Abbreviation: Afr. J. Pharm. Pharmacol.
Start Year: 2007
Page 1 of 101, showing 20 records out of 2017 total, starting on record 1, ending on 20
DOI: 10.5897/AJPP2017.4770[Article Number: 935D61464395]
A series of several diazenyl schiff base molecules were designed and synthesized through azo coupling of diazotised primary amines with the novel synthesized schiff base ligand (E)-N-((2-chloroquinolin-3-yl)methylene)-4-phenylthiazol-2-amine. All the synthesized molecules have been characterized by different spectral techniques for their structural confirmation. The results of in vitro antioxidant activity of the... Read more.
DOI: 10.5897/AJPP2015.4438[Article Number: AF8B2F164397]
This paper describes the anticholinesterase and antioxidant activities of Eugenia dysenterica DC. (O. Berg. (Myrtaceae) essential oils from leaves (EOED). EOED were obtained by hydrodistillation using a Clevenger-type apparatus and the products were analyzed by gas chromatography-mass spectrometry (GC-MS) and gas chromatography-flame ionization detector (GC-FID). The main constituents of EOED were caryophyllene oxide... Read more.
DOI: 10.5897/AJPP2017.4778[Article Number: 747707A64307]
Atemoya, from family Annonaceae, is an interspecific hybrid between Annona cherimola Mill and Annona squamosa L. It is a tree from a region in diversity of plants, the Caatinga, one of the main Brazilian biomes. In this research, the effects of ethanolic extract of atemoya (Acs-EtOH) were investigated in relief of pain and inflammation in experimental models in rodents. The evaluation of antinociceptive activity was... Read more.
DOI: 10.5897/AJPP2017.4747[Article Number: 68FE7FE64077]
The purpose of this study was to understand and investigate the phytochemical and antimicrobial effects of different fractions of the methanolic extract of Corchorus capsularis leaf. For the extraction of lipophilic compounds with the help of methanol solvent system, cold extraction process was used, where the grinded coarse powder of the leaf was soaked in methanol and kept for four days for proper extraction. After... Read more.
DOI: 10.5897/AJPP2017.4753[Article Number: 07A25F864083]
This study was to evaluate anti-inflammatory and analgesic effects of the aqueous extract of leaves of Chromolaena odorata (Asteraceae) collected in Brazzaville-Congo. Acute inflammation was induced by using the carrageenan and formaldehyde models, and chronic inflammation by the cotton pellet induced granuloma model. Analgesic effect was evaluated by using the acetic acid-induced writhing, the pressure induced by the... Read more.
DOI: 10.5897/AJPP2017.4746[Article Number: 8CA094963894]
This research provided quantitative data for the quality of randomly selected ibuprofen tablets that are sold in both formal and informal market in Harare, Zimbabwe. Fourteen batches of ibuprofen tablets comprising of sixty tablets per batch were randomly selected from retail pharmacies and informal traders over a period of six months. Quality control tests which included physical appearance, uniformity of mass,... Read more.
DOI: 10.5897/AJPP2016.4540[Article Number: AA864FA63896]
The leaves and roots of Clematis hirsuta Perr and Guill is traditionally applied to heal respiratory tract and for the treatment of various animal diseases in different regions of Ethiopia. The objective of this work is to evaluate the antibacterial activities of C. hirsuta. The leaves were collected and air dried in shade at room temperature, made into powder and was soaked in 80% methanol and chloroforms (1 g: 10 ml).... Read more.
DOI: 10.5897/AJPP2017.4762[Article Number: 92CD52463866]
The aerial parts of Capsella bursa-pastoris (L.) Medic are used to treat nephritis, edema and enteritis. Every barber knows that C. bursa-pastoris had a good anti-inflammatory effect. This suggests that the extracted components from C. bursa-pastoris could potentially treat inflammatory disease. For discovering of the anti-inflammatory effects and chemical composition of C. bursa-pastoris, EtOAc extract was extracted... Read more.
DOI: 10.5897/AJPP2017.4736[Article Number: FCB68CB63868]
Geriatric is potentially vulnerable to drug related problems. Inappropriate prescribing to these patient groups causes substantial morbidity and has become an important public health issue. The purpose of this study was to evaluate prescription practice in geriatrics patients attending medical ward of Dessie Referral Hospital (DRH). A cross sectional study design was used to collect data from patient cards aged... Read more.
DOI: 10.5897/AJPP2016.4654[Article Number: 9DE062D63759]
The study was carried out to assess the antioxidant capacity and phytochemical constituents of acetone and water extracts of the vegetables irrigated with fresh and waste water such as Raphanus sativus (Radish), Brassica oleracea capitata (Cabbage), Brassica rapa (Turnip), Coriandrum sativum (Coriander) and Spinacia oleracea (Spinach). A concurrent quantitative investigation of total phenolics, flavonols and flavonoids... Read more.
