Journal of
Medical Laboratory and Diagnosis

  • Abbreviation: J. Med. Lab. Diagn.
  • Language: English
  • ISSN: 2141-2618
  • DOI: 10.5897/JMLD
  • Start Year: 2010

JMLD Articles

June 2018

Prevalence of Smear positive Pulmonary Tuberculosis (PTB) and Associated Factors among PTB Suspects Attending Harar Tuberculosis Control Center, Harar, Ethiopia

Tuberculosis (TB) continues to be an important public health problem worldwide. It is a leading cause of disability and death in many parts of the world especially in the developing countries. Ethiopia has already a record of history of TB around greater than 58 years. The aim of the study was to determine the prevalence and associated factors of pulmonary tuberculosis (PTB) in Harar TB control center. A health...

Author(s): Hylemariam Mihiretie, Daniel Getacher, Yaregal Araya, Diriba Gemechu, Eskedar Taye and Berhanu Seyoum  

June 2017

Health professionals’ stance towards medical laboratory technology: A cross-sectional study

The practice of modern medicine would be impossible without the tests performed in the clinical laboratory. In today’s era of rapidly evolving medical research and application, medical laboratory technology plays an integral role in the health care system. In spite of this, the propensity of giving less value to the profession by certain health practitioners might reduce the health team mobilization which...

Author(s): Awoke Derbie and Daniel Mekonnen

February 2017

Seroprevalence of Rubella virus among pregnant Sudanese women with history of abortion

Mainly, rubella infections during pregnancy are considered as serious infections worldwide. Since Rubella virus not only infects susceptible women early in pregnancy, they can also be transmitted to the fetus, and might induce birth defects. Accordingly, accurate as well as meticulous diagnosis of rubella infection is crucial during pregnancy. A descriptive, retrospective cross sectional hospital based study was...

Author(s): Bahaeldin K. Elamin, and Nagi Bushra Khidir

January 2017

Quality analysis of the preanalytical phase of laboratory tests: Case of the civil hospital (Tetouan–Morocco)

Several studies report that between 60 to 85% of laboratory errors are produced during the preanalytical phase. The objective of this study was to identify the factors at the origin of nonconformities during this phase at the Civil Hospital of Tetouan. A mixed preanalytical descriptive study realized between April and May 2014 was based on a questionnaire, an observation grid, focus groups and semi-structured...

Author(s): Chemao-Elfihri, Wafa, Moussaoui M., Firsiwi K., Jbari B. and El Morhit M.

December 2016

Assessment of antimicrobial susceptibility testing techniques in some laboratories in Cameroon

The increasing bacterial resistance to antimicrobial agents has rendered susceptibility testing an indispensable tool for appropriate antibiotic selection. This study is aimed at evaluating the technical methods of antibiogram in some medical laboratories in Cameroon. A descriptive cross-sectional study was carried out. The data collection was done with two material, the questionnaire and the observation sheet. We...

Author(s): Tchoula Mamiafo Corinne, Gonsu Kamga Hortense , Toukam Michel, Emilia Enjema Lyonga-Mbamyah, Andremont Antoine.

September 2016

Blood group serology analysis of one rare case of β-thalassemia major with cold autoantibodies and alloantibodies

β thalassemia major is one of major public health problem in south China requiring lifelong blood transfusions for the children to stay alive. However, long-term transfusion increases the risk of the patients to produce the autoantibodies and alloantibodies due to repeated exposure to foreign antigens. In this study, we reported one rare case of β-thalassemia major with cold autoantibodies and alloantibodies....

Author(s): Zhi-xin Song and Yong Zou

September 2016

Teratocarcinosarcoma of the tongue with bilateral neck nodal metastases

When confronted with a tongue and neck mass in a child, a specific diagnosis can be difficult to make with a differential diagnosis often provided. Teratocarcinosarcoma of the tongue with metastases to the neck would be considered an extremely rare specific diagnosis to correctly make prospectively. This study presents the clinical appearance, as well as the CT, MRI, PET and pathologic findings in this rare entity. With...

