activity of selected medicinal plants of Margalla Hills,
Amir Muhammad Khan1*, Rizwana
Aleem Qureshi2, Syed Aneel Gilani3 and
of Plant Sciences, Kohat University of Science and Technology
of Plant Sciences Quaid-i-Azam University, Islamabad, Pakistan.
Museum of Natural History, Islamabad, Pakistan.
*Corresponding author. E-mail:
Accepted 22 June, 2011
The present studies focus on the antimicrobial activities of the
crude methanolic extracts of different plant parts of thirteen
selected medicinal plants namely: Woodfordia
fruiticosa, Adhatoda vasica, Chenopodium
ambrosoides, Viburnum cotinifolium, Euphorbia
hirta, Vitex negundo, Peganum harmala,
Broussonetia papyrifera, Taraxacum officinale,
Urtica dioica, Verbascum thapsus, Caryopteris
grata and Mimosa rubicaulis collected from Margalla
Hills Islamabad, Pakistan against four Gram positive namely:
Staphylococcus aureus, Bacillus subtilis,
Micrococcus luteus and Enterococcus faecalis and five
Gram negative namely: Escherichia coli, Pseudomonas
aeruginosa, Klibsella pneumonia, Vibrio
cholera and Enterobacter coccus bacterial strains.
The fungal strains used were Aspergilus niger,
Aspergilus flavus, Aspergilus fumigates and
Rhyzoctonia solani. Woodfordia fruiticosa,
Chenopodium ambrosoides, Viburnum cotinifolium,
Euphorbia hirta, Vitex negundo and M. rubicaulis
exhibited higher antibacterial activity showing minimum
inhibitory concentration (MIC) values as 1 mg/ml against E.
faecalis and E. coccus. E. hirta was most
affective against E. coli by inhibiting the growth
showing MIC value of 1.0 mg/ml. Maximum antifungal activity
against A. niger was exhibited by C. grata
(87.77%) followed by E. hirta (79.72%) and V.
cotinifolium (72.39%) respectively. A. vasica showed
greater inhibitory properties (89.50%) against A. fumigates.
Maximum inhibitory activity against R. solani was shown
by V. negundo (100%). V. cotinifolium exhibited
maximum activity against A. flavus (88.93%) and A.
Medicinal plants, Margalla Hills, antibacterial, antifungal.