DOI: 10.5897/AJPP2017.4745[Article Number: E4D3A0F63761]
The aim of this study is to demonstrate the teratogenicity of Riparin III in embryos of Gallus gallus (domestic) at an early stage of development. This study is unprecedented in the literature. Chicken eggs were used to investigate the morphometry. All the groups were incubated at 37.2 ± 0.1°C and 60 ± 5% relative humidity for 24 h. The embryonic disc was identified and the eggs of the control group... Read more.
DOI: 10.5897/AJPP2017.4764[Article Number: 830D3AF63750]
Hibiscus is commonly used traditionally for the treatment of some diseases such as hypertension and as antidiabetic herbal medicine. The objective of the present study is to investigate the effect of the oral administration of aqueous methanolic extract of Hibiscus rosa-sinensis leaves (400 mg/Kg) on streptozotocin (STZ) induced diabetic rats and alteration in liver and kidney functions. The treatment of diabetic rats... Read more.
DOI: 10.5897/AJPP2017.4761[Article Number: 1F6715663576]
Patients undergo nutritional therapy so as to prevent malnutrition or worsening of the condition. When they are unable to receive oral nutrition, the most common form of physiological and nutritional therapy is through enteral nutrition (EN). The drug-nutrient interaction is described as occurring changes in the kinetics or dynamics of the drug or nutrient administered. The purpose of this study is to describe... Read more.
DOI: 10.5897/AJPP2015.4402[Article Number: ECA0C0763748]
Tuberculosis (TB) is the world’s leading curable cause of infectious diseases mortality, with a disproportionate burden of the disease falling on low and middle income countries. In 2013, there was an estimated 9 million incident cases of TB globally and 1.5 million people died from the disease. The estimated number of cases occurred in Asia (56%) and Africa (25%), the incidence rates are highest, driven by high... Read more.
DOI: 10.5897/AJPP2016.4705[Article Number: 5EA640263744]
Dexamethasone is an anti-inflammatory glucocorticoid that may alter glucose and lipid homeostasis depending on the dose and/or duration of administration. Nigella sativa oil (NSO) can be used as potential modulator of intermediary glucose and lipid metabolism. Herein, the authors evaluated the dose-dependent effects of NSO (0.2 and 0.4 ml/kg body weight) supplementation on plasma glucose, insulin and triglyceride... Read more.
DOI: 10.5897/AJPP2017.4744[Article Number: A3956EF63234]
The non-vitamin K antagonist oral anticoagulants have been approved since 2008 for the prevention of systemic embolism and stroke in patients with non-valvular atrial fibrillation with prior stroke, transient ischemic attack, or CHA2DS2-VASc score ≥2. According to the latest guidelines of 2016, if CHA2DS2-VASc score ≥2 for all male patients or if CHA2DS2-VASc score ≥3 for all female patients, oral... Read more.
DOI: 10.5897/AJPP2017.4735[Article Number: 866051E63218]
Annona senegalensis leaves are used in African Traditional Medicine as analgesic and anti-inflammatory drugs. This study aimed to investigate the analgesic and anti-inflammatory activities of total ethereal leaf extract (TEE) of A. senegalensis and its methanolic fraction (MF). Experiments were performed in acetic acid induced contortions in mice and carrageenan rat paw edema. The preventive effect of TEE (100 mg/kg,... Read more.
DOI: 10.5897/AJPP2016.4721[Article Number: 2FD663163210]
Essential oils from six different parts of Blighia unijugata Bak., were obtained using Clevenger-type apparatus; they gave yields between 0.061 and 0.824%. Chemical constituents of the oils were determined using gas chromatography coupled with mass spectrometry (GC-MS). The GC-MS analysis show forty-seven compounds are present in the leaf oil, twenty-one compounds are in stem-bark, twenty-four in stem oil, sixteen in... Read more.
DOI: 10.5897/AJPP2016.4718[Article Number: 810F48263022]
Cynara scolymus L. leaves, popularly known as globe artichoke, have cholagogue and choleretic properties which are attributed to caffeoylquinic acid derivatives. Although, there are already pharmacopoeial methods for quality control of artichoke dry leaf extract, it only shows the assessment of chlorogenic acid determination. This study aimed to adapt and validate a method for simultaneous determination of... Read more.
DOI: 10.5897/AJPP2016.4615[Article Number: 6DE57E063024]
Given the alarming incidence of antibiotic resistance in bacteria of medical importance and multiple side effects associated with the modern day chemotherapeutics, there is a constant need for new and effective therapeutic agents that could be easily extracted from our daily used Nepalese culinary. To study the antibacterial and antioxidant activity of common spices, locally available Clove (Eugenia caryophyllus),... Read more.
Page 1 of 101, showing 20 records out of 2017 total, starting on record 1, ending on 20