The prevalence of group A
rotavirus infection and some risk factors in pediatric
diarrhea in Zaria, North central Nigeria
and Umoh Jerald2
Unit, Nasarawa State University Keffi, P. M. B. 1022, Keffi,
of Public Health, Faculty of Veterinary Medicine, Ahmadu
Bello University, Zaria, Nigeria.
*Corresponding author. E-mail:
firstname.lastname@example.org. Tel: +2348035884065.
Accepted 8 June, 2010
Group A rotavirus cause infectious, severe and dehydrating
diarrhea which have great impact on childhood morbidity and
mortality worldwide. This study was designed to investigate
the disease burden and risk factors of rotavirus infection
among children 1 – 5 years in Zaria, Nigeria. Stool samples
were collected from 666 diarrheic children and 170 matched
non-diarrheic controls and screened for rotavirus antigen by
ELISA. Their socio-demographic information and clinical
presentations were also noted. There was a 15.6 and 7.6%
prevalence of rotavirus infections among the diarrheic and
non-diarrheic children, respectively, with the peak of
infection occurring between 1 - 6 months of age. The most
common clinical features included dehydration (59.1%), fever
and vomiting (41.3%), vomiting (34.6%) and fever (19.2%).
Age, feeding regimen, and the presence of another person in
the house with diarrhea were found to be risk factors for
rotavirus diarrhea while gender and socioeconomic status
were not. In view of the peak of infection in infants in the
study area, rotavirus vaccine will be best administered in
Rotavirus, prevalence, risk factors, pediatric, diarrhea.