African Journal of
Cellular Pathology

OFFICIAL PUBLICATION OF THE SOCIETY FOR CELLULAR PATHOLOGY SCIENTISTS OF NIGERIA
  • Abbreviation: Afr. J. Cell. Path
  • Language: English
  • ISSN: 2449-0776
  • DOI: 10.5897/AJCPath
  • Start Year: 2013

AJCPath Articles

June 2017

Male breast adenomyoepithelioma- A case report and literature review

Adenomyoepithelioma is an uncommon primary breast tumor characterized by a biphasic proliferation of epithelial and myoepithelial cells which was first described by Hampperl in 1970. The largest reported series had been by Tavassoli (1991) who in reported 27 cases. Most of the others have been one or two case reports. Except for two in male patients [Tamura et al., 1993, Berna et al., 1997] all the reported cases have...

Author(s): Wahab TA, Uwakwe H, Gillibrand R, Fafemi O

  • Article Number: D9C9FD355209

June 2017

Haematological changes in layers experimentally infected with salmonella gallinarum

Aim: The present study was conducted to investigate the haematological changes in layers experimentally infected with Salmonella gallinarum. Methods: A total of 20 eighteen-week- old ISA Brown layers were used for the experiment. The birds were randomly divided into two groups, infected and control, of 10 birds each. To establish the infection, each bird in the infected group was orally administered 0.5 ml of the...

Author(s): Chiroma Mohammed Adam, Adamu Sani, Gadzama Joseph John, Esievo King Akpofure Nelson, Abdulsalam Hassan, Sani Nuhu Abdulazeez, Joshua Luka, Muhammad Ya’u

  • Article Number: 34BEC8955205

May 2017

EVALUATION OF THE TOXICITY OF PHYLLANTHUS AMARUS IN WISTAR ALBINO RATS

Aim: The study evaluated the acute and sub acute toxicity of the aqueous leaf extract of Phyllathus amarus Schum. and Thonn using Wistar albino rat. Methods: Sixty-one adult Wistar rats were grouped four groups with ten rats per group for acute study. Rats in group 2, 3 and 4 received 2000mg/kg, 4000mg/kg, and 8000mg/kg of the extract respectively. For sub acute study, rats were divided into three groups with seven...

Author(s): Adomi PO ,Owhe-Ureghe UB , AsagbaSO

  • Article Number: EA3DBD355413

April 2017

A STUDY OF ULCER INDUCED STOMACH OF ALBINO RATS TREATED WITH IDOGU MIXTURE, A POTENT ANTI-ULCER HERBAL DRUG

Aim: The aim of this study was to assess the potency of the anti-ulcer drug, Idogun on the stomach of ulcer induced albino rats. Method: Six groups of locally bred albino rats were used. Each group containing five rats of either sex were orally treated respectively with distilled water (ulcer control group), omeprazole 20mg/kg (reference group) and 100, 200, 400 and 800mg/kg extract of Idogun anti –ulcer...

Author(s): Adediran OA , Avwioro OG and Funsho-Agun AG

  • Article Number: 2677E6255402

March 2017

SEROPREVALENCE AND HAEMATOLOGICAL STUDIES OF SOME WILD AND SEMI-DOMESTICATED BIRDS NATURALLY INFECTED WITH AVIAN POX VIRUS IN ZARIA, NGERIA

Aim: To determine seroprevalence and haematological parameters of some wild and semidomesticated birds naturally infected with avian pox virus (APV). Methods: A total of 160 birds belonging to 12 species were used for the study. Serum samples obtained from these birds were analyzed for antibodies to Avian Pox Virus (APV) using agar gel precipitation test. Natt-Herricks methods and thin blood smear technique were...

