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  J. Medicinal Plant Res

 

  Vol. 2 No. 5
 

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 Mann A

 John F


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Journal of Medicinal Plants Research Vol. 2 (5), pp. 094–097, May 2008

ISSN 1996-0875 © 2008 Academic Journals  

   

Full Length Research Paper

 

 

 
 

Phytochemical and antimicrobial activity of Terminalia avicennioides extracts against some bacteria pathogens associated with patients suffering from complicated respiratory tract diseases

 

A. Mann*, Y. Yahaya, A. Banso and F. John

 

Department of Science Laboratory Technology, the Federal Polytechnic, P. M. B 55, Bida, Niger State. Nigeria

 

*Corresponding author.  E-mail:  abdumann@yahoo.com.  Tel. +2348036368173

 

Accepted 29 April 2008

 
     
 

Abstract

 
     
 

Ethanolic extracts of the stem bark, root bark and leaves of Terminalia avicennioides were assayed against Staphylococcus aureus, Escherichia coli and Pseudomonas aeruginosa obtained from patients suffering from complicated respiratory tract infections for their antimicrobial activity. Analysis of variance showed that the ethanolic extracts of the plant material exhibit a significant (P > 0.05) antimicrobial activity against S. aureus. The various zone of inhibitions on Escherichia coli was moderate (P < 0.05) at different concentrations, very low antimicrobial activity was observed against P. aeruginosa. Important bioactive agents like phenols, steroids, glycosides, flavonoids, tannins, ellagic acids were detected in the bark, leaves and root of T. avicennioides.  Anthraquinone was not absent in all the plant parts tested.  The bioactive constituents detected in T. avicennioides may be responsible for the observed antimicrobial activity of the plant and hence, its potential use as antimicrobial agent.

 

Key words: Antimicrobial activity, bacterial pathogens, Phytochemical, respiratory tract diseases, Terminalia avicennioides.

 

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