Author(s): Peter Kalina, Erik Steckler and Heidi Lehrke

May 2016

Prevalence and associated risk factors of Hepatitis B and Hepatitis C virus among volunteer blood donors in Arba Minch Blood Bank SNNPR, Ethiopia

Hepatitis B virus (HBV) and Hepatitis C virus (HCV) is major public health problems that affect million people worldwide and people who are infected assumed to develop liver cirrhosis or hepatocelular carcinoma. Screening of blood donors is essential for healthy and safe donation. A cross sectional study design was conducted among volunteer blood donors in Arba Minch blood bank from March 2015 to April 2015. A total of...

Author(s): Ayele Adato kabato and Gebru Mulugeta Weldearegay

April 2016

Development of an algorithm of haematologic parameters as surrogate markers for CD4 cell count in resource-limited settings

Total Lymphocyte Count (TLC) has been previously evaluated as a surrogate for CD4 counts in the management of HIV especially in resource-limited settings with varying results. This study developed a clinical algorithm of TLC and other significant haematologic parameters to raise the predictive value of TLC in classifying subjects with CD4 count <350 cells/mm3. Total samples of 215 HIV-seropositive ARV-naïve...

Author(s): Agwata Diana Kwamboka, Ongus Juliette, Mbugua Amos, Peter Maturi, Nyamari Jackim and Uwamungu Schifra

March 2016

Safety of collagen and reticulin fibres in the liver and kidney of broiler chicken fed with Aspergillus niger -hydrolyzed cassava peel meal as carbohydrate source

Cassava peels which is available in large quantity as waste is being considered as a possible replacement for maize in chicken feeds due to the world shortage of cereals. This study examined the safety of collagen and reticulin fibres in the liver and kidney of broiler chicken, when the Aspergillus niger-hydrolyzed cassava peel meal (HCPM) was used as diet carbohydrate. HCPM was used as replacement for maize in chicken...

Author(s): Muhammed Abdurrasheed Ola, Adeyemo Isiah Adeyemi, Olutunde  Oluwumi Abiola, Afodun Moyosore Adam and Ajayi Ayooye Samuel

January 2016

High prevalence of gallbladder involvement during hepatitis: An outbreak in a paediatric population

Acute hepatitis A (AHA) in children usually has generally benign course. In literature, there are several descriptions of gallbladder involvement in AHA, but there are few data on the pediatric population. Fifteen children living in a Romani camp or in the neighbourhoods with AHA were admitted. 57% of children who underwent abdomen ultrasounds showed a significant gallbladder involvement and none of the patients...

Author(s): Vita S., Tebano G., Rossomando A. M., De Rosa A., Cavallari E. N., Caraffa E., Ajassa C. and Vullo V.

October 2015

Plasma von Willebrand factor level and its associated parameters: Reference ranges in Nigeria

Von Willebrand factor (VWF) is a complex multimeric, multifunctional glycoprotein. It plays a primary role in haemostasis by forming platelet plugs at sites of vascular injury. The biological breakdown of VWF is mediated by a metalloprotease, ADAMTS-13. Both proteins are important in normal coagulation. Deficiencies in gene and or protein of VWF are associated with von Willebrand disease and those of ADAMTS-13 are...

Author(s): Eyiuche D Ezigbo, Ernest O Ukaejiofo and Ijeoma Chinyeaka

September 2015

A novel method for reducing human pipetting errors

Human errors in clinical and research laboratories constitute a substantial source of lost productivity. Here we present a novel method for reducing human errors in pipetting by providing real time feedback to the laboratory worker. The system uses light emitting diodes to indicate wells that have been accessed for pipetting using a system that is based on Faraday’s principle of electromagnetic induction.This...

