Abbreviation: J. Med. Plants Res.
Start Year: 2007
Page 1 of 172, showing 20 records out of 3427 total, starting on record 1, ending on 20
DOI: 10.5897/JMPR2015.5806[Article Number: 5CD4FBE61808]
The methanolic extract of Phyllanthus acidus pulp was screened in the present study to explore pharmacological activities on laboratory animals. The hypoglycemic activity was assessed by glucose tolerance test and the antidiarrheal activity was evaluated by castor oil induced diarrhea inhibition method. The analgesic and anesthetic activity was determined by Tail immersion method and Thiopental sodium induced sleeping... Read more.
DOI: 10.5897/JMPR2016.6272[Article Number: 95FCFA561810]
This study aims at assessing the in vitro activity of Cymbopogon citratus, Eucalyptus citriodora, Lippia multiflora, Melaleuca quinquenervia essential oils and the biobactericide Neco® on extended-spectrum β-lactamases producing or non-producing bacterial strains (ESBL) isolated at the Armed forces hospital of Libreville. The aromatogram and antibiogram were respectively assessed by the agar well diffusion... Read more.
DOI: 10.5897/JMPR2016.6259[Article Number: F3209FD61812]
Sphaeranthus bullatus aerial part is used by Chaga people in Northern Tanzania as herbal tea. It is usually drunk for the management of diarrhea. In this study acute toxicity of S. bullatus was evaluated in order to establish its safety to verify its use as herbal tea. Acute toxicity was performed per Organization for Economic co-operation and Development 423 (OECD) guideline. Six groups of female white... Read more.
DOI: 10.5897/JMPR2016.6155[Article Number: 0E2746061461]
Medicinal plants are now recognized as most important alternative for chemical drugs resource, especially for anti-microbial targets. The current study aimed to determine the scolicidal effect of Allium paradoxium and Tanacetum parthenium as medicinal plants in vitro. Protoscoleces were exposed to different concentrations of chloroformic and hydroalcholic extracts (1, 10, 50 and 100 mg/mL) for 5, 10, 30, 60 and 120 min.... Read more.
DOI: 10.5897/JMPR2016.6253[Article Number: 4E7BF1C61598]
Control of leishmaniasis remains a challenge due the high toxicity of the chemotherapeutic drugs presently available. The ongoing search for better leishmanicidal compounds has brought herbal drugs into the limelight as safe and effective substitutes to conventional therapies which have various drawbacks. The current study was designed to evaluate the antileishmanial effect of Quassia amara against Leishmania... Read more.
DOI: 10.5897/JMPR2016.6187[Article Number: 47FF22661603]
The in silico simulations and predictions approach in evaluation of pharmacokinetic properties of new chemical entities (NCEs) is fast becoming an acceptable trend in natural products research and drug discovery. This paper focuses on the properties of trolline with respect to its anti-inflammatory and MCF-7 breast cancer cell line growth inhibition effects and an attempt to predict physico-chemical drug-like properties... Read more.
DOI: 10.5897/JMPR2016.6219[Article Number: F53F0D061455]
In Bénin, malaria is a major public health concern, especially for children under five years and pregnant women. Considering the inefficiency of the health centers in some regions, people use plants for their primary health care. This study aimed to identify and document the medicinal plants used in the treatment of malaria in four departments (Littoral, Ouémé, Plateau and Zou) of south... Read more.
DOI: 10.5897/JMPR2013.5084[Article Number: 671200F61457]
The purpose of this research was to investigate the effect of crude extracts from the root of Stemona tuberosa Lour. on the replication of Autographa californica multiple nucleopolyhedrovirus (AcMNPV). Cytotoxicity of crude hexane, dichloromethane and ethanol extracts from the root of S. tuberosa was tested against Spodoptera frugiperda cell line (Sf9) using MTT assay. The cytotoxic effect, represented as CC50... Read more.
DOI: 10.5897/JMPR2016.6260[Article Number: 0D3935261459]
Several investigations have demonstrated in vitro antibacterial activity of plant extracts. Kalanchoe pinnata is globally used in folk medicine for the treatment of various diseases, such as diarrhea, infections, tuberculosis and fever. Among the enteropathogenic bacteria, enteroaggregative Escherichia coli (EAEC) is an important cause of diarrhea in the world. EAEC is also capable of forming biofilms, conformation that... Read more.
DOI: 10.5897/JMPR2016.6248[Article Number: FA8919F61413]
Artemisia monosperma (Delile) callus was induced using seedling explant cultured on Murashige and Skoog solid medium (M&S) supplemented with 1 mg/L naphthalene acetic acid (NAA) and 1 mg/L kinetin (Kn). Cultures were maintained on 2 mg/L 2,4-dichlorophenoxy acetic acid (2, 4- D) and 1 mg/L Kn and treated with different elicitors. Total flavonoids and phenolics were determined by aluminum chloride-potassium acetate... Read more.
