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Journal of Medicinal Plants
Research Vol. 4(23), pp.
2445–2451,
4 December, 2010
DOI: 10.5897/JMPR10.019
ISSN 1996-0875 ©2010 Academic
Journals |
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Full Length Research Paper |
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In vitro
antioxidant activity of acetylated derivatives of polysaccharide
extracted from Ulva pertusa (Cholorophta)
Huimin Qi1,2, Xiaolei Liu3, Juan Ma1,
Quanbin Zhang2* and Zhien Li2
1Weifang
Medical University, No.7166 Baotong Road, Weifang, 261053,
P.R.China.
2Institute
of Oceanology, Chinese Academy of Sciences, Qingdao,
266071, P.R.China.
3Weifang
Preschool and Special Education Normal School, No.1979 Youai
Road, Weifang, 261021, P.R.China.
*Corresponding author. E-mail:
qihuimin78@yahoo.com.cn.
Tel: +86 532 82898708.
Accepted 20 May, 2010 |
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Abstract |
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Polysaccharides obtained from Ulva pertusa (Chlorophyta)
contained a group of sulfated heteropolysaccharide referred to
as ulvan in this paper. In this study, the acetylated ulvans
with different substitution degree were prepared with acetic
anhydride/
p-toluenesulfonyl
chloride in N, N-dimethylacetamide, and
their antioxidant activities were investigated including
scavenging activity on superoxide, hydroxyl radicals and
reducing power. The natural ulvan and its derivatives exhibited
much higher scavenging activity on superoxide radical than
vitamin C. Compared with natural ulvan, the acetylated ulvans
exhibited stronger reducing power. The antioxidant activity of
acetylated ulvans did not increase with increasing substitution
degree. Interestingly, the ulvan (AU4) with highest degree of
substitution showed weakest scavenging effect on hydroxyl
radical.
Key words:
Polysaccharides, Ulva pertusa, antioxidant
activity, acetylated ulvans.
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