International Journal of
Biotechnology and Molecular Biology Research

  • Abbreviation: Int. J. Biotechnol. Mol. Biol. Res.
  • Language: English
  • ISSN: 2141-2154
  • DOI: 10.5897/IJBMBR
  • Start Year: 2010
  • Published Articles: 105

IJBMBR Articles

Gene diversity and identification of putative hybridizing parents for root rot resistance in cassava using simple sequence repeats

October 2012

The incidence of root rot diseases partly contribute to the currently observed low percentage increase in the yield of cassava. We estimated gene diversities and identified putative hybridizing parents for root rot resistance using 18 simple sequence repeats loci in 43 improved genotypes of cassava. Root rot was measured over 2 years as the percentage proportion of rotten roots to the total number of roots harvested at...

Author(s): Oluwasayo Kehinde Moyib,, Jonathan Mkumbira, Oyeronke Adunni Odunola and Alfred Godwin Dixon,

Effect of feeding malted foods on the nutritional status of pregnant women, lactating women and preschool children in Lepakshi Mandal of Ananthapur district, Andhra Pradesh, India

October 2012

Information of preschool children (400), pregnant women (100) and lactating women (100) was collected.  Anthropometric, hemoglobin, clinical and morbidity assessments were carried out before & after supplementation.  Amylase Rich Malted Mixes (ARMMs) 2 types (Ragi/Wheat) were formulated and suitable products namely laddu, roti, kheer and porridge were prepared using formulated malted...

Author(s): Vijaya Khader and K. Uma Maheswari

Enhancing thermostability of the biocatalysts beyond their natural function via protein engineering

June 2012

Majority of the naturally occurring enzymes lacks essential features required during the harsh conditions of the industrial processes, because of their less stability. Protein engineering tool offers excellent opportunity to improve the biochemical properties of these biocatalysts. These techniques further help in understanding the structure and function of the proteins. Most common methods employed in protein...

Author(s): Shelly Goomber, Pushpender K. Sharma, Monika Sharma, Ranvir Singh and Jagdeep Kaur

Extraction, purification and characterization of L-asparaginase from Penicillium sp. by submerged fermentation

June 2012

A fungal strain identified as Penicillium sp. was evaluated for its L–asparaginase enzyme production. The L-asparaginase enzyme was purified to homogeneity from Penicillium sp. that was grown on submerged fermentation. Different purification steps including salt precipitation, followed by separation on sephadex G-100-120 gel filtration and DEAE were applied to obtain pure enzyme preparation....

Author(s): Krishna Raju Patro and Nibha Gupta

Chromium stress on peroxidase, ascorbate peroxidase and acid invertase in pea (Pisum sativum L.) seedling

March 2012

In this investigation, chromium (Cr) toxicity on enzymes like peroxidase, ascorbate peroxidase and acid invertase was studied in pea seedling to evaluate the relative tolerance of the different pea varieties. Effect of Cr (0, 1.0, 2.0, 3.0 mM) on different parts of the seedling that is, cotyledon, plumule and radicle were studied separately to have a comparative study of the enzyme activity in these parts of the plants...

Author(s): Surekha and Joginder Singh Duhan

Histopathological studies of microsporidian infected tissues of Lamerin breed of the silkworm, Bombyx mori L.

March 2012

Ultrastructure of gut and fat bodies of Lamerin breed of the silkworm Bombyx mori L infected with microsporidia did not show hypertropy of cells but structural disorganization was obvious in infected tissues. The different developmental stages (meronts and sporonts) and a few mature spore could be observed in direct contact with cell cytoplasm. Key words: Bombyx...

Author(s): Shabir A. Bhat, B. Nataraju and Ifat Bashir

Studies of wine produced from pineapple (Ananas comosus)

January 2012

Pineapple (Ananas comosus) is the common name for a tropical plant with edible fruit, which is actually a multiple fruit, consisting of coalesced berries. The ratio of 1: 4 (pineapple must: sugar) was used to produce wine using recipes A to D. A contained only natural yeast; B contained natural yeast augmented with granulated sugar; C contained natural yeast augmented with baker’s yeast and granulated sugar...

