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Full Length
Research Paper
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Study on the reaction products of hypaconitine in methanol and water using
electrospray ionization mass spectrometry
Yong-gang LIU#, Peng TAN#, Fei LI and
Yan-jiang QIAO*
Beijing University of Chinese Medicine, Beijing, 100102,
China.
*Corresponding author.
E-mail: yjqiao@263.net.
Tel: +86 10 84738620.
#These
authors contributed equally to this work.
Accepted 6 December, 2011. |
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Abstract |
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To identify the products of hypaconitine in
water and methanol, electrospray ionization mass
spectrometry (ESI-MS) method is used to trigger
a full scan product ion experiment for
confirmation. Six hydrolysates were detected,
and their pseudo-molecules are 470, 556, 574,
484, 452 and 588, respectively, indicating
hypaconine, pyrhypaconitine, benzoylhypaconine,
8-methoxyl-hypaconine, dehydration hypaconine
and 8-methoxyl-14-benzoylhypaconine,
respectively. Among them, 8-methoxyl-hypaconine,
8-methoxyl-14-benzoyl-hypaconine and dehydration
hypaconine are identified first in the reaction
products of hypaconitine in methanol.
Key words:
Hypaconitine, electrospray ionization, mass spectrometry.
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