidoscolus aconitifolius Leaf Extracts in Male Albino Rats.

The present study investigated phytochemical constituents of Cnidoscolus aconitifolius leaves extracts and its anti-hypercholesterolemia potentials using standard analytical methods. Forty five male albino rats weighing (115-121g) were used for the study. The rats were randomly divided into nine groups of five rats each. Group I served as the control while the other groups were administered 200, 400, 600 and 800mg/kg body...

Author(s):Uhegbu F.O., Chukwu E.C and Osuocha K.U

Article in Press

Fungal metagenomes in polyherbal medicines used for the treatment of tuberculosis

The traditional systems of medicine have significantly become more accepted in the developed and developing countries due to their curative property, less toxicity and minimal side effects. However, several studies have shown that they are associated with microbial contaminants. This study aimed at identifying fungi in nine polyherbal medicines used for the treatment of tuberculosis in Eastern Cape Province, South Africa....

Author(s):Elizabeth Bosede Famewo, Anna Maria Clarke and Anthony Jide Afolayan

Article in Press

Antimicrobial activity of leaf and flower extracts of Ocimum gratissimum on selected microorganisms

The antimicrobial activities of flower and leaf extract of Ocimum gratissimum obtained from the garden of the Faculty of Pharmacy and Pharmaceutical Sciences, Kwame Nkrumah University of Science and Technology Ghana, was tested against Staphylococcus aureus, Bacillus subtilis (Gram positive bacteria), Klebsiella pneumonia, Pseudomonas aeruginosa, Escherichia coli (Gram negative bacteria) and Candida albicans (fungi). These...

Author(s):Aryee Feizel Ayitey

Article in Press

Development of Validated High performance thin layer chromatography method for simultaneous determination of quercetin and kaempferol in Thespesia populnea

Thespesia populnea L. (Family: Malvaceae) is a well-known medicinal plant distributed in tropical regions of world and cultivated in south Gujarat and indicated to be useful in cutaneous affections, psoriasis, ringworm and eczema. Bark and fruits are indicated in the diseases of skin, urethritis and gonorrhea. The juice of fruits is employed in treating certain hepatic diseases. The plant is reported to contain flavanoids,...

Author(s):Hiteksha Panchal, Aeshna Amin and Mamta Shah

Article in Press

Potential of Kelakai plants (Stenochlaena palustris (Burm.F.) Bedd.) from Central Kalimantan as aphrodisiac

The necessity for traditional medicine is efficacious as aphrodisiac increases every year. Dayak community believes that Kelakai roots have efficacy as an aphrodisiac drug, but no studies were conducted relating to the efficacy of the Kelakai roots.Traditional medicinal products are efficacious as aphrodisiac have a hormone-like effect, usually contain active ingredients that have estrogenic properties among other things...

Author(s):Fahruni, Rezqi Handayani and Susi Novaryatiin

Article in Press

IN-VITRO ANTI INFLAMMATORY ACTIVITY OF GARCINIA HANBURYI EXTRACT

Garcinia hanburyi belongs to the family Clusiaceae. The whole plant was dried, extracted to obtain Xanthone rich extract. Phytochemical studies of extract showed the presence of Phenols, Alkaloids, steroids, resins and saponins. The natural sources such as a plants are an abundant source having various medicinal properties. In the present study, Garcinia hanburyi has been selected to test for the Anti-inflammatory activity...

Author(s):J. Narayanan and V.CHITRA

Article in Press

Biochemical and antibacterial activity of Jojoba Oil ‘Simmondsia chinensis’ in rats

This study has evaluated the antibacterial effect of Jojoba oil (J.O) in vivo against Staphylococcus aureus. One hundred mature male Sprague Dawley rats were divided into four groups, including the control groups and the groups treated with J.O. as part of the diet mixture (2.5% of total body weight). Our findings suggest a significant increase in body weight gain (94.0 ±5.404 g for J.O treated rats in comparison to 72.0...

Author(s):Shahd Abuhelal

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