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Anti fungal activity of
shallot, Allium ascalonicum
Linn. (Liliaceae),
in vitro
A. Z. Mahmoudabadi1* and M. K. G. Nasery2
1Department
of Medical Mycoparasitology, School of Medicine,
and Infectious Diseases and Tropical Research Centre,
Ahvaz
Jundishapur University of Medical Sciences, Ahvaz, Iran.
2Department
of Physiology, School of Medicine, Ahvaz Jundishapur
University of Medical Sciences, Ahvaz, Iran.
*Corresponding author. E-mail:
zarei40@hotmail.com. Tel.: +98 611 3330074. Fax: +98 611
3332036.
Accepted
12 May 2009 |
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The aim of the present study was to investigate anti fungal
activities of the fresh extract of Allium ascalonicum Linn.
(Liliaceae) against clinically important yeast, dermatophytes and some
saprophytic fungi in vitro. The anti fungal effects of fresh
crude juice of shallot were determined against 11 isolates of Candida
albicans, three species of dermatophytes (Microsporum gypseum,
Trichophyton mentagrophytes and Epidermophyton
floccosum) and Syncephalastrum, Aspergillus niger,
Penicillium sp., Paecilomyces sp., Scopulariopsis sp.,
Cladosporium sp., Alternaria sp.,
Drechslera
sp. by agar well
diffusion method.
Minimal
inhibitory concentration (MIC) of the
fresh extract of A. ascalonicum
was
0.25% for most tested fungi; however extract show remarkable activity
against saprophytic fungi followed by Candida species and dermatophytes.
It is concluded that
fresh extract of A.
ascalonicum
has
more anti-saprophytes effect at 0.25% with
a mean diameter of
inhibition zone 21.83 mm.
Key words:
Candida albicans, saprophytic fungi, dermatophyte, Allium
ascalonicum, anti fungal. |
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