Author(s): Andamin AD , AkadeFT , Samuel FU , Enam SJ , Aliyu HB , Abdu PA , Oladele SB

  • Article Number: DC2C7B055394

February 2017

EVALUATION OF THE EFFECTS OF AQUEOUS GARLIC EXTRACT ON LEAD-INDUCED CHANGES ON CEREBELLUM OF WISTAR RATS

Aims: The effects of aqueous garlic extract on lead-induced changes on the cerebellum of Wistar rats was investigated. Methods: Forty five Wistar rats were randomly divided into nine groups. Group 1 served as Control. Groups 2 and 3 received lead at low and high doses. Group 4 received lead and garlic extract at low doses while Group 5 received lead at high dose and garlic extract at low dose. Group 6 received lead...

Author(s): Hamza GA , Ibegbu AO , Buraimoh AA

  • Article Number: 18C297E55385

January 2017

PRELIMINARY HISTOLOGICAL STUDIES ON THE EFFECT OF AQUEOUS FRUIT EXTRACT OF PHOENIX DACTYLIFERA L. (DATE PALM) ON LEAD ACETATE-INDUCED CEREBELLAR DAMAGES IN WISTAR RATS

Aim: This study was to histologically assess the therapeutic effect of aqueous fruit extract of Phoenix dactylifera (AFEPD) on lead acetate-induced cerebellar damage in Wistar rats. Methods: Twenty four rats were grouped into six (I–VI; n=4). Group I (control) received distilled water (1 ml/kg). Group II received lead acetate (LA, 120mg/kg) only. Groups III and IV received LA (120mg/kg) followed by AFEPD...

Author(s): Yusuf AO , Buraimoh AA , Agbon AN , Raji K B , Akpulu PS

  • Article Number: BDE803A55370

June 2015

Evaluation of serum proteins in some immunocompromised patients in Auchi, Edo State, Nigeria

Aim: Immuno compromised state is a condition of alteration in the immune status of an individual, thereby promoting progression of a disease. This work investigated serum proteins in immuno compromised individuals. Methods: 5ml venous blood was collected from 120 volunteers which comprised 20 tuberculosis patients, 40 Human immunodeficiency virus patients, 40 pregnant women and 20 age –sex matched apparently...

Author(s): Okogun GRA , Jemikalajah DJ , Adu ME , Saliu R Okogun GRA , Jemikalajah DJ , Adu ME , Saliu R

  • Article Number: 87299F455478

June 2015

Isolation and serological detection of mycoplasma gallisepticum and mycoplasma synoviae using a combined mg/ms enzyme-linked immunosorbent assay kit in indigenous chickens in Niger State, Nigeria

Aim: The present study was undertaken to determine the seroprevalence of mycoplasma infection and possible isolation from local chickens in Niger State, Nigeria. We have looked into this problem using a combined MG/MS ELISA kit and cultural isolation. Methods: A total of 552 blood samples were randomly collected from exanguinated chickens for serology. Tracheal swabs were collected into screwed cap bijou bottles...

Author(s): Ahmed JS, Lawal SM, Fatihu MY, Moses DG, Barde IJ, Kumbish PR, Oladele SB

  • Article Number: 8CEC3F955483

June 2015

Effect of a cassava based diet (gari) on some renal function parameters in albino rats

Aim: The study was carried out to ascertain the effect of Gari (a cassava based diet) on renal functions in albino rats. Methods: Thirty five Wistar albino rats divided into seven groups were fed Gari mixed with normal rat diet at concentrations of 0, 10, 20, 40, 60, 80, and 100% respectively for 3 weeks and the renal parameters (Creatinine, Urea, Sodium and Potassium) monitored in the animals. Results: There...

Author(s): Adegoke O.A , Bamigbowu E.O , George–Opuda M. I , Awopeju T A , Mbata CA, Braide SA , Ekwusa O. V , Odunfa T

  • Article Number: 16FD54955489

May 2015

Serum biochemical changes in Japanese quail (coturnix coturnix japonica) experimentally infected with salmonella enterica serovar gallinarum

Aim: To determine the serum biochemical changes in Japanese quail (Coturnix coturnix japonica) experimentally infected with Salmonella enterica serovar Gallinarum Methods: A total of 160 (108 males and 52 females) Japanese quails (Coturnix coturnix japonica) were used for the experiment. Four weeks old quails were randomly selected and assigned into four groups (A, B,C and D) of forty quails each. Groups A, B and C...