Author(s): Kyle Lyman, Daniel Fisher, Ye Han and Dane M. Chetkovich

August 2015

Evaluation of quality management systems implementation in medical diagnostic laboratories benchmarked for accreditation

Accreditation is the process which ensures that certification practices are implemented in laboratories to enhance their quality and efficiency. It in turn helps laboratories to improve technical processes, achieve competitive advantage and increase market share. To achieve accreditation, successful implementation of the laboratory quality management system (LQMS) is a requisite. In this study, evaluation of quality...

Author(s): Tamil Selvi Manickam and Srinivas Ankanagari

May 2015

Prevalence of occult hepatitis B virus (HBV) infections in haemodialysis patients in Khartoum State, Sudan from 2012 to 2014

This study was carried out to detect occult hepatitis B virus (OHB) among haemodylsis patient in Khartoum State, Sudan. Antigen capture enzyme linked immunosorbent assay (ELISA) to detect hepatitis B surface antigen (HBsAg), competitive ELISA to detect Hepatitis B core antibody (HBcAb) antibodies and polymerase chain reaction (PCR) to detect hepatitis B virus (HBV) DNA were used to analyze 100 plasma samples collected...

Author(s): Abdalhafeez A. Mohammed, Khalid A. Enan, Osama M. Khair , Mohammed O. Hussien, Abdel Rahim M. El Hussein and Isam M. Elkhidir  

April 2015

Seroprevalence of herpes simplex virus 2 infection among pregnant women in urban health training Yopougon-Attie (Cote D’ivoire)

The seroprevalence of herpes simplex virus II (HSV2) was investigated from April, 2011 to May, 2012 among 170 pregnant women attending consultation in the urban health training Yopougon-Attié, Abidjan (Côte d'Ivoire). The anti-HSV2 immunoglobin G (IgG) antibodies were detected by the principle of indirect enzyme-linked immunosorbent assay (ELISA) using the Diagnostic Automation ELISA® kit. Human...

Author(s): Boni Cisse C., Zaba, F., Meite, S., Mlan, A., Inwoley, K., Kouassi M’Bengue, A., Sevede, D., Faye Kette, H., and Dosso, M.,

February 2015

Review on convectional and advanced diagnostic techniques of human tuberculosis

Tuberculosis is a major health problem throughout the world causing large number of deaths, more than that of any other single infectious disease. Accurate and early diagnosis of tuberculosis is important for its effective management. The continued development of affordable, sensitive, and specific diagnostic tools will be required for use in resource-poor settings, where the incidence of disease is the highest like...

Author(s): Tadesse Birhanu and Eyasu Ejeta

January 2015

Evaluation of Sysmex UF-1000i and Alifax Alfred and HB&L in rapid diagnosis of acute urinary tract infections in a hub and spoke setting

This paper compares, in a hub and spoke (H&S) setting, the performance of two automated methods in rapid diagnosis of urinary tract infections (UTI). 2335 midstream urine samples obtained from adult patients were considered. In the spoke laboratory, rapid diagnosis of UTI was performed by using bacteria quantification with a Sysmex UF-1000i analyzer. In the hub laboratory, rapid diagnosis of UTI was performed by...

Author(s): Gianluca Gessoni, Francesco Antico, Maria Solinas, Sandra Mazzucato, Sara Valverde, Francesca Gessoni, Marta Grandesso and Stefano Grandesso  

September 2014

Screening for hemoglobinipathy in Beja tribes and other minor groups living in Port Sudan City

Hemoglobinopathies prevalence and distribution among ethnic groups inhabiting the Red Sea State in Sudan were not reported till date. Accordingly, this study has been conducted to address this problem in that area. The study was a cross-sectional descriptive one conducted in Port Sudan city to screen for hemoglobinopathy in anaemic patients referred to three major centers. The study population included 209 patients, 54%...

