Abbreviation: J. Med. Plants Res.
Start Year: 2007
Page 1 of 176, showing 20 records out of 3518 total, starting on record 1, ending on 20
DOI: 10.5897/JMPR2017.6487[Article Number: 986804166969]
Decoctions of Persea americana Mill (Lauraceae) leaves are employed to manage diabetes mellitus among the Ibo communities of Eastern Nigeria. In this study, we studied the ameliorative effects of the aqueous extract of P. americana leaves (AEPAL) on alloxan-induced hyperglycaemia and hyperlipidaemia in Wistar rats. The oral median lethal dose (LD50) of AEPAL was determined in rats. The effects of extract on blood... Read more.
DOI: 10.5897/JMPR2017.6519[Article Number: F43165A66970]
Resistance of malaria parasites to several antimalarial drugs mandates the need for new compounds from affordable sources. Thus the current study was conducted to justify the traditional usage of Lantana trifolia roots and Premna oligotricha leaves to combat malaria. The powdered roots of Lantana trifolia and leaves of Premna oligotricha were macerated using 70% ethanol. Secondary metabolites present... Read more.
DOI: 10.5897/JMPR2017.6527[Article Number: 85F2CC166882]
Traditional medicine is widely used, but its effectiveness is often questioned. Biofilm-producing bacteria and fungi are important in difficult-to-treat persistent and recurrent infections. The present study investigated the anti-biofilm properties of crude methanolic extracts from three medicinal plants used in Namibia, namely Aptosimum albomarginatum (Marloth and Engl.), Albizia anthelmintica (A. Rich Brongn.) and... Read more.
DOI: 10.5897/JMPR2017.6484[Article Number: 055AE2D66886]
Watermelon [Citrullus lanatus (Thunb) Matsum and Nakai] is rich in vitamins C and B complex, and the red color of its pulp is due to the presence of lycopene. Lycopene is an antioxidant component and it is able to neutralize free radicals especially responsible for skin aging. Thus, a formulation containing lycopene extracted from watermelon was developed, and its physical-chemical stability and in vitro antioxidant... Read more.
DOI: 10.5897/JMPR2017.6512[Article Number: 4A3FF2F66877]
Research into ancient cultures has yielded a large body of evidence on the use of medicinal plants for preventive and/or therapeutic purposes. Such plants may have many metabolic activities and functions in the body-antioxidant, anti-inflammatory, platelet aggregation inhibitory and immunological and they can act at different molecular levels. This work offers a comprehensive review of research into the phenolic profile... Read more.
DOI: 10.5897/JMPR2017.6494[Article Number: 6EC6B9E66879]
Cola acuminate is one of the three edible forms of bizzy nut that has been used for medicinal and therapeutic purposes. However, the precise compound responsible for its biological effects has not been completely identified. Using sequential solid--liquid extraction of bizzy nut coupled with bioactive screening, ether extract was obtained (Biz-2) and it possesses tumor inhibitory activity specific for prostate cancer... Read more.
DOI: 10.5897/JMPR2017.6492[Article Number: D0CB45366820]
The rapid iterative negative geotaxis (RING) assay is a commonly used behavioral test in Drosophila based on digital imaging of flies and requires minimal equipment and space. Larval mobility can be used to reliably determine the effect of drugs on locomotion in Drosophila larvae. The effects of Valeriana officinalis extract (VoE) and melatonin (ME) were tested in Drosophila melanogaster flies and larvae. In the RING... Read more.
DOI: 10.5897/JMPR2017.6390[Article Number: 422BD7166673]
In this study, the ability of Tinospora crispa aqueous extract (TCAE) to regulate cholesterol metabolism in human hepatoma cancer cell line (Hep G2) was determined. Cytotoxic study was performed by exposing hepatoma cell (Hep G2) towards TCAE with concentration ranging from 0.002 to 20 mg/ml for 24 h at 37°C and with 5% CO2 atmosphere. Result revealed that TCAE was not toxic to the cell. The ability of TCAE to... Read more.
DOI: 10.5897/JMPR2017.6510[Article Number: 29F933866677]
Due to widespread bacterial resistance to commercial antibiotics, the search for capable substances to combating these microorganisms became a priority. In this context, the endophytic fungi gained prominence as potential producers of bioactive substances with pharmacological interest. It is considering that endophytes are still poorly studied, especially in tropical species. The antibacterial and antifungal potential... Read more.
DOI: 10.5897/JMPR2017.6471[Article Number: 047055E66685]
Ephedra is likely one of the oldest medicinal plants still currently in use. In folk medicine, extracts of Ephedra foeminea are commonly used to treat cancer patients. In relation to its traditional use, the aim of the present study was to determine the cytotoxic activity in vitro of E. foeminea extracts on cancer and non-cancer cells. Cell viability was determined using XTT assay, induction of apoptosis by cell sorting... Read more.