Author(s): BardeIJ, Bale JOO, Oladele SB, Fatihu MY, Kumbish PR, Rimfa AG, Ahmed JS,Okewole PA

  • Article Number: E2EA72C55435

May 2015

Selected markers of oxidant challenge in essential hypertensive smokers

Aim: The study was set to assess the relationship between antioxidant status, smoking and hypertension, the argument being whether there would be a significant difference in antioxidant status and perhaps, a significant difference in blood pressure. Methods: A total of105 samples were collected. 36 samples were collected from type I hypertensive smokers; 47 from hypertensive non smokers, the remaining 22 were...

Author(s): Odewusi OO, Tope-ajayi AA, Adeshina AA.

  • Article Number: CF50A4155448

May 2015

Effect of ethanolic extract of ocimum gratissimum on sodium nitrite-induced cerebral cortex toxicity in adult wistar rats

Aim: The effect of ethanolic leaf extract of Ocimum gratissimum on sodium nitrite-induced cerebral oxidative stress in adult Wistar rats was evaluated. Methods: Twenty four adult Wistar rats of weight between 150g to 250g were divided into six groups of four rats each. Group I was the Control and received 2ml/kg bwt of distilled water, Group II received 54mg/kg bwt of NaNO2, Group III received 750mg/kg bwt of the...

Author(s): Ibegbu AO, Eze SM, Livinus PP, Adamu SA, Hamman WO, Umana U, Musa SA

  • Article Number: 42F55E455458

May 2015

Prevalence of mycobacterium tuberculosis in Human immunodeficiency virus patients at art centre Agbor, Nigeria

Aim: The prevalence of pulmonary tuberculosis (PTB) in Human immunodeficiency virus (HIV)/Acquired immunodeficiency syndrome (AIDS) patients is a dual epidemic problem of major concern worldwide especially in Africa where there is upsurge of the disease. This study is set to determine the prevalence of PTB among HIV patients. Methods: A total of 489 patients were recruited into the study, 173(35.4%) were males,...

Author(s): Adu ME  , Ezie E  , Isibor CN , Jemikalajah DJ 

  • Article Number: F1C804F55467

April 2015

A study on the stage of presentation of acute kidney injuries to clinics in Western Nigeria

Aim: The research was primarily set to assess the stages at which acute kidney injuries (AKI) are presented for clinical appraisal. Methods: The research was carried out in southwest Nigeria. A total of 151 participants were included, 101 were AKI patients. The remaining 50 were apparently healthy individuals who had no history of AKI, who served as control. Estimation of plasma creatinine was carried out on the...

Author(s): Odewusi OO, Oyedeji SO 

  • Article Number: B8B4B5155399

April 2015

Effect of highly active antiretroviral therapy (haart) on cd4+ cell count and liver enzymes in HIV infection at Lokoja, Nigeria

Aim: To assess the effect of highly active antiretroviral therapy (HAART) on CD4 + cell count and liver enzymes in HIV-infected patients six month  post-therapy based on age and sex distribution. Methods: A cohort of 200 (66 males, 134 females) consenting HAAR  naïve patients, aged between 16 and 65 years with confirmed cases of HIV infection (by Western blot method) at Lokoja, Nigeria having a...

Author(s): Itodo GE , Enitan SS , Samanu VO , Ehiaghe FA , Akele YR , Olanyanju OA

  • Article Number: 57704B755404

March 2015

Effect of highly active antiretroviral therapy (haart) on cd4+ cell count and liver enzymes in HIV infection at Lokoja, Nigeria

Aim: To assess the effect of highly active antiretroviral therapy (HAART) on CD4 + cell count and liver enzymes in HIV-infected patients six months post-therapy based on age and sex distribution. Methods: A cohort of 200 (66 males, 134 females) consenting HAART naïve patients, aged between 16 and 65 years with confirmed cases of HIV infection (by Western blot method) at Lokoja, Nigeria having a baseline CD4 +...