Author(s): Idise, Okiemute Emmanuel

A survey of avian malaria parasite in Kano State, Northern Nigeria

January 2012

As an attempt to keep abreast of the variety of avian Plasmodium parasite in Kano State, a total of 218 blood films were made from wild (116) and domesticated (102) bird species collected between January and July, 2009 period. The slides were examined for the presence of Plasmodium parasite (parasitaemia value). Birds examined were six Columbidae livia (pigeons), two Cisticola...

Author(s): Karamba K. I, Kawo A. H., Dabo N. T and Mukhtar M. D

Solid lipid nanoparticles as new drug delivery system

December 2011

  The main challenge in cancer chemotherapy is toxic side-effects induced by chemotherapeutic drugs. Thus, alternative methods of drug administration like appropriate drug carrier system is needed to overcome this problem. The main objective of new drug delivery systems is to improve the anti-tumor efficacy of drug and reduce their toxic effects on normal tissues. Recently Solid Lipid Nanoparticles (SLN) as...

Author(s): Abbasalipourkabir, R. Salehzadeh, A. and Rasedee Abdullah

Microbial bioinoculants and their role in plant growth and development

December 2011

The increase in the world's population, coupled with the limitations in the world's supply of natural resources and widespread degeneration of the environment presents a major challenge to agriculturalists. Chemical fertilizer is used to give the plant nutrient requirements within a short period to get faster results. Newly improved varieties of crops need high proportions of fertilizer. But chemical fertilizer...

Author(s): Sujata Dash and Nibha Gupta

Involvement of biotechnology in climate change adaptation and mitigation: Improving agricultural yield and food security

December 2011

  In the context of climate change adaptation and mitigation, biotechnology can respond positively towards reducing vulnerability of natural and human systems to climate change effects. This paper reviews different approaches in which both conventional and modern biotechnology can be employed to address climate change adaptation and mitigation for improved crops adaptability, productivity and food security and...

Author(s): Godliving Y. S. Mtui

Lead toxicity, oxidative damage and health implications. A review

December 2011

  The toxicity of Lead was recognized centuries ago, and it continued to pose serious threat to the health of children as well as adults. This review presents an overview of the current knowledge of toxic effects of Lead induced oxidative damage and also suggests some possible measures which could reduce the toxic effects of the metal. This paper examines the effect s of Lead in blood, soft tissues,...

Author(s): Sadhana Sharma, Veena Sharma, Ritu Paliwal, Pracheta

Studies of wine produced from banana (Musa sapientum)

December 2011

Banana, a wonderfully sweet fruit with firm and creamy flesh that come prepackaged in a yellow jacket, available for harvest throughout the year consists mainly of sugars and fibers which make it a source of immediate and slightly prolonged energy. When consumed, reduces depression, anemia, blood pressure, stroke risk, heartburns, ulcers, stress, constipation and diarrhea. It confers protection for eyesight, healthy...

Author(s): Idise, Okiemute Emmanuel and Odum, Edward Ikenna

Genetic variability among Coleus sp. studied by RAPD banding pattern analysis

December 2011

Genetic improvements of medicinal plants depend on the existence, nature and extent of the genetic variabiles available for manipulation. Genetic analysis with random amplification of polymorphic DNA markers has been extensively used to determine genetic diversity among Coleus sp. and to identify the best quality for human consumption and its medicinal purpose. The objectives of the present study were to assess...

Author(s): Govarthanan M., Guruchandar A., Arunapriya S., Selvankumar T. and Selvam K.

Lung function decline: Screening of alpha-1 antitrypsin gene in a population exposed to coal dust

November 2011

Alpha-1 antitrypsin (AAT) deficiency is an inherited disorder that causes low levels of, or no alpha-1 antitrypsin in the blood. Most commonly, it is associated with chronic obstructive pulmonary disease (COPD). COPD includes chronic bronchitis and emphysema chronic bronchitis - inflammation of the lining of the bronchial tubes emphysema - permanent destruction of the alveoli. Mutations in the PI gene, located on...