Author(s): Mohammed Omer Gibreel, Mubarak El Saeed Elkarsani, Munsour Mohammed Munsoor and El Yasaa Ahmed Gubartella

May 2014

Reactive thrombocytosis and erythrocyte sedimentation rate in patients with pulmonary tuberculosis

This study aimed at assessing the reactive thrombocytosis and erythrocyte sedimentation rate in patients with pulmonary tuberculosis living in Port Sudan City, Red Sea State, Sudan. This study covers the period from June 2006 up to December 2008 at Port Sudan Tuberculosis Diagnostic Center. Hundred newly discovered Ziehl Neelsen stain positive males (77%) and females (23%) were randomly selected to be the study sample...

Author(s): Bashir A. B., Ageep Ali K, Abufatima A. S. and Mohamedani A. A.

February 2014

Laboratory diagnostic systems used in the diagnosis of tuberculosis in Ethiopia: A systematic review

Laboratories and laboratory tests are fundamental components of tuberculosis control programme; providing testing for diagnosis, surveillance and treatment monitoring at every level of health care system. This review is therefore, aimed at comparing and summarizing data on these laboratory systems used in the diagnosis of tuberculosis in Ethiopia. A systematic review of literature addressing the diagnosis of...

Author(s): Addisu Melese Dagnaw and Balew Zeleke Tiruneh

February 2014

Total and CD4+ T- lymphocyte count correlation in newly diagnosed HIV patients in resource-limited setting

Few clinical settings in resource-limited countries perform CD4+ T-lymphocyte counts required as a baseline test for antiretroviral therapy. We investigated CD4 count in newly diagnosed HIV-infected patients attending our treatment centre and evaluated suitability of total lymphocyte count (TLC) as a surrogate marker for CD4+T-lymphocyte count required as a yardstick for initiating antiretroviral therapy. Usefulness of...

Author(s): Fasakin KA⊃, Omisakin CT⊃, Esan AJ⊃, Adebara IO⊃, Owoseni IS⊃, Omoniyi DP⊃, Ajayi OD⁴, Ogundare RG⁵ and Moronkeji MB⁶

January 2014

Aberration of French Public Health Authorities policies for the cost-assessment of microbiological diagnosis in ophthalmology

Sensitive and specific laboratory tests adapted to ophthalmologic micro specimens are necessary for the clinical management of corneal ulcers (CU). The goal of this work is to analyze the correlation of diagnosis tests specificities with pricing policies for public laboratories. Human specimen procedures were extracted from the National Eye Center Laboratory registers in Paris, France with reimbursement values (pricing)...

Author(s): Pablo Goldschmidt, Lilia Merabet, Florence Daban, Laurence Batellier, Edgard Benveniste and Christine Chaumeil

January 2014

Risk analysis and management of non-conformities of the pre-analytical phase in a university testing laboratory of bacteriology

Due to the great deal of attention given to patient’s security, it is necessary to reduce non-conformities in pre-analytical phase, so the laboratories of medical bacteriology that can ensure the quality of examination results can contribute to diagnosis and prescription of treatment and patient safety. It is important that these laboratories collect and exploit statistics of the non-conformities rates which occur...

Author(s): Youssef El Hani, Hafsa Lamrani Alaoui, Najat Mahassini, Leila Radi, Mimoun Zouhdi and Abdelkarim Filali-Maltouf    

November 2013

Endemicity of schistosomiasis in some parts of Anambra State, Nigeria

Investigation on the prevalence of infections with schistosoma was carried out amongst inhabitants of two local government areas (LGAs), Nigeria between October 2007 and September 2008. A total of 2064 randomly selected subjects had their urine and stool samples examined for eggs of Schistosoma and 323 (15.7%) were excreting eggs of S. haematobium in their urine with geometric mean egg count (GMEC) of 10.1 eggs/10 ml of...

