The use of medicinal plants as raw materials in the
production of new drugs is ever increasing because of their potentials
in combating the problem of drug resistance in micro-organisms. Demand
for medicinal plants is increasing in both developing and developed
countries. Research on medicinal plants is one of the leading areas of
research globally. However, there is a need to pay closer attention to
the issue of bioactivity-safety evaluation and conservation of medicinal
plants. Although some of the screening tests on medicinal plants are
performed in vitro, the fact still remains that the ultimate aim
of the researcher is to use the medicinal plants to treat diseases in
humans and animals, who has to take the product orally or through other
means into the system. There is also the need to conserve the medicinal
plants to prevent their total extinction from the natural flora. This is
because the expanding trade in medicinal plants has serious implications
on the survival of several plant species, with many under serious threat
to become extinct. The aim of this review is to justify and emphasize
the need for the bioactivity-safety evaluation and conservation of the
medicinal plants.