Author(s): M. Bhattacharjee, B. G. Unni, S. Das, M. Deka and P. G. Rao

Micropropagation of Allanblackia stuhlmannii: Amenability to tissue culture technique

November 2011

Allanblackia stuhlmannii is an endangered forest tree valued for its edible nut oil. Its limited regenerative potential in the wild hinders the sustainable utilization of its products. To achieve mass production of A. stuhlmannii, its amenability to micropropagation technique was examined. Explants were best surface sterilized at 8% sodium hypochlorite for 10 min and rinsed using sterile distilled water. Of eight basal...

Author(s): Johnstone Neondo, Joseph Machua, Anne Muigai, Aggrey B. Nyende, Moses Munjuga, Ramni Jamnadass and Alice Muchugi

Effects of polysorbate-80 on liver and kidney function in broiler chicken during juvenile growth period

October 2011

An experiment was conducted to examine the effects of polysorbate-80 (PS-80) on liver and kidney function in broiler chicken using 120 one-day-old Cobb 500 chicks. The birds were randomly divided into 6 groups, of 20 birds each (as one replicate) and then allocated to 1 of 6 floor pens (90×180 cm) at the stocking density of 0.08 m2/ bird in a concrete floor,  cross ventilated house. All the birds received the...

Author(s): Khosravinia, H., Manafi M. and Rafiei Alavi, E.

Biofilm forming bacteria isolated from urinary tract infection, relation to catheterization and susceptibility to antibiotics

October 2011

In human medicine, it has been estimated that 65% of nosocomial infections are biofilm associated, loading the health care system enormous costs. These biofilm infections are 10 to 1000 times more resistant to the effects of antimicrobial agents. This study aimed at showing the difference between patients with catheter associated urinary tract infection (CAUTI) and those with non catheter associated (UTI) in terms of...

Author(s): Nermeen Mahmoud Ahmed Abdallah, Shereen Bendary Elsayed, Manal Mohamed Yassin Mostafa and Ghada Metwally El-gohary

Comparative studies on properties of amylases extracted from kilned and unkilned malted sorghum and corn

September 2011

This study investigated the activities of a-amylase, β-amylase and glucoamylase extracted from kilned and unkilned sorghum and corn. Dry grains of sorghum and corn were obtained, steeped and allowed to undergo malting at room temperature for 48 h. Part of the malted starch was kilned by taken into an oven at 50°C for 24 h while the other part was derootted by hand before further processing. a-amylase,...

Author(s): OYEWOLE O. I. and AGBOOLA F. K.

Bacteriological quality and diarrhoeagenic pathogens on River Njoro and Nakuru Municipal water, Kenya

September 2011

Waterborne diarrhoeal pathogens are considered a re-emerging threat and are responsible for considerable morbidity and mortality, especially in developing countries. The objective of this study was to determine bacteriological quality, biochemical oxygen demand and presence of diarrhoeagenic pathogens in water samples collected from River Njoro and Nakuru Municipal water. A total of 432 samples were tested, 216 from...

Author(s): Kiruki Silas, Limo Kiprop Moses, Njagi  Eliud Nyaga Mwaniki and Paul Owuor Okemo  

Molecular characterization of a gene capable of degrading trichloroethylene, an environmental pollutant

September 2011

Trichloroethylene (TCE) is a widely used organic solvent and metal degreasing agent, one of the most frequently detected groundwater contaminants and a potential health hazard. Our novel isolate, Bacillus cereus strain 2479 was capable of degrading TCE efficiently. The gene for TCE degradation was PCR amplified from genomic DNA of B. cereus 2479. The amplified gene was cloned into expression vector pUC I8 in the E. coli...

Author(s): Srijata Mitra and Pranab Roy

An effective method for obtaining high quality messenger ribonucleic acid (mRNA) with minimal ribosomal ribonucleic acid (rRNA) contents

August 2011

Plant transcriptomes are very complex in nature and includes overlapping transcripts, transcribed intergenic regions, and abundant non-coding ribonucleic acids (RNAs). With RNA-Seq approach using next generation sequencing technology, complementary deoxyribonucleic acid (cDNA) library constructed either from Messenger ribonucleic acid (mRNA) or from ribosomal ribonucleic acid (rRNA) minus total RNA can be directly...