DOI: 10.5897/JMPR2016.6207[Article Number: E010AA961417]
The cactus pear (Opuntia spp.) is known to have bioactive compounds which work in the prevention of various diseases, especially cancer. The objectives of the study were to characterize the chemical profile and genetic diversity, through chromatic tests and 1H NMR, using multivariate analysis, and assess the cytotoxic potential of cactus pear varieties of Opuntia and Nopalea genera grown in the semi-arid region of... Read more.
DOI: 10.5897/JMPR2016.6070[Article Number: 2DDB8D761340]
The species is known from Southern Nyanza, Migori in Kenya. The extraction of the stem bark was done sequentially using organic solvents starting with the least polar; n-hexane then dichloromethane, ethyl acetate and finally the most polar methanol. Antibacterial and antifungal activities of the crude extract and that of isolated compounds from the stem bark of E. excelsa were investigated. The crude extracts had... Read more.
DOI: 10.5897/JMPR2016.6094[Article Number: 441136B61343]
Calea uniflora Less. is a medicinal plant used in the treatment of inflammation and haematomas in southern Brazil. The aim of this study was to investigate the antinociceptive effects and cytotoxicity of C. uniflora. Regarding phytochemical evaluation, the crude extracts of plant were analysed by high-performance liquid chromatography (HPLC). Antinociceptive activities utilised models on chemical and thermal stimuli in... Read more.
DOI: 10.5897/JMPR2016.6193[Article Number: F521AE961346]
Herbs are used in treatment of various diseases in Uganda. Influenza is one of the diseases that is treated by herbs, the disease previously known to be non fatal is progressively becoming a threat due to immune complications in people living with HIV, poor diets and the fear of fatal introduced strains like Bird Flu. An ethno botanical survey was conducted to document medicinal plants and preparations used in the... Read more.
DOI: 10.5897/JMPR2016.6242[Article Number: 53606DE61151]
Bidens pilosa is used empirically for the treatment of various illnesses among which are: jaundice, conjunctivitis, cataract, malaria, ulcers and hypertension. This study is aimed at evaluating the sub-chronic toxicity of the leaf aqueous extracts of B. pilosa. The effects of the administration of the aqueous extracts of B. pilosa on physical (body weight, relative weight of organs), biochemical and histological... Read more.
DOI: 10.5897/JMPR2016.6249[Article Number: 7D8002861157]
Environmental factors are known to affect genes in various ways. They are affecting the gene products including the production of both primary and secondary metabolites, hence the need to assess the phytochemical and nutritional compositions of Morinda lucida Benth and Alstonia boonei De Wild growing in Nsukka, Enugu state, south eastern Nigeria. The qualitative analyses of the plant parts showed the presence of... Read more.
DOI: 10.5897/JMPR2016.6154[Article Number: 75366EA61160]
In this study, the crude methanolic extracts of whole palnt of Typha elephantina Roxb. were directed for screening of thrombolytic activity, membrane stabilizing activity, and total phenolic content. Human erythrocytes were taken for the analysis of both thrombolytic and membrane stabilizing activities and here streptokinase (SK) and acetyl salicylic acid (ASA) were used as standard for both tests, respectively. The... Read more.
DOI: 10.5897/JMPR2016.6222[Article Number: BD4B32160804]
Caryocar brasiliense (pequi) is an exotic fruit, high in monounsaturated fat acids (MUFA) and bioactive compounds, which have beneficial effects on cardiometabolic risk factors. However, this fruit is poorly studied in this context. In this study, the effects of pequi pulp intake on cardiometabolic risk factors of rats were evaluated. Therefore, 16 male weaned rats were divided into two groups: Control group and Pequi... Read more.
DOI: 10.5897/JMPR2016.6204[Article Number: 1BA8B1B60806]
Crude methanolic extracts of Crinum latifolium plant (Leaves) was assayed to identify various pharmacological properties. Antimicrobial potential of crude methanolic extracts of C. latifolium was accomplished by most commonly used disc diffusion method against a wide range of Gram positive (+ve) and Gram negative(-ve) bacteria. Extracts showed slight antimicrobial activity against Gram positive (+ve) bacteria while... Read more.
DOI: 10.5897/JMPR2016.6245[Article Number: 59CE36B60808]
Acute oral toxicity of Mystroxylon aethiopicum root bark aqueous was evaluated in albino mice of either sex. In this study, five groups of mice were orally treated with doses of 1000, 2000, 3000, 4000 and 5000 mg/kg body weight of crude extract. The mortality, signs of toxicity and body weights were observed individually for two weeks. At the end of the two weeks study, all animals were sacrificed and the hematological... Read more.
Page 1 of 172, showing 20 records out of 3427 total, starting on record 1, ending on 20