Abbreviation: Afr. J. Biochem. Res.
Start Year: 2007
Page 1 of 19, showing 20 records out of 362 total, starting on record 1, ending on 20
DOI: 10.5897/AJBR2017.0955[Article Number: E5FAF0A66906]
The therapeutic effect of an alkaloid-rich fraction of the chloroform-methanol extract of Abrus precatorius seeds on paracetamol-induced hepatotoxicity in rats was investigated in this study. The extract was fractionated in a 17.5 × 2.5 cm Sephadex G15 swollen, packed and eluted with water. The fractions were spotted on F2.54 pre-coated thin layer chromatography (TLC) plates and sprayed with Drangendorff’s... Read more.
DOI: 10.5897/AJBR2017.0955[Article Number: 7C6B58766448]
The antimicrobial activity of spices of human daily diet has been widely demonstrated. Yet, their capacity of promoting antibiotic activity has not been explored adequately. In this work, the chemical composition of essential oils of Piper nigrum and Syzygium aromaticum from Chad were determined and their antimicrobial effect in combination with different antibiotics towards Staphylococcus aureus, Salmonella enteritidis... Read more.
DOI: 10.5897/AJBR2017.0926[Article Number: AE6B57365995]
The Lipoprotein lipase (LPL) is the major triacylglycerol (TAG) hydrolyzing enzyme thus its regulation in different tissues in response to metabolic situations determined lipid consumption or storage. Thyroxine is a well known factor that is able to alter lipoprotein lipase expression. The purpose of this research was to assess the role of 3-iodothyronamine (T1AM) as a thyroid hormone metabolite in regulation of... Read more.
DOI: 10.5897/AJBR2017.0939[Article Number: 85B096E65668]
The aim of our research was to evaluate the cardiovascular risk factors on epileptic patients treated at the Fann University Hospital and to study the influence of haptoglobin (Hp) polymorphism on disease progression. In order to do that, eighty-six (86) patients followed in neurology for at least 2 years were recruited. Each patient was matched to a control according to age and sex. Hp phenotyping was performed by... Read more.
DOI: 10.5897/AJBR2017.0941[Article Number: 7EC9FC565349]
The study involved the production of amylase from Aspergillus niger grown on yam peels in solid state fermentation. The process parameters: temperature, pH (initial) and incubation time were optimized for maximum amylase production using central composite design (CCD) of response surface methodology (RSM). Temperature was the most significant (p<0.05) parameter and the maximum interaction occurred between temperature... Read more.
DOI: 10.5897/AJBR2017.0930[Article Number: 84709A965044]
One of the commonly consumed leafy vegetables in Nigeria is Pterocarpus mildbraedii Harms (Leguminosae) leaf. It has been found that, ethanol and aqueous extracts of the plant leaves exert anti-diabetic effect on rats. This study investigated the effects of ethanol and aqueous leaf extracts of this plant on some hematological parameters and serum cholesterol level in Wistar albino rats. Intraperitoneal administration of... Read more.
DOI: 10.5897/AJBR2016.0914[Article Number: AD4990C64459]
Sansevieria-trifasciata-is commonly known as both in and out door house plant. It is also used in traditional medicine for treatment of influenza, cough and respiratory inflammation. The roots and leaves have secondary metabolites such as saponins that exbihit remedy for cough, snake bite, sprain, bruise, boil, abscess, respiratory inflammation and hair tonic. The plant sample was collected and dried. The... Read more.
DOI: 10.5897/AJBR2017.0934[Article Number: BB7465064065]
This study was aimed to investigate the protective, ameliorative and preventive effects of aqueous Date fruit extract on paracetamol induced nephrotoxicity in wistar rats. A total of 30 male albino wistar rats were used for this study. Rats were randomly divided into five groups containing 6 animals each. Treatments were given daily for fourteen days. The animals in the control group (Group I) did not receive any... Read more.
DOI: 10.5897/AJBR2016.0916[Article Number: 2B1554763391]
The present study was aimed at identifying the functional groups and phyto-constituents present in Xylopia aethiopica (Dunal) A Rich fruit using Fourier Transform Infrared Spectrometry (FTIR) and Gas chromatography-mass spectroscopy (GC-MS), spectroscopy. FTIR method was performed using Perkin Elmer Spectrophotometer and the characteristic peaks were detected. The phytochemical constituents were screened by GC-MS method... Read more.
DOI: 10.5897/AJBR2016.0896[Article Number: D7220DD63198]
Tamarindus indica L is a tropical plant that is used around the world mainly for medicinal purposes. Yet few scientific studies of its biological potential have been undertaken. The aim of this study was to assess the antioxidative potential of T. indica L leaves. The plant material was harvested and then dried in the absence of direct sunlight. The extraction was done by alcoholic decoction, and the fractions were... Read more.