Author(s): Vinay Kumar, Kalpesh Katudia, Manoj Kumar Vyas, Navin Srivastava, Kanak Vaidya, Spandan Chaudhary and Surendra Kumar Chikara

Genomic DNA extraction protocols from a Moroccan medicinal and aromatic plant Artemisia herba-alba Asso for RAPD-PCR studies

August 2011

This is the first report on development of protocol for high purity genomic DNA isolation from the Moroccan Artemisia herba-alba schrub leaves and optimization of conditions for RAPD-PCR analysis. Two DNA extraction protocols were specifically developed: QIAgen DNA Kit and protocol developed by Ouenzar et al. (1998). DNA yield and purity were monitored by gel electrophoresis and by determining absorbance at UV...

Author(s): Ourid Ibtissam, Ghanmi Mohamed, EL Ghadraoui Lahsen, Kerdouh Benaissa and Bakkali Yakhlef Salah Eddine

Screening of different insect pests of mulberry and other agricultural crops for microsporidian infection

August 2011

In the present study, different insect pests of mulberry and other agricultural crops were collected from mulberry gardens and agricultural crop fields in and around Mysore, Karnataka, India. The collected insects were screened for microsporidian infection and microsporidian spores were isolated from infected specimens, purified and tentatively designated as NIK- 1Pr, NIK- 1Cc, NIK- 1Cpy, NIK- 1So and NIK- 1Dp. The...

Author(s): Ifat Bashir, S. D. Sharma and Shabir A. Bhat

Authentication of fusion genes in chronic myeloid leukemia

July 2011

Chronic myeloid leukemia is a multifactorial molecular anomaly that confounds the standardization of therapy to date. It is triggered by a broad spectrum of “fused oncoproteins” which are entailed in the disease refractoriness. In Pakistan the molecular diagnosis for leukemia is still in its infancy, as the diagnosis does not efficiently encompass a wide range of the fusion transcripts which are generated as...

Author(s): Aamir Rana, Shahzad Bhatti, Ghulam Muhammad Ali, Shoukat Ali, Nazia Rehman, Sabir Hussain Shah and Ammad Ahmad Farooqi

Sourcing starter cultures for Parkia biglobosa fermentation I: Phylogenic grouping of Bacillus species from commercial ‘iru’ samples

July 2011

Twenty five isolates of Bacillus species were obtained from ten commercial samples of ‘iru’ (fermented African locust bean), after heat-treatment at 80°C for 30 min. All the isolates were Gram-positive, spore-former, catalase-positive, non-motile rods. The phylogenic relationship between the isolates was studied by repetitive PCR fingerprinting using the (GTG)5 primer, referred to as (GTG)5-PCR...

Author(s): Aderibigbe E. Y., Visessanguan W., Sumpavapol P. and Kongtong K.

Genetic polymorphism of growth hormone locus and its association with bodyweight in Grati dairy cows

July 2011

The aim of this research was to study genetic polymorphism in growth hormone (GH) locus and its association with body weight of 43 Grati dairy cows ranging from 2 to 4 years old. Polymorphism of GH locus was ascribed using  a PCR-RFLP method involving restricted enzyme Msp1 on 2% agarose gel. All data were subjeced to statistical analysis based on one way classification model using a statistical software package of...

Author(s): Sucik Maylinda

Antigen specific cellular response in patients with hepatitis C virus infection and its association with HLA alleles

June 2011

Article retracted by the authors

Author(s): Chinmaya Mahapatra and Anuradha S. Tripathy

Decolorization of anthroquinone based dye Vat Red 10 by Pseudomonas desmolyticum NCIM 2112 and Galactomyces geotrichum MTCC 1360

June 2011

Wastewater, from the textile and other dyestuff industries containing synthetic dyes, require prior treatment to prevent groundwater contamination. The microbial decolorization and degradation of these dyes play a pivotal role in this aspect. Pseudomonas desmolyticum NCIM 2112 and Galactomyces geotrichum MTCC 1360 could bring about oxidative degradation resulting in decolorization of this water insoluble Vat Red 10...

