Abbreviation: Afr. J. Pharm. Pharmacol.
Start Year: 2007
Page 1 of 100, showing 20 records out of 1990 total, starting on record 1, ending on 20
DOI: 10.5897/AJPP2014.4699[Article Number: 39DE60862384]
The leaves of Ajuga remota benth have been utilized traditionally for the treatment of patients with diabetes mellitus. However, its use has not been scientifically validated. The present study was therefore, aimed to assess the antihyperglycemic and antihyperlipidemic activities of ethanol extract of A. remota leaves in streptozotocin (STZ) induced diabetic rats. Antihyperglycemic and antihyperlipidemic activities of... Read more.
DOI: 10.5897/AJPP2016.4712[Article Number: E3327BE62386]
Rauwolfia vomitoria Aftzel belong to the family of Apocynacea with a common name serpent wood and Igbo name as akanta. It is used traditionally to treat hypertension and rheumatoid arthritis. The present study deals with GC-MS determination and FT-IR analysis of methanolic root extract of the named plant. Exactly thirty phytochemical constituents have been identified by comparing the chromatogram peek values of unknown... Read more.
DOI: 10.5897/AJPP2016.4401[Article Number: B2C5D0C62388]
Pyrazole derivatives (I-VII) were prepared in good yields using aldol condensation followed by cyclization and were characterized by elemental analysis, IR and 1H NMR spectroscopy. In vitro antileishmanial activity test was conducted using Alamar blue reduction method. The test revealed that the synthesized compounds (except compound IIb) exhibit better antileishmanial activity than the standard drug miltefosine and... Read more.
DOI: 10.5897/AJPP2014.4186[Article Number: 2DCCAEC62209]
This study was carried out to determine acute oral toxicity and histopathological effects associated with consumption of Euphorbia heterophylla ethanolic extract using 9 to 10 weeks old Albino mice randomized in six groups. The five groups were orally administered with single graded doses of plant extract at 1500, 2000, 2500, 3500 and 4000 mg/kg body weight while the sixth group was administered 1 ml of physiological... Read more.
DOI: 10.5897/AJPP2016.4678[Article Number: E9EFE7C62211]
In traditional medicine, the leaves of Dacryodes edulis are utilised in the treatment of gastric ulcer and hence, the chloroform and ethanol layers of the chloroform-ethanol extract of the leaves of D. edulis were evaluated for their anti-oxidant vitamin contents and proximate compositions. Based on preliminary investigations, the more promising layer (ethanol layer) was further fractionated and the effects of the... Read more.
DOI: 10.5897/AJPP2015.4312[Article Number: 2A23B6462203]
An important chlorophyll-derived diterpenoid essential oil, phytol (PYT) bio-metabolite, phytanic acid (PA) has a number of pathophysiological contributions. The PA metabolism and its plasma levels associated phenomena are continuously being researched on. This study aims to look at the complete current scenario of PA. The findings suggest that PA has anti-diabetic, cytotoxic, anticancer and anti-teratogenic activities.... Read more.
DOI: 10.5897/AJPP2016.4689[Article Number: CF86F0662160]
We report herein some phytopharmaceutical properties of commonly marketed teas in Nigeria. The organoleptic and physicochemical properties such as color, odor, physical appearance as well as ash value, moisture content, flow properties, pH and solubility were interrogated using standard methods as the measure of their phytopharmaceutical properties. The results show that, all the teas were coarse in nature and the... Read more.
DOI: 10.5897/AJPP2016.4684[Article Number: 4CC37A362172]
Antioxidant capacity, phenolic content, antimicrobial and cytotoxic properties of extracts and fractions from flowers and fruits of G. uruguensis were evaluated. Total phenolic content ranged between 406.8 ± 20.47 and 57.98 ± 1.734 gallic acid equivalent in mg g-1 (mg GAE g-1) samples. Ethyl acetate and butanol fractions from flowers had the greatest rates in phenolic content and antioxidant activity in... Read more.
DOI: 10.5897/AJPP2016.4682[Article Number: E425FAD62107]
The administration of Mesquite pod extract (containing mesquitol, daidzein and genistein) to female and male rats disrupts reproductive variables. However, its effect on fertility is not known. This study evaluated fertility in male and female rats treated with mesquite pod extract, comparing its effects with those of daidzein and estradiol. The following treatments were given for 30 days to groups of female and male... Read more.
DOI: 10.5897/AJPP2016.4686[Article Number: D3E4D5862109]
The açai (Euterpe oleracea Mart) fruit pulp is extensively used in Brazil as food among other uses. The health benefits of açai are largely reported by the Amazon inhabitants. Nonetheless, just a few pharmacological and toxicological studies were made to probe the innocuousness and the safety of the use of this product. The aims of this work were to update knowledge about the chemical composition,... Read more.