Author(s): Itodo GE , Enitan SS , Samanu VO , Ehiaghe FA , Akele YR , Olanyanju OA ,

  • Article Number: DB2C53355376

February 2015

Sorghum bicolor extract: a suitable counter stain in hibiscus extract nuclear staining of liver and kidney

Aim: To investigate the suitability of alcoholic extract of Sorghum bicolor stalk as a counter stain for Hibiscus extract stained nuclei. Method: Formalin fixed kidney and liver biopsies were processed by the paraffin wax technique, sectioned, stained with Hibiscus extract solution and counterstained with 10% alcoholic extract of Sorghum bicolor stalk. Parallel sections were stained with H&E as control. Results:...

Author(s): Benard SA , Muhammed AO , Fowotade AA , Afolabi OO, Olutunde OA. 

  • Article Number: F39610B55354

February 2015

A review of global guinea worm eradication: emphasis on the Nigerian situation

Aim: The horror and misery of guinea worm with its attendant negative effects on human health and agricultural production is well documented. This study highlights the efforts made so far globally and nationally to eradicate the scourge. Methods: An update on global guinea worm eradication with emphasis on the Nigerian situation was examined. Documented reports by various experts on guinea worm were examined. There...

Author(s): Ezeugwu SMC, Afocha EE, Ajayi MB 

  • Article Number: FFD112E55362

January 2015

Plasma urea and electrolytes profile in different stages of hiv infection in Ekpoma, Nigeria

Aim: Human Immune Deficiency Virus (HIV) is one of most dreaded diseases today. This study aims at the determination of electrolyte profile (Na+ , K+ , Cland HCO3 - ), urea levels and CD4 count of patients diagnosed with HIV infection in Ekpoma, Nigeria. Methods: Sixty patients and 40 apparently healthy individuals as controls were examined from January 2013- September 2014. Electrolytes were assayed using flame...

Author(s): Eshiet EM, Jemikalajah DJ, Okogun GRA

  • Article Number: 870DB9855643

January 2015

Common artifacts and remedies in histopathology (a review)

The essence of preparing a biological specimen for microscopic studies is to get adequate and accurate medical information that is a true representation of the specimen, be it for research or diagnostic purposes. An artifact can be defined as unrelated, self-colored artificial feature found in tissue sections. This has been an age long cause of misinterpretation leading to misdiagnosis to microscopists. The processing...

Author(s): Ekundina VO, Eze G

  • Article Number: E0B172B55645

December 2014

Effect of cigarette smoke on some enzymes of the descending aorta of adult wistar rats (rattus norvegicus)

Aim: The effect of cigarette smoke on the aorta of Wistar rats was investigated for possible enzymatic destruction. Methods: Thirty six Wistar rats 200±10g were randomly grouped into 3 of 12 rats in each group. One group was exposed to cigarette smoke (Benson and Hedges containing 1.1mg nicotine) once daily at 18.00hours. The second group was exposed to smoke from cotton wool of equal weight as of the...

Author(s): Popoola, NA, Enaibe, BU , Adekomi, DA , Raheem, SA , Olajide, OJ , Mustapha, T  

  • Article Number: A11970D55401

December 2014

Prevalence of parasitic agents associated with diarrhoea in children less than 5 years old in Lagos, Nigeria

Aim: Diarrhoea has been a common cause of morbidity and mortality in children less than 5years old. This work was intended to see if the level of hygiene is a reflection of the type of water taken by children. Methods: One hundred and five stool samples were collected from children in two health facilities in Lagos: Ajegunle (52) and Surulere (53) from April to July 2012. The samples from children who had diarrhoea...

Author(s): Ogbonna FN, David AN, Ezeugwu SMC, Onyejepu N, Ajayi MB

  • Article Number: 0E5E70855410

December 2014

The effect of oral administration of the mixture of honey and garcinia kola on the kidney of wistar rats

Aim: Honey and Garcinia kola have long been used separately by the traditional medical practitioners as remedies for cough and other ailments. Recently, a combination of both as a remedy for cough is common. This work was intended to see the effect of this synergy on the kidney. Methods: Twenty five Wistar albino rats weighing 180±10g were grouped into 5 (A, B, C, D, E) of 5 rats each. They were fed twice...