DOI: 10.5897/AJBR2014.0775[Article Number: 0F1657462351]
In this study, pharmacological reactivity of rabbit ileum to crude extract of fruits of Xylopia aethiopica in the presence of other agonist and antagonist agents was evaluated. The contractility of the isolated rabbit ileum was recorded using kymograph. The effects of the crude extract of X. aethiopica on rabbit ileum were independently determined using a dose range of 10-8 to 10-4 mg/ml. However, to determine the... Read more.
DOI: 10.5897/AJBR2015.0862[Article Number: 23BD8B461518]
In this study, the extraction conditions of polysaccharides of Artemisia mongolia (PAM) were optimized and their molecular weight, weight distribution, composition and antioxidant activities of the polysaccharides investigated. The degree of polymerization of fructan-oligosaccharides 2-8 was separated by thin layer chromatography (TLC) with good results. Polysaccharides were extracted from the leaves of A. mongolia and... Read more.
DOI: 10.5897/AJBR2016.0908[Article Number: 840F5F261818]
The present study was carried out during 2012 and 2013 seasons to study the effect of pre-harvest foliar application of chitosan (a natural beta-1-4-linked glucosamine polymer) at two concentrations 250 and 500 ppm on vegetative tree growth, fruit yield and quality as well as leaves chemical composition of Washington navel orange trees grown under two locations. As for growth parameters (shoot length, leaves... Read more.
DOI: 10.5897/AJBR2016.0899[Article Number: 423333761366]
Selected grain extracts were assayed against digestive proteases of Anoplocnemis curvipes, Clavigralla tomentosicollis and Mirperus jaculus with a view to identifying suitable sources of protease inhibitors against the cowpea pests. Laboratory bioassays showed that grains of a local soybean variety Kìshí and a cowpea landrace NG/SA/07/0098 contain potent inhibitors although the former produced a... Read more.
DOI: 10.5897/AJBR2016.0890[Article Number: 3FDBB7760578]
The study evaluated the nephroprotective potentials of methanolic extract (ME) and dichloromethane fraction (DCMF) of root-bark of Garcinia kola on gentamicin-induced nephrotoxicity in rats with a view to utilize the extracts of the root of G. Kola in the amelioration of antibiotic-induced kidney damage. The study involved preparation of the extract, fractionation, phytochemical screening and evaluation of phenolics and... Read more.
DOI: 10.5897/AJBR2016.0884[Article Number: BAF517F58956]
Oil palm calyx is a solid waste in the oil palm industry which is yet to find economic usage. This study aimed to determine the feasibility of recovering phospholipids from the oil palm calyx. Preliminary functional property of calyx phospholipids was determined using emulsion stability. Results indicated that oil palm calyx had 14% total lipids when extracted with methanol and 62.3% of lipids were acetone insoluble... Read more.
DOI: 10.5897/AJBR2015.0866[Article Number: E3A230158333]
Hyperlipidaemia is a usual and life threatening complication of diabetes mellitus. Consequently, a good anti-diabetic agent should reduce the progression of this complication. In view of this, the anti-hyperlipidaemic and anti-atherogenic activities of aqueous extract of Lasianthera africana was studied in streptozotocin induced diabetic rats. Extract treatment was administered at a dose of 1ml of 180 mg/ml of extract... Read more.
DOI: 10.5897/AJBR2015.0854[Article Number: 311921B57709]
This study was conducted to determine the total phenol content (TPC) and free radicals scavenging activity of methanolic and ethanolic extracts of wheat (WH-711) fractions (grain, bran and flour) fermented with Aspergillus oryzae (MTCC 3107). Maximum TPC (1469.35 ± 4.5, 1426.44 ± 5.5 and 1268.91 ± 5.3) was obtained in methanolic extracts as compared to ethanolic extracts (1368.65 ± 3.5,... Read more.
DOI: 10.5897/AJBR2015.0830[Article Number: E8B891356840]
The effect of varying NaCl concentrations on membrane lipids of Escherichia coli and Staphylococcus aureus cultivated at 37°C was studied. Lipid profiles of the membrane extracts were resolved by thin layer chromatography (TLC) using polar and neutral lipids solvent systems, with their fatty acid constituents determined via gas chromatography-mass spectrometry (GC-MS). Polar lipids identified were cardiolipin,... Read more.
DOI: 10.5897/AJBR2015.0839[Article Number: 45AAE4A56842]
This study investigated changes in cholesterol levels and haematological parameters of rats subjected to diets supplemented with kidney bean seeds. The seeds were processed in three parts; the first part was milled raw; the second part was boiled, dried and milled; third part was germinated, dried and milled. The kidney bean seed flour was incorporated into the diet of different groups of rats at 10% inclusion. Thirty... Read more.
Page 1 of 19, showing 20 records out of 362 total, starting on record 1, ending on 20