DOI: 10.5897/JMPR2017.6469[Article Number: 5D8BBAE66600]
Pentadesma butyracea is a rainforest species of Clusiaceae family with multi-values for human healthcare according to previous ethnobotanical survey. In spite of this traditional use of P. butyracea, there is a lack of scientific knowledge of its biological activities. Therefore, the aim of this study was to identify the major phytochemical compounds of P. butyracea hydroalcoholic seeds extract and to assess... Read more.
DOI: 10.5897/JMPR2017. 6506[Article Number: 022EBDE66602]
Momordica charantia has been used traditionally for the treatment of several ailments. Some natural plant products are known to exhibit cytotoxic or anti-proliferative effects on cancer cell lines, such plants offer a promising therapeutic approach as an anti-tumor agent. In this study, the anti-proliferative effects of graded concentrations of methanol leaf extract of M. charantia (MEMC) at different point time was... Read more.
DOI: 10.5897/JMPR2017.6465[Article Number: 0E62B6566504]
A protocol for large-scale in vitro production of Baccharis myriocephala was developed. Total phenolic content was analyzed in plants cultured on MS + 1.0 mg.L-1 of indoleacetic acid (IAA), benzyladenine (BA) or kinetin (KIN). Nodal segments obtained from seeds germinated in vitro on Murashige and Skoog basal medium (MS) were subcultured on MS basal medium, hormone-free or with different growth regulators added: IAA, BA... Read more.
DOI: 10.5897/JMPR2017.6505[Article Number: 9974DA766506]
Amburana cearensis is a medicinal plant widely used in folk medicine. The purpose of this study was to identify the more appropriate extraction solvent for maximum antioxidant and antimicrobial effect. The extraction of A. cearensis seeds were carried out gradually to obtain the highest yields and constituents of the extracts using as solvent hexane, methanol, 80% alcohol and water in this sequence. Phytochemical... Read more.
DOI: 10.5897/JMPR2017.6485[Article Number: 854FF7566460]
The Vietnam-Laos International Cooperative Biodiversity Group (ICBG) based at the University of Illinois at Chicago (UIC) catalyzed a country-wide network of medicinal plant preserves (MPP) and medicinal biodiversity preserves (MBP) now established in ten provinces of the Lao People’s Democratic Republic (Lao PDR), which are relied upon as protected sources of ethnomedicines for local villagers and traditional... Read more.
DOI: 10.5897/JMPR2017.6460[Article Number: B944C7166462]
In this study, the chemical composition of the peel and pulp of Mauritia flexuosa fruits were analyzed and the antimicrobial activity of ethanolic extracts from these fruits was evaluated using in vitro tests. Chemical composition analysis with gas chromatography-mass spectrometry (GC-MS) indicated the presence of saturated and unsaturated fatty acids. The peel extracts (ECBU) presented 54.41% and the pulp (EPBU)... Read more.
DOI: 10.5897/JMPR2017.6468[Article Number: 144530266319]
The aim of this study was to evaluate the chemical composition and antimicrobial activity of four unexplored Eugenia species: Eugenia brevistyla, Eugenia handroana, Eugenia catharinae and Eugenia stigmatosa. Eight extracts and eighteen fractions were screened for their antibacterial activity against some selected bacteria including Mycoplasma. Phytochemical screening revealed that the plants were rich in terpenes and... Read more.
DOI: 10.5897/JMPR2017.6436[Article Number: 1349A8666324]
Eugenia uniflora L. (Myrtaceae) is popularly known in Brazil as pitanga or ibitanga. The infusion of E. uniflora leaves is being used in folk medicine as anti-diarrheal. The present study sought to evaluate the gastroprotective potential of the aqueous fraction of hydroacetonic leaf extract of pitanga (AFHP). The leaf powder of pitanga was extracted with 50% acetone using an overhead stirrer apparatus at room... Read more.
DOI: 10.5897/JMPR2017.6479[Article Number: E9188BD66329]
The present study seeks to evaluate the immunoregulatory effects of extracts of the root bark of Cassia sieberiana, a plant used in Ghana for various painful inflammatory conditions, in a modified adjuvant arthritis model induced by administration of very low dose of Mycobacterium tuberculosis (MT) – carrageenan mixture in the rat. A volume of 0.1 mg kg-1 heat killed MT in paraffin oil was mixed with equal volume... Read more.
DOI: 10.5897/JMPR2017.6457[Article Number: 9D7CDE566303]
New therapies for leukemia are urgently needed due to adverse side effects, tumor resistance and lack of selectivity of many chemotherapeutic agents in clinical use. Ageratum conyzoides has been used in folklore medicine for managing leukemia and other cancers. Thus, this study aimed to investigate the effects of fractions, sub-fractions and purified compounds from the ethanol leaf extracts of A. conyzoides against... Read more.
Page 1 of 176, showing 20 records out of 3518 total, starting on record 1, ending on 20