Author(s): Avwioro OG , Demehin AO , Onyije FM , Bini N , Oladele AA , Umukoro S

  • Article Number: C9B93E155424

December 2014

The effect of the mixture of garcinia kola and honey on the liver of wistar rats

Aim: A mixture of honey and Garcinia kola has been used for the treatment of certain dry coughs and diseases. The effect of the recommended dosage of the mixture on the liver was investigated. Methods: Twenty five Wistar albino rats weighing between 170g and 190g were grouped into 5. There were 5 rats each group. The rats were fed twice daily at 8.00am and 6.00pm with a mixture of G. kola and honey 0.16g/kg + 0.5ml,...

Author(s): Avwioro OG, Ogunbayo TJ, Ekhueorhan A, Onyije FM, Adedeji TM

  • Article Number: 120586D55436

December 2014

Phytochemical and trace element analysis of Vernonia Amygdalina (bitter leaf) in different locations in Nigeria

Aim: This study was to evaluate the phytochemical and mineral elements of Vernonia amygdalina leaf grown in Anambra, Imo, Delta and Edo States of Nigeria. Methods: Standard methods were used for the phytochemical screening while the elemental analysis was done by the use of Atomic Absorption Spectrophotometer. Results: The results revealed high concentrations in mg/100g of the bioactive constituents; Flavonoids...

Author(s): Mokogwu ATH, Okorie UP, Digban KA, Abubakar A, Mokogwu EE.

  • Article Number: 2B141D455571

December 2014

Effect of Tamoxifen on the histomorphological and biochemical components of the liver of Guinea Pigs

Aim: Tamoxifen, once praised for its importance in preventing breast cancer recurrence, is now implicated in dangerous side-effects. The authors are not aware of studies on the effect of tamoxifen on the histomorphological and biochemical components of the liver of guinea pig, hence the present one. Methods: Thirty guinea pigs weighing between 650g and 700g were assigned randomly into 6 groups of five and were...

Author(s): Okolie NJC, Okechi OO, Ofor I, Okorochi EC

  • Article Number: CADEEF755573

December 2014

Health point prevalence of helicobacter pylori in central hospital Warri, Nigeria

Aim: More than 50% of the world’s population harbor Helicobacter pylori in their upper gastrointestinal tract. Infection is more prevalent in developing countries, and the incidence is decreasing in the West. This study aims to determine the health prevalence rate H. pylori in Central Hospital Warri. Method: All patients suspected of dyspepsia or/and gastritis from 2012 to 2014 were tested for H. pylori....

Author(s): Jemikalajah DJ, Okogun GRA

  • Article Number: B1DD53C55575

November 2014

Evaluation of serum proteins in pulmonary tuberculosis

Aim: Tuberculosis (TB) remains a major public health problem throughout the world, especially in developing countries with its attendant mortality and morbidity. Proteins in plasma or serum are readily accessible and can be analyzed directly to produce diagnostic information on disease states in patients. Methods: 5ml of venous blood was collected from One hundred (100) volunteers which comprised fifty (50)...

Author(s): Jemikalajah JD, Okogun GRA, Adu ME, Okolie GC

  • Article Number: F78DE2355388

October 2014

The use of arm span to estimate height among the Urhobos in Delta state of Nigeria

Aim: The purpose of this study is to determine the accuracy of arm span as a measure of height among the Urhobos in Delta State of Nigeria. Methods: The nature and scope of this study encompassed 401 adults (199 males and 202 females) aged 22 to 65 years from the Urhobo ethnic group in Delta State of Nigeria. Data was collected with subjects in the anatomical position. Height and arm span were measured with a...

Author(s): Anibor E, Ogbor-Omorie E, Nwagbara A

  • Article Number: A0333F855378

September 2014

The effect of ascorbic acid on mercury-induced changes on the histomorphology of the cerebellum of adult wistar rats

Aim: The present study was aimed at evaluating the effect of ascorbic acid on mercury-induced changes on the cerebellar cortex of adult Wistar rats. Methods: Thirty adult Wistar rats of average weight of 200g were randomly divided into 6 groups of 5 rats each. The animals in Group 1 (control) were administered with distilled water, Groups 2 and 3 were administered with 52mg/kg and 26.25mg/kg body weight of HgCl2...

