Journal of
Pharmacognosy and Phytotherapy

  • Abbreviation: J. Pharmacognosy Phytother.
  • Language: English
  • ISSN: 2141-2502
  • DOI: 10.5897/JPP
  • Start Year: 2009

JPP Articles in press

Article in Press

PROTECTIVE EFFECT OF ETHANOLIC EXTRACT OF Cucurbita maxima (Pumpkin) LEAF ON ACETAMINOPHEN-INDUCED ACUTE LIVER TOXICITY

Ethanolic extract of dried leaves of Cucurbita maxima (Pumpkin) were screened for their phytochemical composition. The in vitro antioxidant property was determined by assessing the free radical (DPPH) scavenging activity. Twenty rats divided into four groups were used for this study with group 4 pre-treated with the extract and later intoxicated with 2g/kg single dose of acetaminophen. The hepatoprotective effect of the...

Author(s):Michael Okey Enemali, Titilayo Oluwayemisi Bamidele and Mohammed Abdullahi Ubana

Article in Press

EVALUATION OF TEA AND COFFEE PRODUCTS COMMERCIALIZED IN EGYPT

Tea and coffee have been consumed for hundreds of years for their flavour and stimulating properties. Nowadays, caffeine is receiving an increasing interest in food and pharmaceutical industries due to its central nervous system CNS stimulating properties, peripheral vasoconstriction, relaxation of the smooth muscle and myocardial stimulation. Caffeine constitutes an average of 4% of tea leaf and 1.5% of coffee bean. The...

Author(s):Hattem Mohamed Mekky

Article in Press

PHYTOCHEMICAL SCREENING AND FRACTIONATION OF Momordica charantia Linn. TO SHOW ANTIDIABETIC ACTIVITY.

Diabetes mellitus is a metabolic disorder in the endocrine system. This dreadful disease is found in all parts of the world and is becoming a serious threat to mankind health. There are lots of chemical agents available to control and to treat diabetic patients, but total recovery from diabetes has not been reported up to this date. Alternative to these synthetic agents, plants provide a potential source of hypoglycemic...

Author(s):Maninder Kaur

Article in Press

GC-MS Phytochemical Profiling and Anti-hypercholesterolemia Potentials of Cnidoscolus aconitifolius Leaf Extracts in Male Albino Rats.

The present study investigated phytochemical constituents of Cnidoscolus aconitifolius leaves extracts and its anti-hypercholesterolemia potentials using standard analytical methods. Forty five male albino rats weighing (115-121g) were used for the study. The rats were randomly divided into nine groups of five rats each. Group I served as the control while the other groups were administered 200, 400, 600 and 800mg/kg body...

Author(s):Uhegbu F.O., Chukwu E.C and Osuocha K.U

Article in Press

Fungal metagenomes in polyherbal medicines used for the treatment of tuberculosis

The traditional systems of medicine have significantly become more accepted in the developed and developing countries due to their curative property, less toxicity and minimal side effects. However, several studies have shown that they are associated with microbial contaminants. This study aimed at identifying fungi in nine polyherbal medicines used for the treatment of tuberculosis in Eastern Cape Province, South Africa....

Author(s):Elizabeth Bosede Famewo, Anna Maria Clarke and Anthony Jide Afolayan

Article in Press

Pulcandi a healing natural ashed coal against gastric acidity: scientific comprehension

As a coal, Pulcandi possesses the property of removing excess gastric and intestinal gas. Pulcandi powder has anti-diarrhea activity by decreasing intestinal fluid content and adsorbing microbes and toxins. The aim of this study was to demonstrate and to establish consequences of Pulcandi powder use on gastric acidity. For evaluating those consequences, it was investigated in vitro kinetic tests on acidity. Those tests...

Author(s):AKPALO Edéfia, ABA EKLU Gudrun, AWAGA Kwami Lumo and ABA EKLU Abatévi

Article in Press

Antimicrobial activity of leaf and flower extracts of Ocimum gratissimum on selected microorganisms

The antimicrobial activities of flower and leaf extract of Ocimum gratissimum obtained from the garden of the Faculty of Pharmacy and Pharmaceutical Sciences, Kwame Nkrumah University of Science and Technology Ghana, was tested against Staphylococcus aureus, Bacillus subtilis (Gram positive bacteria), Klebsiella pneumonia, Pseudomonas aeruginosa, Escherichia coli (Gram negative bacteria) and Candida albicans (fungi). These...

Author(s):Aryee Feizel Ayitey

Article in Press

Development of Validated High performance thin layer chromatography method for simultaneous determination of quercetin and kaempferol in Thespesia populnea

Thespesia populnea L. (Family: Malvaceae) is a well-known medicinal plant distributed in tropical regions of world and cultivated in south Gujarat and indicated to be useful in cutaneous affections, psoriasis, ringworm and eczema. Bark and fruits are indicated in the diseases of skin, urethritis and gonorrhea. The juice of fruits is employed in treating certain hepatic diseases. The plant is reported to contain flavanoids,...

Author(s):Hiteksha Panchal, Aeshna Amin and Mamta Shah

Article in Press

Potential of Kelakai plants (Stenochlaena palustris (Burm.F.) Bedd.) from Central Kalimantan as aphrodisiac

The necessity for traditional medicine is efficacious as aphrodisiac increases every year. Dayak community believes that Kelakai roots have efficacy as an aphrodisiac drug, but no studies were conducted relating to the efficacy of the Kelakai roots.Traditional medicinal products are efficacious as aphrodisiac have a hormone-like effect, usually contain active ingredients that have estrogenic properties among other things...

Author(s):Fahruni, Rezqi Handayani and Susi Novaryatiin

Article in Press

IN-VITRO ANTI INFLAMMATORY ACTIVITY OF GARCINIA HANBURYI EXTRACT

Garcinia hanburyi belongs to the family Clusiaceae. The whole plant was dried, extracted to obtain Xanthone rich extract. Phytochemical studies of extract showed the presence of Phenols, Alkaloids, steroids, resins and saponins. The natural sources such as a plants are an abundant source having various medicinal properties. In the present study, Garcinia hanburyi has been selected to test for the Anti-inflammatory activity...

Author(s):J. Narayanan and V.CHITRA

Article in Press

COMPARATIVE EVALUATION OF THE PROTECTIVE EFFECT OF LEAF EXTRACTS OF VERNONIA AMYGDALINA (BITTER LEAF) AND OCIMUM CANUM (CURRY) ON ACETAMINOPHEN –INDUCED ACUTE LIVER TOXICITY

The quest for alternate medicine in preventing and combating hepatotoxicity led to the screening of aqueous and ethanol extracts of dried leaves of Vernonia amygdalina Delile (bitter leaf) and Ocimum canum Linn (curry leaf) for phytochemicals and in vitro antioxidant properties. Some rats were pretreated with the extracts and later administered with 2g/kg of body weight single dose of acetaminophen and the hepatoprotective...

Author(s):Michael Okey Enemali and Stanley Chidi Udedi

Article in Press

Biochemical and antibacterial activity of Jojoba Oil ‘Simmondsia chinensis’ in rats

This study has evaluated the antibacterial effect of Jojoba oil (J.O) in vivo against Staphylococcus aureus. One hundred mature male Sprague Dawley rats were divided into four groups, including the control groups and the groups treated with J.O. as part of the diet mixture (2.5% of total body weight). Our findings suggest a significant increase in body weight gain (94.0 ±5.404 g for J.O treated rats in comparison to 72.0...

Author(s):Shahd Abuhelal

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