Author(s): Dennis O. Ugochukwu, Celestine O. E. Onwuliri, F. O. U. Osuala, Ikechukwu N. S. Dozie, F. N. Opara and Ucheamaka Chinenye Nwenyi

November 2013

Evaluation of SD BIOLINE rapid antibody test for diagnosis of Helicobacter pylori infection

Helicobacter pylori infection is most prevalent and known to cause chronic gastritis and peptic ulcer disease in Ethiopia. To date, simple and rapid point-of-care tests are commercially available; however, information is limited regarding their diagnostic significance. This cross-sectional study was conducted to evaluate the diagnostic performance of SD BIOLINE H. pylori rapid antibody test. A consecutive 203 enzyme...

Author(s): Endale Tadesse, Gebru Mulugeta and Techalew Shimelis

October 2013

Seroprevalence of cytomegalovirus infection among pregnant women at Omdurman Maternity Hospital,Sudan.

This study was conducted to determine the seroprevalence of human cytomegalovirus (HCMV) among pregnant women at Omdurman Maternity Hospital between the period January 2009 and June 2009. Descriptive cross-sectional study was conducted in Omdurman Maternity Hospital; blood was taken from pregnant women that came for delivery and investigated for cytomegalovirus specific immunoglobin G (IgG) and immunoglobin M (IgM)...

Author(s): Khairi S. I., Intisar K. S., Enan K. H., Ishag M. Y., Baraa A. M. and Ali Y. H.

October 2013

Towards the development of rapid biofilm antibiotic sensitivity testing (BAST)

This study presents a modification of the antibiotic susceptibility testing (AST), which is a rapid means of determining the response of planktonic bacteria to different antimicrobial agents, for application to biofilms. Colony biofilm was first developed on a cellulose filter/membrane disc, over which an antibiotic disc was imposed. Zone of inhibition was measured after incubation on nutrient agar. Biofilms were not as...

Author(s): AL Quthami Khalid, Bassam O. AlJohny and Milton Wainwright

August 2013

Improving the case detection of pulmonary tuberculosis by bleach microscopy method in the North West of Nigeria

Microscopy of direct smears for acid-fast bacilli (AFB) remains the common method for the laboratory diagnosis of pulmonary tuberculosis in most laboratories in our setting. The bleach microscopy method has been introduced and evaluated in different settings as an alternative to direct smear microscopy. However, this approach is yet to be evaluated in a typical government owned/public health laboratory in our setting...

Author(s): Ameh James, Shuaibu Uba Abba, Aminu Ibrahim, Henry Mbah, Humphrey Musuluma, Kingsley Ochei, Saffiatou Darboe and Kwasi Torpey

August 2013

Haematologic and biochemical indices of Plasmodium falciparum infected inhabitants of Owerri, Imo State, Nigeria

In spite of threats malaria pose to public health, specific records on alterations in some haematologic and biochemical indices of inhabitants of Owerri Municipality infected with P. falciparum malaria have not received wide reports and documentation. Accordingly, the present study sought to investigate alterations in haematologic and biochemical indices of moderately P. falciparum infected male...

Author(s): Chikezie Paul Chidoka and Okpara Richard Tochukwu

July 2013

Prevalence of zinc-α 2-glycoprotein binding peptide among Omani blood donors

Zinc alpha-2-glycoprotien (ZAG) binding peptide is a multi-functional protein, which is structurally similar to a major histocompatibility complex class I. It has been discovered as a novel adipokine enhancing lipolysis and influencing other physiological processes such as sperm mobility and melanin production. Furthermore, ZAG level has been correlated to a variety of diseases such as atherosclerosis and diabetes type...

Author(s): Hasson, S. S., Al-Balushi, M. S, Al Shaili, A. S, Al-Busaidi J. Z., Said, E. A.,Idris, M. A. and Al-Jabri, A. A.

