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Cassia
species have been of keen interest in
phytochemical and pharmacological research due to their excellent
medicinal values. They are rich sources of polyphenols, anthraquinone
derivatives, flavonoids and polysaccharides. Cassia nigricans
Vahl is an important source of secondary metabolites, notably
anthraquinone derivatives. The leaves of C. nigricans
Vahl have been reported to
contain pharmacologically active substances, including
1,6,8-trihydroxy-3-methyl anthraquinone (emodin), emodic acid,
citreorosein, a flavonoid - luteolin, and hydroxyestranic acid, ethyl
ester. C. nigricans
Vahl is of high therapeutic value
in gastro-intestinal disorders, including ulcers and diarrhoea, and skin
diseases. It possesses antimicrobial, antiulcer, analgesic,
anti-inflammatory, contraceptive, antiplasmodial, insecticidal and
larvicidal activities. The plant has the potential to be used in the
management of agricultural pests. In conclusion, C. nigricans
Vahl
contains biologically active compounds
that may serve as candidates for new drugs in the treatment and
prevention of human and livestock diseases, and pest management.
Key words:
Cassia nigricans
Vahl, ethnomedicine, chemical
constituents, anthraquinones, bioactivities. |
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