DOI: 10.5897/AJPP2016.4670[Article Number: 2D5FFEF62003]
The objective of this study was to identify and evaluate studies that performed the validation of tools applied to health evaluation with a focus on pharmaceutical services. A systematic literature review was conducted to identify validation studies involving pharmaceutical services. The search for articles strategy was held in databases: EMBASE, PubMed/Medline, Scopus, and CINHAL. The descriptors used were:... Read more.
DOI: 10.5897/AJPP2016.4652[Article Number: 44132BD62005]
Progress Test (PrT) is a longitudinal assessment strategy in which tests composed of contents from all the curriculum are periodically applied to all students of a course. Such strategy allows measurement of deep, long-lasting meaningful learning as well as early detection and remediation of underperforming students. It was introduced more than forty years ago, and it has been used in several health schools in the... Read more.
DOI: 10.5897/AJPP2015.4660[Article Number: C38FE0A62007]
A ten year (2006 – 2015) retrospective study was conducted using records from the case files of patients handled at the Usmanu Danfodiyo University Veterinary Teaching Hospital (UDUVTH) in order to ascertain the pattern and problems associated with drug prescriptions in the management of diseases presented to the hospital. The results obtained show that, a total number of 622 patients comprising cattle (4.80%),... Read more.
DOI: 10.5897/AJPP2016.4665[Article Number: 3042DC461981]
Myelo-protective and haematopoietic effects of seed extract fractions (SEF) of Phoenix dactylifera were investigated in Wistar rats. The acute toxicity of the SEF were determined in mice (n=12). Wistar rats (n=45), aged 2 to 3 months and weighing 150 to 220 g were grouped into 9, labeled (A to I). Groups A to D were intraperitoneally-induced for myelo-suppression with 3 mg/kg bodyweight (b.wt) of cyclophosphamide for 7... Read more.
DOI: 10.5897/AJPP2015.4520[Article Number: D88AB1061983]
Oxidative, reductive, lipoxygenase and angiotensin converting enzyme (ACE) activities are the condition where there is an inequity among concentrations can cause a multiple pathological effects. Vast results of medical plants and the remarkable contribution on humans has been observed since centuries. The current study has showed the antioxidant, lipoxygenase, ACE inhibition, urease activity and reducing ability in... Read more.
DOI: 10.5897/AJPP2015.4357[Article Number: 23730ED61820]
Members of the genus Desmodium are widespread in the sub-tropics, tropics and used in traditional medicine, as part of recipes for treating fever, pains, cough and dysentery. In this study, phytochemical screening and comparative anti-inflammatory activities of the methanol extracts, hexane and ethyl acetate fractions of the leaves of Desmodium velutinum and Desmodium scorpiurus were investigated using the... Read more.
DOI: 10.5897/AJPP2016.4675[Article Number: 76C410961824]
The aim of this research was to explore the in vitro antioxidant, antibacterial and anticancer activities of flavonoid rich fraction from the leaves of Enicostemma axillare. The total phenolic and flavonoid contents were assessed by Folin–Ciocalteu and Aluminium chloride method respectively. Antioxidant activities of this plant was confirmed on the source of ABTS (2,2'-azino-bis-3-ethyl... Read more.
DOI: 10.5897/AJPP2016.4636[Article Number: 40840EB61828]
Botulinum toxin type A is one of the most used products in mitigation of wrinkles and expression lines by promoting muscle paralysis. Because of their hydrophilic and high molecular mass, this active has low permeability through the skin. Thus, to exert its action as rejuvenation agent, botulinum toxin needs to be applied through intramuscular injections, causing pain and discomfort to the patient. An alternative to... Read more.
DOI: 10.5897/AJPP2016.4662[Article Number: 4FE928961651]
Research on natural products is facing significant difficulty. The analysis "high-throughput screening" has limited effectiveness in their evaluation. This report on in vitro screening of pharmacological activity of the drugs candidate molecule by evaluating a single target. The presence of many substances in a natural extract makes this process unprecise. The zebrafish (Danio rerio, ZF) is well suited to... Read more.
DOI: 10.5897/AJPP2016.4683[Article Number: DBDB39861653]
The genus, Calliandra is popularly used for renal pain, cystitis, prostate inflammation, fever and toothache. This study aimed at investigating the antinociceptive activity of methanolic crude extract (MCE) of Calliandra umbellifera, regarding chemical (acetic acid, formalin and glutamate tests) of nociception (in vivo) and the methanolic extract and hidrobutanolic phase (HBF) antioxidant activity by the... Read more.
Page 1 of 100, showing 20 records out of 1990 total, starting on record 1, ending on 20