Long survival in patients with metastatic leiomyosarcoma of the uterine corpus: A report of 2 cases

S. A. Adewuyi¹*, M. S. Zayyan², P. I. Onwuhafua², M. O. A. Samaila³, A. H. Rafindadi³ and A. O. Oguntayo²

¹Radiotherapy and Oncology Department, Ahmadu Bello University Teaching Hospital, Zaria, Kaduna State, Nigeria.

²Department of Obstetrics and Gynaecology, Ahmadu Bello University Teaching Hospital, Zaria, Kaduna State, Nigeria.

³Department of Pathology, Ahmadu Bello University Teaching Hospital, Zaria, Kaduna State, Nigeria.

*Corresponding author. E-mail: sadewuyi2003@yahoo.com.

Accepted 27 January, 2010

   Abstract

Leiomyosarcoma of the uterus is relatively uncommon in Ahmadu Bello University Teaching Hospital, Zaria - Nigeria and generally has a poor prognosis. A report of palliative treatment for invasive leiomyosarcoma of the uterine corpus with pulmonary metastases in 2 women is presented. Both patients presented with advanced bulky locoregional and metastatic disease. The patients had palliative care using multimodality approach with surgery, chemotherapy and radiotherapy. 2 years after treatment, the patients were alive without evidence of locoregional disease, with one patient having residual pulmonary metastasis. Despite evidence of metastasis, it is possible to have long survival, effective palliative care and improvement in quality of life with multimodality and multidisciplinary collaboration.

Key words: Leiomyosarcoma, uterine corpus, pulmonary metastasis.