Author(s): Ibegbu AO, Animoku AA, Ayuba M, Brosu D, Adamu SA, Akpulu P, Hamman WO, Umana UE, Musa SA

  • Article Number: 0AFCBE855359

August 2014

Serum lipid abnormalities in type 2 diabetes mellitus

Aim: Diabetes mellitus is a clinical syndrome characterized by hyperglycemia due to absolute or relative deficiency of insulin. The present study was conducted to determine the lipid profile of diabetes in Delta State. Methods: Serum total cholesterol (TC), triglycerides (TG), high density lipoprotein (HDL), low density lipoprotein (LDL), very low density lipoprotein (VLDL) as well as Body mass index (BMI) were...

Author(s): Adu ME

  • Article Number: 2D5981155466

July 2014

The circumference interorbital index of the Isoko ethnic group in Nigeria

Aim: The aim of the study is to determine the circumference interorbital index amongst the Isoko ethnic group of Nigeria. Methods: This study was based on data collected from 600 Isoko subjects between 12–31 years of age in Delta State of Nigeria. Data was collected using a tape rule to measure the head circumference and a non-stretchable transparent centimeter ruler to measure the inner canthal distance....

Author(s): Anibor E, Ogbor-Omorie E, Ogadima PN

  • Article Number: 486051255455

May 2014

Evaluation of the lethal dose of the methanol extract of rhizophora racemosa leaf using Karber’s method

Aim: To evaluate the median lethal dose (LD50) of the methanol extract of Rhizophora racemosa leaf commonly used for toothache and dysmenorrhoea in the Niger Delta Area of Nigeria. Methods: The modified arithmetic Karber’s method by Aliu and Nwude was used. Various doses of the extract were administered to adult albino rats through intraperitoneal route and the LD50 was calculated. Results: The result...

Author(s): Angalabiri-Owei BE, Isirima JC

  • Article Number: DCA537F55420

May 2014

Histomorpohological assessment of the extract of the stalk of sorghum bicolor as a counterstain

Aim: The objective of this study was to investigate the staining ability of the extract of the stalk of Sorghum bicolor as a counterstain on Haematoxylin. Methods: Tissue blocks of trachea, oesophagus and ileum were retrieved from the Autopsy Block Archive of the Department of Pathology, University of Ilorin Teaching Hospital Ilorin. Eight (8) serial sections labeled A to H were made from each block and stained...

Author(s): Omoowo BT, Bankole JK, Muhammed AO, Benard SA, Afolabi OO

  • Article Number: 971C88555429

May 2014

The effect of Vernonia Amygdalina and Ocimum Gratissimum on Alloxan-induced diabetic rats

Aim: Anti-diabetic evaluation of Vernonia amygdalina and Ocimum gratissimum on alloxan induced diabetic rats was investigated. Methods: Thirty rats were divided into six groups of five per group. The rats were fed with aqueous and ethanolic plant extracts of the plants. Results: On day 2 post induction, fasting blood glucose of all the animals across the groups increased significantly (P<0.05) compared to pre...

Author(s): Adewoga TOS, Sebiomo A, Fagbemi FT

  • Article Number: D22731D55433

May 2014

TESTICULAR ALTERATION IN OVER DOSAGE OF AZATHIOPRINE: A HISTOLOGICAL AND HISTOCHEMICAL STUDY IN WISTAR RATS

Aim: The use of Azathioprine (AZA) in the prevention of organ rejection during transplantation has been documented for different organs of the body. In this study, we investigated the effects of azathioprine on the integrity of the testis of Wistar rats using histological and histochemical techniques. Methods: Eighteen adult male Wistar rats with mean weight 210±2.65 g were randomly assigned into three...

