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The use of Psidium guajava Linn. in treating wound,
skin and soft tissue infections
El-Mahmood Muhammad Abubakar
Department
of Microbiology, School of Pure and Applied Sciences,
Federal University of Technology, PMB 2086, Yola, Nigeria.
E-mail:
elmahmud.abubakar33@gmail.com.
Accepted
18 May, 2009. |
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The
antibacterial potential of the crude leaves extracts of
Psidium guajava Linn. against some bacteria associated
with surgical wound, burns, skin and soft tissue infections
were investigated under different conditions. Phytochemical
screening of the crude leaves extracts revealed the presence
of some bioactive compounds that have been associated with
antimicrobial activities. Aqueous extracts was more potent
in inhibiting the growth of pathogenic Proteus mirabilis,
Streptococcus pyogenes, Escherichia coli, Staphylococcus
aureus and Pseudomonas aeruginosa than the
organic extracts. The gram-negative bacteria were less
susceptible to the effects of the crude drugs. The MIC and
MBC values ranged between 6.25 - 50 mg/ml, depending on
extracting solvent and the bacterium in question. Based on
the diameters of zones of growth inhibitions, the crude
extracts were more effective under acidic conditions and
also at low temperatures. The plant can be used for the
formulation of oral antibacterial drugs to manage surgical,
skin and soft tissue infections.
Key
words:
Psidium guajava, antibacterial potential, bioactive
compounds, surgical, soft tissue. |