July 2013

Role of oxidative stress in aggravating kidney dysfunction in coronary artery disease patients- A laboratory finding

Acute cardiac decompensation results in activation of hemodynamic and neurohormonal factors that lead to an acute drop in glomerular filtration rate (GFR) resulting in acute kidney injury. This relationship is referred to as cardiorenal syndrome type 1 (CRS), which usually goes unnoticed. The present study was designed to evaluate the occurrence of kidney dysfunction in coronary artery disease (CAD) patients visiting...

Author(s): Ritu Sharma and Mridula Mahajan

February 2013

Acute respiratory distress syndrome secondary to High-altitude pulmonary edema: A diagnostic study

High altitude pulmonary edema (HAPE) is the most common of the serious manifestations of altitude sickness, acute respiratory distress syndrome (ARDS) may be secondary to HAPE in some severe cases. The purpose of this study was to evaluate the diagnosis of ARDS at an altitude above 4000 m. Clinical studies were performed in eight patients with ARDS secondary to HAPE at an altitude of 4500m, 10 patients with pure HAPE...

Author(s): Si Qing Ma, Tian Yi Wu, Qiang Cheng, Pei Li and Hui Ping Bian

February 2013

Serum levels of glycosaminoglycans (GAGs) and insulin like growth factor-1 (IGF-1) as diagnostic markers for early hepatocellular carcinoma in cirrhotic patients with or without diabetes

The significance of serum levels of glycosaminoglycans (GAGs) and insulin like growth factor-1 (IGF-1) in early screening of hepatocellular carcinoma in cirrhotic patients was evaluated. The effect of diabetes on GAGs and IGF-1 levels was also estimated. Fifty cirrhotic patients with early stage Hepatocellular carcinoma (HCC) (22 were diabetic), thirty control cirrhotic patients without HCC (11 were diabetic) and twenty...

Author(s): Ahmad S. Ibrahim, Hala A. Attia, Ahmad M. Rabea and Amal M. El-Gayar

November 2012

Laboratory diagnosis of malaria: Comparing giemsa stained thick blood films with rapid diagnostic test (RDT) in an endemic setting in North-west Nigeria

Malaria microscopy will continue to remain the gold standard for the diagnosis of malaria, but prolonged turnaround time and lack of malaria microscopist that are associated with this technique continue to impact on the quality of service rendered by the laboratory, especially the turnaround time, which is one of the quality indicators to measure laboratory quality systems. The prolonged turnaround time and lack of...

Author(s): James Ameh, Rakiya Muhammad Ahmad, Nelson Ekeh, Pussam Linga, Zirra Mangoro, Asiya Umar Imam, Peter Akeredolu and Shuaibu Hudu

November 2012

Percutaneous needle biopsy in the diagnosis of soft tissue tumors – A potent tool in underdeveloped countries

Fine needle aspiration biopsy is a useful tool in the pre-operative evaluation and grading of soft tissue tumors, and offer patients the advantage of neo-adjuvant/ adjuvant chemotherapy or radiotherapy. Our study aimed at correlating the clinical, radiological and cytological findings of benign and malignant tumors of soft tissues and evaluating the usefulness of percutaneous needle biopsy as a diagnostic tool. Out of a...

Author(s): Jaseem Hasan, S. Shamshad Ahmad, Kafil Akhtar, Shaista M. Vasenwala and Mehar Aziz

February 2012

Self-test monitoring of the Th1/Th2 balance in health and disease with special emphasis on chronic fatigue syndrome/myalgic encephalomyelitis

A simple “self-test” principle is described which allows patients to evaluate their Th1/Th2 balance repeatedly over short periods of time to follow-up the effects of taking pre- and probiotics, neutraceuticals, drugs or any other therapeutic strategy to balance Th1/Th2 status. By analysing a large number of first morning urine samples obtained from individuals with medical conditions associated with an...

Author(s): Chris Roelant and Kenny De Meirleir

February 2012

Assessment of ethical and other professional standards in private medical laboratories: Osun State experience

Compliance of private medical laboratories in the state with ethical and other professional standards as prescribed by the Medical Laboratory Science Council of Nigeria (MLSCN) was assessed by the researcher’s pre and posts the inspection by the MLSCN. Laboratory environment, personnel, equipment and adherence to Standard Operating Procedures (SOPs) were used as indicators and results obtained were compared. 13/21...