Author(s): Onanuga IO, Ibrahim RB, Amin A, Omotoso GO

  • Article Number: 0B6B1A055437

April 2014

The effect of honey and aloe vera extract on aspirin induced liver damage in rats

Aim: The aim of this study was to investigate the effect of honey and Aloe vera extract on Aspirin-induced liver damage in albino rats. Methods: A total of twenty four adult male albino rats weighing between 100 and 150g were divided into six groups. (A, B, C, D, E and F) of four rats each in a group, Rats in Group A served as control and were given water and feeds only. Rats in Group B were given 100mg/kg of...

Author(s): Adewoga TOS, Sebiomo A

  • Article Number: 60DD12955389

April 2014

Histological and Biochemical effects of aqueous extract of ocimum gratissimum on the liver and kidney of adult wistar rats

Aim: Ocimum gratissimum is used commonly in traditional medicine to treat certain diseases. This study accessed the histological and biochemical effects of aqueous extract of Ocimum gratissimum leaves on the kidney and liver of adult Wistar rats. Methods: Twenty four adult Wistar rats were assigned into four groups (A, B, C and D) of 6 rats each. Group A was used as control, and B, C, and D were the treatment...

Author(s): Ebeye OA, Ekundina OV, Wilkie IE

  • Article Number: ACC12D855393

March 2014

Serum testosterone level in Nigerian marijuana and cigarette smokers

Aim: To evaluate the effects of marijuana and cigarette smoke on serum testosterone level in male marijuana and cigarette smokers. Methods: Testosterone was estimated using enzyme immunoassay on micro plate format in 30 marijuana smokers, 15 cigarette smokers and 25 sex, age matched non-smokers as controls. Body mass index (BMI) of all subjects was also calculated. Results: There was a significant decrease...

Author(s): Adu EM, Popoola OA, Adikema NA

  • Article Number: ACBAFB455351

March 2014

HIV and HBV coinfection in Niger-Delta, Nigeria

Aim: This study was conducted to ascertain the level of coexistence of Hepatitis B virus (HBV) and HIV and to determine their significant association. Both HBV and HIV share the same routes of infection. Methods: The study was conducted on 500 persons consisting 250 subjects who tested positive to HIV and 250 subjects who tested positive to HBV. HIV positive individuals were further tested for HBV. Similarly, HBV...

Author(s): Avwioro OG, Ekene EN, Afadu TE

  • Article Number: F07741B55361

March 2014

Haematologic and biochemical implications of inhalation of fumes of petroleum products

Aims: To investigate the Haematologic and biochemical implications of exposure to fumes of petroleum products in human subjects. Methods: A total of 100 subjects (40 males and 60 females) aged between 18-30 years participated in the study. Each gender was further categorized into two groups of 10 controls and 30 tests in males and 20 controls and 40 tests in females. Test Group 1 subjects were exposed to fumes of...

Author(s): Isirima JC, Angalabiri-Owei BE

  • Article Number: 6AD997155369

February 2014

Effect of stress of examination on serum cortisol level and cd4 cell count in male undergraduates at Igbinedion University, Nigeria

Aim: To assess the effect of stress of examination on serum cortisol level and CD4 cell count in young male students at Igbinedion University. Methods: A cross sectional laboratory based analysis was adopted for this study. A total of 204 male undergraduate volunteers (age 22 + 1.0 years, body mass index 23 + 0.5 kg/m2) were randomly recruited for the study. Total white blood cell (TWBC) was determined using the...

Author(s): Ehiaghe FA, , , Digban K.A., Ehiaghe IJ, .  

  • Article Number: 1643ACC55340

February 2014

Micronutrient levels in workers occupationally exposed to formaldehyde

Aim: The aim of the work was to determine the levels of some micronutrients in the serum of persons occupationally exposed to formalin in Benin City, Nigeria. Methods: The exposed group (n=36) comprised male embalmers (morticians) who have had occupational exposure for a minimum of five years, while apparently healthy age-matched male subjects (n=34) without considerable exposure to formaldehyde served as control...