Author(s): Archana A. Gurav, Jai S. Ghosh and Girish S. Kulkarni

HLA-DQA1 and –DQB1 genotyping in individuals with family history of gastritis

June 2011

The objective was to study HLA-DQA1 and HLA-DQB1 genotyping in individuals (patients and controls) with family history of gastritis. This study was carried out in College of Medicine, University of Basrah. HLA-DQA1 and HLA-DQB1 genotyping was done in College of Medicine, University of Manitoba, and Winnpeg, Canada during the period from 17th of April 2009 to 15th of July 2010. A total of 100 patients (41 males and 59...

Author(s): Nibras S. Al-Ammar, Ihsan Al-Saimary, Saad Sh. Hamadi and Ma Luo

Drug release and antimicrobial studies on polylactic acid suture

May 2011

The aim of the present study was to develop drug releasing polylactic acid (PLA) suture. PLA suture was taken for the research work. The material was analyzed, its properties, such as tensile strength, elongation, knot strength and diameter. Biopolymers such as chitosan, sodium alginate, calcium alginate, and their blends were coated on the suture material. The polymer coated samples were subjected to Fourier transform...

Author(s): O. L. Shanmugasundaram, R. V. Mahendra Gowda and D. Saravanan

Temperature as a factor in the elaboration of mycotoxins by two fungi in groundnut fodder

May 2011

Production of patulin and terreic acid by Aspergillus terreus and zearalenone by Fusarium oxysporum in groundnut fodder in relation to temperature was investigated. Biodeterioration activity of F. oxysporum and A. terreus was more at incubation temperature of 20 and 30°C respectively. F. oxysporum elaborated maximum amount of zearalenone at 20 to 25°C, while A. terreus could produce maximum terreic acid and...

Author(s): Kiran Saini, S. Kalyani, M. Surekha and S. M. Reddy

Back propagation neural network method for predicting Lac gene structures in Streptococcus pyogenes M Group A Streptococcus strains

April 2011

The rapid growth and availability of whole genome sequences of Streptococcus pyogenes M Group A Streptococcus strains which is a spherical gram-positive bacteria  that causes important human diseases ranging from mild superficial skin infections to life-threatening systemic diseases have initiated the need to analyze these sequences. The motivation of this paper is to adopt content based gene prediction method...

Author(s): Santhosh Rebello, Uma Maheshwari, Safreena and Rashmi Venex DSouza

Proposal for access to the femur in rats

April 2011

Reconstructions, implantation procedures and bone synthesis materials used to treat bone loss caused by tumors or fractures require in vivo testing. In this study, we created an access route to the femur in rats, allowing us to conduct in vivo bone experiments with less cost, more easily obtainable materials and simplified storage and care. Eighteen male Wistar rats, 180 days of age and weighting 350 to 370 g were...

Author(s): Clayton Miguel Costa, Geraldo Bernardes, Sandro Melim Sgrott, Jorge Bins Ely, Luismar Marques Porto and Armando José d’Acampora

In vitro propagation of Rorippa indica L. from nodal and shoot tip explants

March 2011

A simple micropropagation method from nodal and shoot tip explants were reported here for Rorippa indica, an economically important medicinal plant. High frequency of micro shoots were obtained from these two explants on MS medium supplemented with various concentrations of BAP (1.0 to 4.0 mg/l) and Kn (1.0 to 4.0 mg/l). Maximum number of shoots was obtained from nodal explants in the medium containing 3.0 mg/l BAP. The...

Author(s): P. Ananthi, B. D. Ranjitha Kumari and A. Ramachandran

Molecular docking analysis of whey proteins with angiotensin converting enzyme to lessen high blood pressure

March 2011

Angiotensin converting enzyme (ACE) catalyses the conversion of angiotensin I to angiotensin II a potent vasoconstrictor in a substrate concentration dependent manner and degrades bradykinin a potent vasodilator and other vasoactive peptides which leads to increase in blood pressure. Prolonged increase in blood pressure condition increases the risk of heart attacks, heart failure, stroke, or kidney failure....

Author(s): Uma Maheshwari and Shwetha Ashok Shet

Transient receptor potential channels interference has broader implications in safeguarding against genomic instability

February 2011

Prostate cancer is a multistep molecular disorder that arises because of a miscellany of proteins. Calcium channels, hotspots in genome and susceptibility to DNA damage, an illegitimate repair of the genome, all these factors work synchronously at various levels to worsen the clinical management of the disease. Fusion transcripts are recently acclaimed candidates for exacerbation of the disease. Erlotinib has been used...

