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Full Length Research
Paper
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Antimicrobial activities
of plumeria acutifolia
Rasool S. N1, Jaheerunnisa S2,
Suresh Kumar Chitta3*and Jayaveera K. N4
1Department
of Biotechnology, Jawaharlal Nehru Technological University,
Hyderabad, India.
2Department
of Microbiology, National Post Graduate College and Research
Centre, Nandyal, A. P., India.
3Department
of Biochemistry, S. K. University, Anantapur, India.
4Department
of Chemistry, JNTU College of Engineering, Anantapur, India.
*Corresponding author. E-mail: chitta34a@gmail.com.
Accepted
20 March 2008 |
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Abstract |
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Ethanolic extract of
Plumeria acutifolia Poir. (Apocynaceae) stembark was tested for
antimicrobial activity against Gram-positive bacteria (Bacillus subtilis,
Enterococcus faecalis, Staphylococcus aureus), Gram-negative bacteria
(Escherichia coli, Klebsiella Pnumoniae, Psuedomonas aeruginosa,
Salmonella typhimurium) and fungi (Aspergillus niger and candida
albicans) by disc diffusion method. Minimal inhibitory concentration
(MIC) and acute toxicity were also assayed. The ethanol extract showed
the strong in vitro antimicrobial activity against E. faecalis, B.
subtilis, S. aureus, P. aeruginosa, S. typhimurium, A. niger and C.
albicans. The extract did not show any toxic symptoms against the tested
mice.
Key words:
Plumeria acutifolia Poir, antibacterial activity, antifungal activity,
disc diffusion, M.I.C, M.B.C/M.F.C, acute toxicity. |
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