Author(s): Muhibi M. A., Hassan A. O. and Muhibi M. O.

October 2011

A diagnostic dilemma-endodontic lesion or keratocystic odontogenic tumor (KCOT): A case report

We present a case of keratocystic odontogenic tumor (KCOT) in maxillary canine region which was mistaken for a periapical lesion and was treated accordingly that is, root canal treatment of the teeth involved, was attempted, without checking for their vitality status. When the symptoms did not subside, the patient was operated under local anesthesia and the lesion was sent for histopathological examination which...

Author(s): Rashmi Khanna, Rajeev Khanna, Nagesh Binjoo, H. L. Gupta, Anand Dharams and Pradeep Kumar

  • Article Number: 4154E02967

October 2011

Combination of cultivation and lateral flow assay for easy, highly sensitive and presumptive detection of Bacillus anthracis spores

A combination of cultivation and lateral flow assay detecting protective antigen (PA) for easy and presumptive detection of Bacillus anthracis spores is proposed. This combination is similar to most approaches relying on PCR for detection of spores, as it begins with a 12 h cultivation step. After this culture however, this test is more rapid and far easier to perform than available molecular techniques. With...

Author(s): Valérie Guglielmo-Viret, Nicholas J. Vietri, Françoise Desor and Philippe Thullier

  • Article Number: 32A5187977

August 2011

Tribal distribution of haemoglobinopathies in a Sudanese patient population

Haemoglobin (Hb) abnormalities are inherited disorders in the globin chains when the haem group is in the normal state. They are mostly autosomal recessive abnormalities and common worldwide, particularly within the malarial regions of Africa. This study aimed to identify abnormal Hb stratified tribe by tribe within a cohort of Sudanese patients attending the Khartoum Teaching Hospital between March and July 2005....

Author(s): Abozer Y. Elderdery, Babiker A. Mohamed, Alan J. Cooper, Gavin Knight and  Jeremy Mills

  • Article Number: F3EC225931

August 2011

HLA-DQA1 and -DQB1 genotyping in Individuals with family history of gastritis

The study is aimed examining HLA-DQA1 and HLA-DQB1 genotyping in individuals (patients and controls) with family history of gastritis. This study was carried out in College of Medicine, University of Basrah. HLA-DQA1 and HLA-DQB1 genotyping was done in College of Medicine, University of Manitoba, Winnpeg, Canada during the period from 17 April, 2009 to 15 July, 2010. A total of 100 patients [41 males and 59 females...

Author(s): Nibras S. Al-Ammar, Ihsan Al-Saimary, Saad S. H. Hamadi and Ma Luo

  • Article Number: 9EEFE52951

July 2011

Coinfection of typhoid and malaria

Rampant and unnecessary use of iron supplementation to correct possible anemia in malaria and other infections is dangerous, since excess iron may predispose to salmonellosis. Intracellular bacteria, such as Salmonella typhimurium has an obligate requirement for iron to support intracellular growth and survival. Complements have unique role in salmonella co-infection with malaria because complements like C1q...

Author(s): Prasanna Pradhan

  • Article Number: C608AAD894

July 2011

Streptococcus pneumonia and antimicrobial resistance, Hawassa Referral Hospital, South Ethiopia

Bacterial resistance to antimicrobial agents is an increasing problem in many areas of the tropics. To assess drug resistance pattern of Streptococcus pneumoniae among clinically diagnosed cases of pneumonia, meningitis and otitis media in Hawassa Referral Hospital, Southern Ethiopia. A cross-sectional survey was conducted on 152 cases from sputum, cerebrospinal-fluid, and ear discharge samples. Blood agar and...