Author(s): Ammad Ahmad Farooqi, Qaisar mansoor, Aamir Rana, Zeeshan Javed and Shahzad Bhatti

Incidence of mycotoxigenic penicillia in feeds of Andhra Pradesh, India

February 2011

Incidence of different species of Penicillium in poultry feeds (starter, breeder, boiler and layer) and cattle feeds was analyzed. In all twenty three species of Penicillium, Penicillium aethiopicum, Penicillium alli, Penicillium aurantiogriseum, Penicillium brevicampactum, Penicillium camemberti, Penicillium caseifulvum, Pchrysogenum, Penicillium citrinum, Penicillium commune, Penicillium crustosum, Penicillium...

Author(s): V. Koteswara Rao, P. Shilpa, S. Girisham and S. M. Reddy

Construction of genome-length cDNA for foot-and-mouth disease virus serotype Asia 1 IND 63/72 vaccine strain

February 2011

Foot-and-Mouth Disease (FMD) is a highly contagious and economically important viral disease of cloven-hoofed animals. The virus (FMDV) belongs to the genus Apthovirus of the family Picornaviridae. The FMDV genome consists of a positive sense ssRNA of about 8500 nt encoding a single open reading frame (ORF) which later processed into multiple viral proteins. Although FMDV replication resembles those of other picorna...

Author(s): T. Saravanan, C. Ashok Kumar, G. R. Reddy, H. J. Dechamma, G. Nagarajan, P. Ravikumar, G. Srinivas and V. V. S. Suryanarayana

Application of subspecies-specific marker system identified from O. sativa to O. glaberrima accessions and O. sativa × O. glaberrima F1 interspecific progenies

January 2011

Interspecific hybrids (F1's) between Asian rice (Oryza sativa 2n=24 AA) and African rice (Oryza glaberrima 2n=24 AA) are almost completely sterile. This hybrid sterility barrier is mainly caused by an arrest of pollen development at the microspore stage. Intersubspecific F1 hybrid sterility is mainly caused by cryptic chromosomal aberrations and allelic interaction between indica and japonica. To identify O....

Author(s): Isaac Kofi Bimpong, , Joong Hyoun Chin, Joie Ramos and Hee-Jong Koh

Identification of Ralstonia solanacearum using conserved genomic regions

January 2011

The aim of the present study is to develop a scheme for identification of Ralstonia solanacearum with high specificity based on conserved genomic regions. Short Tandem Repeats (STRs) in R. solanacearum genome were searched using Tandem Repeat Finder software. A total of 189 and 74 STRs were found in chromosomal and megaplasmid DNA respectively. Sequence homology of these STRs analyzed using BLAST showed that out of...

Author(s): Alka Grover, Abhinav Grover, S. K. Chakrabarti, Wamik Azmi, Durai Sundar and S. M. P. Khurana

Nutrigenomic analysis of mulberry silkworm (Bombyx mori L.) strains using polymerase chain reaction - simple sequence repeats (PCR-SSR)

December 2010

The DNA marker use in assisting selection are safe method in breeding process and it is an important tool for authentication of new gene cascade in genome. In mulberry silkworm, the major economic and nutrigenomic traits are polygenic in nature. In the present study, we have utilized ten PCR-SSR microsatellite markers to gain better understanding on genotyping of certain nutrigenomic gene loci in nutritionally efficient...

Author(s): Chinnaswamy Ramesha, Savarapu Sugnana Kumari, Chebba Moremnagari Anuradha, Hothur Lakshmi and Chitta Suresh Kumar

Green energy from chemicals and bio-wastes

December 2010

This paper discusses a comprehensive review of biomass energy sources, environment and sustainable development. This includes the biomass energy technologies, energy efficiency systems, energy conservation scenarios, energy savings and other measures necessary to reduce climate change. Energy use reductions can be achieved by minimising the energy demand, by rational energy use, and by recovering heat. The increased...