Author(s): Igharo OG, Osadolor HB, Odigie BE, Ilyas Y, Idemudia OU, Igharo LE, Airhomwanbor K

  • Article Number: E04E7B955342

February 2014

Observations on the quail’s bursa of fabricius under normal and experimental infectious bursal disease conditions

AIM: The study involved the evaluation of the bursa of fabricius in healthy and experimentally infected quails with infectious bursal disease virus (IBDV). METHODS: One hundred and fifty days old quail chicks were obtained and divided into two groups. The Group B birds were inoculated with two drops of IBDV antigen while Group A were inoculated with two drops of phosphate buffered saline per os and kept for 14 weeks....

Author(s): Sonfada ML, Kwari HD, Rabo JS, Wiam IM, Hena SA

  • Article Number: AA027B955345

November 2013

Effect of ascorbic acid on mercuric chloride-induced changes on the cerebral cortex of wistar rats

Aim: The present work was aimed at evaluating the effect of ascorbic acid on mercuric chloride induced changes on the cerebrum of Wistar rats. Methods: Thirty Wistar rats of average weight of 200g were divided into 6 groups of 5 rats each. In addition to normal diet, the animals in Group 1 were given distilled water, Groups 2 and 3 were administered 52mg/kg and 26.25mg/kg of mercuric chloride (HgCl) respectively...

Author(s): Ibegbu AO, Animoku AA, Ayuba M, Brosu D, Adamu SA, Akpulu P, Hamman WO, Umana UE, Musa SA

  • Article Number: 2C433FF55229

November 2013

Prevalence of squamous intraepithelial lesions of the cervix in Jalingo, Nigeria

Aim: Cervical cancer is the second most common cancer among women in Nigeria; fortunately it is preventable through regular screening and management of intraepithelial lesions. This study aims to determine the prevalence of squamous intraepithelial lesions (SIL) of the cervix among women of reproductive age. Methods: All sexually active women between the ages of 16 – 45 years were screened consecutively for...

Author(s): Ahmed SA, Ayuba HU, Maiangwa A, Vakkai VI, Dashe DR, Joel R, Abubakar M, Danga D, Raalueke UA, Kataps HJ

  • Article Number: B4E9CA355227

November 2013

Effect of exercise induced stress on serum cortisol level and cd4 cell count in rats

Aim: To evaluate the effect of exercise induced stress on serum cortisol level and CD4 cells in rats. Methods: A total of 21 male albino rats weighing 100±10g were used for the study. The exercise pre-conditioning was in the form of mere swimming. Serum cortisol was evaluated using Enzyme Linked Immunosorbent Assay. CD4 cell counts were estimated using Partec Cyflow counter, Germany for the quantification...

Author(s): Ehiaghe FA,, Agbonlahor DE, Etikerentse SMO, Osadolor HB

  • Article Number: 81EAF4355225

November 2013

Histopathological pattern of renal tumours seen in Usmanu Danfodiyo University Teaching Hospital Sokoto, Nigeria

Aim: Malignant renal tumour is a relatively rare type of cancer that occurs third in urological tumours after prostate and bladder cancers. Little is known in the literatures about its existence in Sokoto which prompted this research. This study was carried out to determine the prevalence and histopathological pattern of malignant renal tumours in Sokoto, Nigeria. Methods: A total of 11,554 H&E stained sections...

Author(s): Isah RT, Sahabi SM, Adamu SN, Muhammad AT, Mungadi IA

  • Article Number: D7A0DC555223

November 2013

Impact of liver damage on the histoarchitectural profile of the cerebellar cortex in rats

Aim: This study described the histopathological profile of the cerebellar cortex and liver of rats with carbon tetrachloride (CCl4)-induced liver damage. Methods: Male Wistar rats weighing about 250 g were divided into 2 groups (A and B). Group A (control) rats were treated with olive oil (OO) solution only while Group B rats were treated with carbon tetrachloride (CCl4) for 8 weeks. Thereafter, the cerebellum and...

Author(s): Adekomi DA, Oyesomi TO, Ajao MS, Ojo OA, Onikanni SA

  • Article Number: 08AF92A55221

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