Author(s): Deresse Daka, Eskindir Loha and Araya Giday

  • Article Number: C866791910

March 2011

Hypofibronectinaemia in leprosy

The aim of this study is to determine the levels of plasma fibronectin in leprosy patients of Nigerian origin. Seventy leprosy patients, 42 men and 28 women, aged 20 to 70 years, of Mile 4 Hospital Abakalilki in Ebonyi State of Nigeria and seventy age and sex-matched apparently normal subjects were used.  Some (44) of the patients were on multiple drug therapy with dapsone, rifampicin, and clofazimine as the...

Author(s): Ogbu ISI and Ogalagu RO

  • Article Number: 7BC55DB863

March 2011

What is the best approximation of reference normal for NT-proBNP? Clinical levels for enhanced assessment of NT-proBNP (CLEAN)

The natriuretic peptides, B-type natriuretic peptide (BNP) and NT-proBNP that have emerged as tools for diagnosing congestive heart failure (CHF) are affected by age and renal insufficiency (RI). NT-proBNP is used in rejecting CHF and as a marker of risk for patients with acute coronary syndromes. This...

Author(s): Larry H. Bernstein, Michael Y. Zions, Mohammed E. Alam, Salman A. Haq, John F. Heitner, Stuart Zarich, Bette Seamonds and Stanley Berger

  • Article Number: 6C959EC878

January 2011

Comparison of matrix-assisted laser desorption ionization-time of flight mass spectrometry (maldi-tof ms) with conventional culture and biochemical method of bacteria identification to species level

Identification of bacteria to species level is based on culturing in different media which takes 48 to 72 h from the time of isolation. Matrix-assisted desorption ionization-time of flight mass spectrometry (MALDI-TOF MS) is a new technology in bacteria identification. We evaluated MALDI-TOF-MS system with 101 consecutively isolated bacteria colonies under routine laboratory conditions by comparing its identification...

Author(s): Iroha Ifeanyichukwu Romanus, Ayogu Thomas Eze, Oji Anthonia Egwu, Afiukwa Felicitas Ngozi and Nwuzo Agabus Chidiebube

  • Article Number: 9CB0A4C829

January 2011

Prevalence of iron deficiency and iron deficiency anemia among females at university stage

Iron deficiency is the most prevalent nutritional problem in many parts of the world and the most common cause of anemia in Saudi Arabia especially among female. Accordingly, this study was designed to determine the prevalence of iron deficiency and iron deficiency anemia among apparently healthy Saudi young female university students studying at King Abdulaziz University in Jeddah province. Three hundred ten...

Author(s): Fatin Al-Sayes, Mamdooh Gari, Safaa Qusti, Nadiah Bagatian and Adel Abuzenadah

  • Article Number: 3281133843

December 2010

Socio-demographic characteristics of patients presenting pulmonary tuberculosis in a Primary Health Centre, Zaria, Nigeria

Tuberculosis is one of the killer diseases of great antiquity especially in developing countries and so contributes significantly to health instability and economic loss. The directly observed treatment(DOT) course is the recommended standard of care in treatment of tuberculosis worldwide and its key elements lie in making the diagnosis. The study was aimed at examining the socio-demographic characteristics of patients...

Author(s): S. J. Ogboi, S. H. Idris, A. T. Olayinka and Junaid Ilyas

  • Article Number: 16FEAF4798

December 2010

Selenium levels in patients with schizophrenia

The present study was conducted with serum of twenty four patients of schizophrenia and twenty healthy volunteers; and selenium (Se) levels were determined by atomic absorption spectrophotometer. Serum Se levels were significantly increased in schizophrenia patients as compared to healthy controls.  Soil content of Se in Rohtak was found to be lower as compared to Haryana state soil Se levels. These findings...

Author(s): Simmi Kharb, Anjali Sharma, A. K. Vohra, Sanjiv Yadav and Ishwar Singh

  • Article Number: 48D4B8B804

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