Author(s): Abdeen Mustafa Omer

Chemical fractionation and heavy metal accumulation in maize (Zea mays) grown on chromated copper arsenate (CCA) contaminated soil amended with cow dung manure

September 2010

Cow dung used as soil amendments and a sequential chemical speciation (six steps) procedure were used to predict the uptake of Cr, Cu and As by maize (Zea mays) plant in chromated copper arsenate (CCA) contaminated soil. A pot experiment containing the contaminated soil samples with different percentage levels of amendments and control (no amendment) was set up. The relative concentrations of the metals in the CCA...

Author(s): S. O. P. Urunmatsoma, E. U. Ikhuoria and F. E. Okieimen

Ethnomedicinal plants and other natural products with anti-HIV active compounds and their putative modes of action

September 2010

The use of ethnomedicines to manage HIV/AIDS has recently gained public interest, although harmonization with official HIV/AIDS policy remains a contentious issue in many countries. Plants and other natural products present a large repertoire from which to isolate novel anti-HIV active compounds. In this literature survey, 55 plant families containing 95 plant species, and other natural products, were found to contain...

Author(s): Kazhila C. Chinsembu and Marius Hedimbi,

Effects of planting dates and compost on mucilage variations in borage (Borago officinalis L.) under different chemical fertilization systems

August 2010

The experimental design was a split factorial on the basis of completely randomized block design with three replications at the expermintal field of the Islamic Azad University, Shahr-e-Qods Branch, Iran in 2009. The planting dates (1 March, 15 March and 1 April) were assigned to the main plots and the combination of compost including 5, 10, 15 and 20 ton ha-1 and the chemical fertilization systems (N1P1K1 = 160, 128,...

Author(s): Ahmad Ebrahimi, Payam Moaveni and Hossein Aliabadi Farahani

Elaboration of mycotoxins by seed-borne fungi of finger millet (Eleusine coracana L.)

August 2010

Mycotoxin producing potential of fungi associated with finger millet was investigated. Many species of Aspergillus elaborated aflatoxins, patulin, terreic acid and sterigmocystin, while species of Fusarium elaborated zearalenone, fusarinone-X, deoxynivalenol, nivalenol, diacetoxyscripenol, neosolanil and HT-2 toxins. Penicillium griseofulvum elaborated cyclopiazonic acid. The toxigenic potential of individual fungus...

Author(s): Shilpa Penugonda, S. Girisham and S. M. Reddy

Antimutagenic activity of aqueous extract of Momordica charantia

July 2010

  Toxicological studies have undergone a significant evolution during the past decade, with inclusion and great emphasis on chronic toxicity, carcinogenicity, teratogenicity and mutagenicity. Present study was taken up to evaluate antimutagenicity of aqueous extract of Momordica charantia (MC) by bone marrow micronucleus assay (MNT) and chromosomal aberration test (CAT) in mice. Cyclophosphamide (100 mg/kg,...

Author(s): Meera Sumanth and G. Nagarjuna Chowdary

Patterns of colonization and immune response elicited from interactions between enteropathogenic bacteria, epithelial cells and probiotic fractions

July 2010

The purpose of this study was to investigate by in vitro studies the antimicrobial activity of eight lactic acid bacterial (LAB) strains belonging to Lactobacillus paracasei spp. paracasei, L. plantarum and L. rhamnosus species against Salmonella enteritidis, Shigella flexneri and EPEC pathogenic strains isolated from pediatric diarrhoea cases, simultaneously with the assessment of the cytotoxicity and immunomodulatory...

Author(s): Mariana Carmen Chifiriuc, Coralia Bleotu, Diana-Roxana Pelinescu, Veronica Lazar, Lia-Mara Ditu, Tatiana Vassu, Ileana Stoica, Olguta Dracea, Ionela Avram and Elena Sasarman

Theileria parva apical membrane antigen-1 (AMA-1) shares conserved sequences with apicomplexan homologs

June 2010

The apical membrane antigen-1 (AMA-1) is a leading malaria vaccine candidate that is expressed in mature stage parasites and is thought to be essential for invasion. In Plasmodium falciparum, AMA-1 is localized initially to the micronemes, apical organelles of the parasite. A similar apicomplexan parasite, Theileria parva infects and transforms lymphocytes of cattle and African buffalo causing the disease called East...

Author(s): Nyerhovwo J. Tonukari

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