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Biotechnol. Mol. Biol. Rev.


Vol. 4 No. 6



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Okeh UM

 

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Biotechnology and Molecular Biology Reviews Vol. 4 (6), pp. 128131, December 2009

ISSN 1538-2273 © 2009 Academic Journals  

 

Standard Review

 

Statistical analysis of the application of Wilcoxon and Mann-Whitney U test in medical research studies

 

U. M. Okeh

 

Department of Industrial Mathematics and Applied Statistics, Ebonyi State University, Abakaliki Nigeria. E-mail: umokeh1@yahoo.com. Tel: +2348034304278.

 

Accepted 11 December, 2009

 

   Abstract

 

Although non-normal data are widespread in biomedical research, parametric tests unnecessarily, predominate in statistical analyses. Five biomedical journals were surveyed and for all studies which contain at least the unpaired t-test or the non-parametric Wilcoxon and Mann-Whitney U test - investigated the relationship between the choice of a statistical test and other variables such as type of journal, sample size, randomization, sponsoring etc. The non-parametric Wilcoxon and Mann-Whitney U were used in 30% of the studies. In a multivariable logistic regression the type of journal, the test object, the scale of measurement and the statistical software were significant. The non-parametric test was more common in case of non-continuous data, in high-impact journals, in studies in humans, and when the statistical software is specified, in particular when SPSS was used.

 

Key words: Wilcoxon and Mann-Whitney U test, univariate analyses, non-parametric test, logistic regression.

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